SECURITIES AND EXCHANGE COMMISSION
                              WASHINGTON, D.C. 20549

                                    FORM 10-K

                  ANNUAL REPORT PURSUANT TO SECTION 13 or 15(d)
                      OF THE SECURITIES EXCHANGE ACT OF 1934

 For the fiscal year ended December 31, 1995      Commission File Number 1-6351

                              ELI LILLY AND COMPANY

       An Indiana Corporation             I.R.S. Employer Number 35-0470950

          Address:   Lilly Corporate Center, Indianapolis, Indiana 46285

             Telephone number, including area code:   (317) 276-2000

           SECURITIES REGISTERED PURSUANT TO SECTION 12(b) OF THE ACT:

                                      Name Of Each Exchange
       Title Of Each Class            On Which Registered
       -------------------            -------------------


       Common Stock                   New York and Pacific Stock Exchanges
  Preferred Stock Purchase Rights     New York and Pacific Stock Exchanges
  8-1/8% Notes Due December 1, 2001   New York Stock Exchange
  8-3/8% Notes Due December 1, 2006   New York Stock Exchange
  6.57% Notes Due January 1, 2016     New York Stock Exchange
  6.77% Notes Due January 1, 2036     New York Stock Exchange


        SECURITIES REGISTERED PURSUANT TO SECTION 12(g) OF THE ACT:   None

 Indicate by  check  mark  whether the  Registrant  (1)  has  filed  all reports
 required to be filed by Section  13 or 15(d) of the  Securities Exchange Act of
 1934 during the preceding  12 months, and (2)  has been subject  to such filing
 requirements for the past 90 days. Yes   X   No
                                         ----    --


 Indicate by check mark if disclosure of  delinquent filers pursuant to Item 405
 of Regulation S-K is  not contained herein, and  will not be  contained, to the
 best of Registrant's knowledge, in the  definitive proxy statement incorporated
 by reference in Part III of this Form 10-K or  any amendment to this Form 10-K.
 [   ]

 Aggregate market value of voting stock of the Registrant held by non-affiliates
 as of February 9, 1996 (Common Stock):  $28,175,758,490

 Number of shares of common stock outstanding as of February 9, 1996:
 552,471,515

 Portions of the following documents have been incorporated by reference into
 this report:

            Document                       Parts Into Which Incorporated
            --------                       -----------------------------


 Registrant's Annual Report to Shareholders        Parts I, II, and IV
  for fiscal year ended December 31, 1995

 Registrant's Proxy Statement dated March 4, 1996  Part III


                                      PART I

  Item 1.   BUSINESS

     Eli Lilly and Company was incorporated in 1901 under the laws of Indiana to
  succeed to the drug manufacturing business founded in Indianapolis, Indiana,
  in 1876 by Colonel Eli Lilly.  The Company*, including its subsidiaries, is
  engaged in the discovery, development, manufacture, and sale of products and
  the provision of services in one industry segment--Life Sciences.  Products
  are manufactured or distributed through owned or leased facilities in the
  United States, Puerto Rico, and 29 other countries, in 19 of which the Company
  owns or has an interest in manufacturing facilities.  Its products are sold in
  approximately 150 countries.  Through its PCS Health Systems subsidiary, the
  Company provides health care management services in the United States.

     Most of the Company's products were discovered or developed through the
  Company's research and development activities, and the success of the
  Company's business depends to a great extent on the continued introduction of
  new products resulting from these research and development activities.
  Research efforts are primarily directed toward the discovery of products to
  diagnose and treat diseases in human beings and animals and to increase the
  efficiency of animal food production.

                               RECENT DEVELOPMENTS

  Divestiture of Medical Device and Diagnostics Businesses

     In 1995 and early 1996, the Company completed the divestiture of its
  Medical Device and Diagnostics ("MDD") businesses.  On September 25, 1995,
  the Company distributed its approximately 80% ownership interest in Guidant
  Corporation (a holding company comprising five of the MDD companies) to
  holders of Lilly common stock through a splitoff ---an exchange offer whereby
  Lilly shareholders were given the opportunity to exchange Lilly shares for
  Guidant shares.  In January 1996, the Company completed the disposition of the
  last remaining MDD company, Hybritech Incorporated, to Beckman Instruments,
  Inc.

  Acquisition of Integrated Medical Systems, Inc.

     In December 1995, the Company acquired Integrated Medical Systems, Inc.,
  which develops and operates physician-focused medical communication networks.
  For further information regarding the business of Integrated Medical Systems,
  see "Health Care Management Services" below.

                    FINANCIAL INFORMATION RELATING TO INDUSTRY
                         SEGMENTS AND CLASSES OF PRODUCTS

     Financial information relating to industry segments and classes of
  products, set forth in the Company's 1995 Annual Report at pages 26-27 under
  "Review of Operations--Segment Information" (pages 13-14 of Exhibit 13 to
  this Form 10-K), is incorporated herein by reference.

- ------
     *The terms "Company" and "Registrant" are used interchangeably herein to
      refer to Eli Lilly and Company or to Eli Lilly and Company and its
      consolidated subsidiaries, as the context requires.

                              1

     Due to several factors, including the introduction of new products by the
  Company and other manufacturers, the relative contribution of any particular
  Company product to consolidated net sales is not necessarily constant from
  year to year, and its contribution to net income is not necessarily the same
  as its contribution to consolidated net sales.

                              PRODUCTS AND SERVICES

  Pharmaceutical Products

    Pharmaceutical products include

       Central-nervous-system agents, including the antidepressant agent
  ProzacR, a selective serotonin reuptake inhibitor, indicated for the treatment
  of depression and, in many countries, for bulimia and obsessive-compulsive
  disorder; the analgesic Darvocet-NR 100, which is indicated for the relief of
  mild-to-moderate pain; and PermaxR, a treatment for Parkinson's disease;

       Anti-infectives, including the oral cephalosporin antibiotics CeclorR
  (cefaclor), KeflexR, and KeftabR, used in the treatment of a wide range of
  bacterial infections; the oral carbacephem antibiotic LorabidR, used to treat
  a variety of infections; the oral macrolide antibiotic DynabacR; the
  injectable cephalosporin antibiotics MandolR, TazidimeR, KefuroxR, and
  KefzolR, used to treat a wide range of infections in the hospital setting;
  NebcinR, an injectable aminoglycoside antibiotic used in hospitals to treat
  various infections caused by staphylococci and Gram-negative bacteria; and
  VancocinR HCl, an injectable antibiotic used primarily to treat staphylococcal
  infections;

       Endocrine products, including HumulinR, human insulin produced through
  recombinant DNA technology; IletinR, animal-source insulin in its various
  pharmaceutical forms; HumatropeR, human growth hormone produced by recombinant
  DNA technology;  and Humalog(TM), a rapid-acting injectable human insulin
  analog of recombinant DNA origin, cleared for marketing in certain overseas
  countries;

       An antiulcer agent, AxidR, an H2 antagonist, indicated for the treatment
  of active duodenal ulcer, for maintenance therapy for duodenal ulcer patients
  after healing of an active duodenal ulcer, and for reflux esophagitis;

       Oncolytic agents, including OncovinR, indicated for treatment of acute
  leukemia and, in combination with other oncolytic agents, for treatment of
  several different types of advanced cancers; VelbanR, used in a variety of
  malignant neoplastic conditions; GemzarR, cleared for marketing in several
  overseas countries for treatment of non-small cell lung cancer and pancreatic
  cancer; and EldisineR, indicated for treatment of acute childhood leukemia
  resistant to other drugs; and

       Additional pharmaceuticals, including cardiovascular therapy products,
  principally ReoPro(TM) and DobutrexR; hematinics; sedatives; and vitamins.
                    

  Animal Health Products

      Animal health products include TylanR, an antibiotic used to control
  certain diseases in cattle, swine, and poultry and to improve feed efficiency

                               2

  and growth; RumensinR, a cattle feed additive that improves feed efficiency
  and growth; CompudoseR, a controlled-release implant that improves feed
  efficiency and growth in cattle; CobanR, MontebanR and MaxibanR, anticoccidial
  agents for use in poultry; ApralanR, an antibiotic used to control enteric
  infections in calves and swine; MicotilR, an antibiotic used to treat bovine
  respiratory disease; and other products for livestock and poultry.

  Health Care Management Services

      PCS provides computer-based prescription drug claims processing, pharmacy
  benefit design, administration and management services, and disease-management
  services to health plan sponsors, including insurance companies, third-party
  administrators, self-insured employers, health maintenance organizations, and
  Blue Cross/Blue Shield organizations that underwrite or administer
  prescription benefit plans.  PCS helps these customers manage prescription
  benefit costs by providing drug utilization reviews, clinically-based
  formularies, generic substitution programs, and disease-management programs.
  RECAPR, PCS's on-line prescription claims management system, is linked with
  over 95% of retail pharmacies in the U.S.  Integrated Medical Systems operates
  physician-based on-line electronic communication networks, called IMS MEDACOMR
  networks, that deliver clinical, administrative, and financial information to
  hospitals, payers/managed-care plans, laboratories, pharmacies, and
  physicians.  Outside the United States the Company is developing pharmacy
  benefits management and disease-management programs in several countries,
  including Canada, the Netherlands, South Africa, and the United Kingdom.

                                    MARKETING

       Most of the Company's major products are marketed worldwide.  Health care
  management services are marketed primarily in the United States, although in
  1995 the Company launched pharmacy benefits management and disease-management
  initiatives in several other markets.

       In the United States, the Company's Pharmaceutical Division distributes
  pharmaceutical products principally through approximately 229 wholesale
  distributing outlets.  Marketing policy is designed to assure immediate
  availability of these products to physicians, pharmacies, hospitals, and
  appropriate health care professionals throughout the country.  Five wholesale
  distributing companies in the United States accounted for approximately 11%,
  9%, 9%, 7%, and 5% respectively, of consolidated net sales in 1995.  No other
  distributor accounted for as much as 5% of consolidated net sales.  The
  Company also makes direct sales of its pharmaceutical products to the United
  States government and to other manufacturers, but those direct sales do not
  constitute a material portion of consolidated net sales.

       The Company's pharmaceutical products are promoted in the United States
  under the Lilly and Dista trade names by one hospital and three retail sales
  forces employing salaried sales representatives.  These sales representatives,
  approximately half of whom are registered pharmacists, call upon physicians,
  wholesalers, hospitals, managed-care organizations, retail pharmacists, and
  other health care professionals.  Their efforts are supported by the Company
  through advertising in medical and drug journals, distribution of literature
  and samples of certain products to physicians, and exhibits for use at medical
  meetings.  In 1994, the Company created a new sales force dedicated to
  diabetes care.

                                3

       In the past few years, large purchasers of pharmaceuticals, such as
  managed-care groups and government and long-term care institutions, have begun
  to account for an increasing portion of total pharmaceutical purchases in the
  United States.  The Company has created special sales groups to service
  government and long-term care institutions, and expanded its managed-care
  sales organization.  In response to competitive pressures, the Company has
  entered into arrangements with a number of these organizations providing for
  discounts or rebates on one or more Company products or other cost-sharing
  arrangements.  The Company has also entered into agreements with generic
  pharmaceutical companies for the promotion, distribution and/or supply of
  generic forms of certain brand name products of both Lilly and other
  companies.

       Outside the United States, pharmaceutical products are promoted primarily
  by salaried sales representatives.  While the products marketed vary from
  country to country, anti-infectives constitute the largest single group in
  total sales.  Distribution patterns vary from country to country.  In recent
  years, the Company has significantly expanded its marketing efforts in a
  number of overseas markets, including emerging markets in Central and Eastern
  Europe, Latin America, Asia and Africa.

       Elanco Animal Health, a division of the Company, employs field
  salespeople throughout the United States to market animal health products.
  Sales are made to wholesale distributors, retailers, feed manufacturers, or
  producers in conformance with varying distribution patterns applicable to the
  various types of products.  The Company also has an extensive sales force
  outside the United States to market its animal health products.

                                  RAW MATERIALS

      Most of the principal materials used by the Company in manufacturing
  operations are chemical, plant, and animal products that are available from
  more than one source.  Certain raw materials are available or are purchased
  principally from only one source.  Unavailability of certain materials from
  present sources could cause an interruption in production pending
  establishment of new sources or, in some cases, implementation of alternative
  processes.

      Although the major portion of the Company's sales abroad are of products
  manufactured wholly or in part abroad, a principal source of active
  ingredients for these manufactured products continues to be the Company's
  facilities in the United States.

                               PATENTS AND LICENSES

       The Company owns, has applications pending for, or is licensed under, a
  substantial number of patents, both in the United States and in other
  countries, relating to products, product uses, and manufacturing processes.
  There can be no assurance that patents will result from the Company's pending
  applications.  Moreover, patents relating to particular products, uses, or
  processes do not preclude other manufacturers from employing alternative
  processes or from successfully marketing substitute products to compete with
  the patented products or uses.  Patent protection of certain products,
  processes, and uses--particularly that relating to Prozac, Axid, and Lorabid-
  is considered to be important to the operations of the Company.  The United
  States compound patent covering Prozac expires in 2001, the Axid compound
  patent expires in 2002, and the Lorabid compound patent expires in 2006.

                               4

       The Company also grants licenses under patents and know-how developed by
  the Company and manufactures and sells products and uses technology and know-
  how under licenses from others.  Royalties received by the Company in relation
  to licensed pharmaceuticals amounted to approximately $4 million in 1995, and
  royalties paid by it in relation to pharmaceuticals amounted to approximately
  $109 million in 1995.

                                   COMPETITION

      The Company's pharmaceutical products compete with products manufactured
  by numerous other companies in highly competitive markets in the United States
  and throughout the world.  The Company's animal health products compete on a
  worldwide basis with products of pharmaceutical, chemical, and other companies
  that operate animal health divisions or subsidiaries.  PCS faces strong
  competition from other pharmacy benefit management companies and claims
  processors in the United States.  For certain accounts, PCS competes with some
  retail pharmacy chains, mail order programs and organized groups of
  independent pharmacists.

      Important competitive factors include price and demonstrated cost-
  effectiveness, product characteristics and dependability, service, and
  research and development of new products and processes.  The introduction of
  new products and processes by competitors with therapeutic or cost advantages
  can result in progressive price reductions or decreased volume of sales of
  competing products, or both.  New products introduced with patent protection
  usually must compete with other products already on the market at the time of
  introduction or products developed by competitors after introduction.
  Manufacturers of generic products typically invest far less in research and
  development than research-based pharmaceutical companies and accordingly are
  able to price their products significantly lower than branded products.
  Therefore, upon patent expiration, branded products often face intense price
  competition from generic forms of the product.  In many countries patent
  protection is weak or nonexistent.  The Company believes its long-term
  competitive position is dependent upon the success of its research and
  development endeavors in discovering and developing innovative, cost-effective
  products, together with increased productivity resulting from improved
  manufacturing methods, marketing efforts, and the provision of value-added
  services to its customers.  There can be no assurance that the Company's
  research and development efforts will result in commercially successful
  products or that products manufactured or processes used by the Company will
  not become outmoded from time to time as a result of products or processes
  developed by its competitors.

                             GOVERNMENTAL REGULATION

       The Company's operations have for many years been subject to extensive
  regulation by the federal government, to some extent by state governments, and
  in varying degrees by foreign governments.  The Federal Food, Drug, and
  Cosmetic Act, other federal statutes and regulations, various state statutes
  and regulations, and laws and regulations of foreign governments govern
  testing, approval, production, labeling, distribution, post-market
  surveillance, advertising, promotion, and in some instances, pricing, of most
  of the Company's products.  The lengthy process of laboratory testing,
  clinical testing, data analysis and regulatory review necessary for required
  governmental approvals is extremely costly and can significantly delay product
  introductions in a given market.  In addition, the Company's operations are
  subject to complex federal, state, local, and foreign environmental and
  occupational safety laws and regulations.  It is anticipated that compliance
  with regulations affecting the manufacture and sale of current products and

                           5

  the introduction of new products will continue to require substantial
  scientific and technical effort, time, and expense and significant capital
  investment.

       In the United States, health care reform was not debated extensively at
  the federal level in 1995 and the Company does not expect major federal health
  care reform legislation to be adopted in the near future.  However, various
  health care reform and pharmaceutical reimbursement measures are being
  considered in a number of states.  Outside the United States, changes in
  health care delivery and pharmaceutical reimbursement are occurring to varying
  degrees which in some cases may adversely affect pharmaceutical industry
  revenues.  The Company is unable to predict the extent to which its business
  may be affected by these or other future legislative and regulatory
  developments.

                             RESEARCH AND DEVELOPMENT

       The Company's research and development activities are responsible for the
  discovery or development of most of the products offered by the Company today.
  Its commitment to research and development dates back more than 100 years.
  The Company invests heavily in research and development, which management
  believes is critical to long-term competitiveness in the pharmaceutical
  industry.  The growth in research and development expenditures and personnel
  over the past several years demonstrates both the continued vitality of the
  Company's commitment and the increasing costs and complexity of bringing new
  products to the market.  At the end of 1995, approximately 4,800 people,
  including a substantial number who are physicians or scientists holding
  graduate or postgraduate degrees or highly skilled technical personnel, were
  engaged in pharmaceutical and animal health research and development
  activities.  The Company expended  $755.0 million on these research and
  development activities in 1993, $838.7 million in 1994, and $1,042.3 million
  in 1995.

       The Company's research is concerned primarily with the effects of
  synthetic chemicals and natural products on biological systems.  The results
  of that research are applied to the development of products for use by or on
  humans and animals, and for other uses.  Major effort is devoted to
  pharmaceutical products.  The Company concentrates its pharmaceutical research
  and development efforts in five therapeutic categories:  central nervous
  system and related diseases; endocrine diseases, including diabetes and
  osteoporosis; infectious diseases; cancer; and cardiovascular diseases.  The
  Company is engaged in biotechnology research programs involving recombinant
  DNA, protein research, and genomics (the development of therapeutics through
  identification of disease-causing genes and their cellular function).

       In addition to the research activities carried on in the Company's own
  laboratories, the Company sponsors and underwrites the cost of research and
  development by independent organizations, including educational institutions
  and research-based human health care companies, and contracts with others for
  the performance of research in their facilities.  It utilizes the services of
  physicians, hospitals, medical schools, and other research organizations in
  the United States and numerous other countries to establish through clinical
  evidence the safety and effectiveness of new products.  The Company's
  business-development groups actively seek out opportunities to invest in
  external research and technologies that hold the promise to complement and
  strengthen the Company's own research efforts in the five chosen therapeutic
  categories.  Such investments can take many forms, including licensing
  arrangements, co-development and co-marketing agreements, and outright
  acquisitions.

                             6

       Extensive work is also conducted in the animal sciences, including animal
  nutrition and physiology and veterinary medicine.  Certain of the Company's
  research and development activities relating to pharmaceutical products may be
  applicable to animal health products.  An example is the search for agents
  that will cure infectious disease.

                                QUALITY ASSURANCE

       The Company's success depends in great measure upon customer confidence
  in the quality of the Company's products and in the integrity of the data that
  support their safety and effectiveness.  The quality of the Company's products
  arises from the total commitment to quality in all parts of the Company,
  including research and development, purchasing, facilities planning,
  manufacturing, and distribution.  Quality-assurance procedures have been
  developed relating to the quality and integrity of the Company's scientific
  information and production processes.

       Control of production processes involves rigid specifications for
  ingredients, equipment, facilities, manufacturing methods, packaging
  materials, and labeling.  Control tests are made at various stages of
  production processes and on the final product to assure that the product meets
  all regulatory requirements and the Company's standards.  These tests may
  involve chemical and physical chemical analyses, microbiological testing,
  testing in animals, or a combination of these tests.  Additional assurance of
  quality is provided by a corporate quality-assurance group that monitors
  existing pharmaceutical and animal health manufacturing procedures and systems
  in the parent company, subsidiaries, and affiliates.

                        EXECUTIVE OFFICERS OF THE COMPANY

       The following table sets forth certain information regarding the
  executive officers of the Company.  All but three of the executive officers
  have been employed by the Company in executive or managerial positions during
  the last five years.  Randall L. Tobias became Chairman of the Board and Chief
  Executive Officer in June 1993.  He had served as Vice Chairman of the Board
  of AT&T from 1986 until he assumed his present position.  He has been a member
  of the Board of Directors of the Company since 1986.  Charles E. Golden joined
  the Company as Executive Vice President and Chief Financial Officer and was
  elected to the Board of Directors on March 4, 1996.  He previously had held a
  number of executive positions with General Motors Corporation ("GM")
  including Vice President of GM and Chairman and Managing Director of Vauxhall
  Motors Limited, a GM subsidiary in the United Kingdom, from 1993 to 1996, Vice
  President and Treasurer from 1992 to 1993, and Treasurer from 1989 to 1992.
  Thomas Trainer joined the Company in January 1995.  Since 1991 he had served
  as Vice President and Chief Information Officer of Reebok International Ltd.
  Prior to joining Reebok, he was Senior Vice President of Operations of A.C.
  Nielson Co.

       Except as indicated in the following table, the term of office for each
  executive officer indicated herein expires on the date of the annual meeting
  of the Board of Directors, to be held on April 15, 1996, or on the date his or
  her successor is chosen and qualified.  No director or executive officer of
  the Company has a "Family relationship" with any other director or executive
  officer of the Company, as that term is defined for purposes of this
  disclosure requirement.  There is no understanding between any executive
  officer of the Company and any other person pursuant to which the executive
  officer was selected.

                               7

       NAME                AGE                 OFFICES
  ----------------------------------------------------------------------


  Randall L. Tobias        54   Chairman of the Board and Chief Executive
                                Officer (since June 1993) and a Director

  Sidney Taurel            47   President and Chief Operating Officer (since
                                February 1996) and a Director

  Charles E. Golden        49   Executive Vice President and Chief Financial
                                Officer (since March 1996) and a Director

  August M. Watanabe, M.D. 54   Executive Vice President, Science and
                                Technology (since February 1996) and
                                a Director

  Mitchell E. Daniels, Jr. 46   President, North American Pharmaceutical
                                Operations (since April 1993)1

  Michael L. Eagle         48   Vice President, Manufacturing (since January
                                1994)

  Brendan P. Fox           52   President, Elanco Animal Health Business Unit
                                (since January 1991)1

  Rebecca O. Goss          48   Vice President and General Counsel (since March
                                1995)

  Michael E. Hanson        48   President, Internal Medicine Business Unit
                                (since August 1994)1

  James A. Harper          48   President, Endocrine Business Unit (since August
                                1994)1

  Pedro P. Granadillo      48   Vice President, Human Resources (since
                                April 1993)

  Gerhard N. Mayr          49   President, European Pharmaceutical Operations
                                (European, Middle East and African Operations)
                                (since January 1993)1

  Robert N. Postlethwait   47   President, Central Nervous System Business Unit
                                (since August 1994)1

  William R. Ringo         50   President, Infectious Diseases and Generics
                                Business Unit (since September 1995)1

  Gino Santini             39   Vice President, Corporate Strategy and Business
                                Development (since September 1995)

  Thomas Trainer           49   Vice President, Information Technology, and
                                Chief Information Officer (since January 1995)1

- ------------
1 Serves in office until successor is appointed.

                             8

                                    EMPLOYEES

       At the end of 1995, the Company had approximately 26,800 employees,
  including approximately 11,500 employees outside the United States.  A
  substantial number of the Company's employees have long records of continuous
  service.

        FINANCIAL INFORMATION RELATING TO FOREIGN AND DOMESTIC OPERATIONS

       Financial information relating to foreign and domestic operations, set
  forth in the Company's 1995 Annual Report at pages 26-27 under "Review of
  Operations--Segment Information" (pages 13-14 of Exhibit 13), is incorporated
  herein by reference.

       Eli Lilly International Corporation, a subsidiary, coordinates the
  Company's manufacture and sale of products outside the United States.

       Local restrictions on the transfer of funds from branches and
  subsidiaries located abroad (including the availability of dollar exchange)
  have not to date been a significant deterrent in the Company's overall
  operations abroad.  The Company cannot predict what effect these restrictions
  or the other risks inherent in foreign operations, including possible
  nationalization, might have on its future operations or what other
  restrictions may be imposed in the future.

  Item 2.   PROPERTIES

       The Company's principal domestic and international executive offices are
  located in Indianapolis.  At December 31, 1995, the Company owned 14
  production plants and facilities in the United States and Puerto Rico.  These
  plants and facilities contain an aggregate of approximately 12.2 million
  square feet of floor area.  Most of the plants and facilities involve
  production of both pharmaceutical and animal health products.  The Company
  also leases sales offices in a number of cities located in the United States
  and abroad.  PCS owns or leases administrative facilities in Scottsdale,
  Arizona, containing an aggregate of approximately 475,000 square feet and
  leases administrative space in other cities in the United States.  Integrated
  Medical Systems leases approximately 84,000 square feet of administrative
  space in a number of locations.

       The Company has 23 production plants and facilities in 19 countries
  outside the United States, containing an aggregate of approximately 4.2
  million square feet of floor space.  Leased production and warehouse
  facilities are utilized in Puerto Rico and 17 countries outside the United
  States.

       The Company's research and development facilities in the United States
  consist of approximately 2.8 million square feet and are located primarily in
  Indianapolis and Greenfield, Indiana.  Its major research and development
  facilities abroad are located in Belgium and the United Kingdom and contain
  approximately 435,000 square feet.  The Company also owns two tracts of land,
  containing an aggregate of approximately 1,700 acres, a portion of which is
  used for field studies of products.

       The Company believes that none of its properties is subject to any
  encumbrance, easement, or other restriction that would detract materially from
  its value or impair its use in the operation of the business of the Company.
  The buildings owned by the Company are of varying ages and in good condition.

                                9

  Item 3.   LEGAL PROCEEDINGS

       Product Liability Litigation.  The Company is currently a defendant in a
  variety of product litigation matters involving primarily diethylstilbestrol
  ("DES") and Prozac.  In approximately 265 actions, including several with
  multiple claimants, plaintiffs seek to recover damages on behalf of children
  or grandchildren of women who ingested DES during pregnancy.  In March 1996 a
  suit was filed in the federal district court for the Eastern District of New
  York against the Company and several other manufacturers purporting to be a
  nationwide class action on behalf of women who were exposed to DES in utero.
  The suit does not seek compensation for personal injuries but instead seeks
  establishment of a fund for various expenses allegedly incurred as a result of
  DES exposure.  In another approximately 70 actions, plaintiffs seek to recover
  damages as a result of the ingestion of Prozac.

       Pricing Litigation.   The Company has been named, together with numerous
  other U.S. prescription pharmaceutical manufacturers and in some cases
  wholesalers or distributors, as a defendant in a large number of related
  actions brought by retail pharmacies and consumers of prescription
  pharmaceuticals in the United States alleging violations of federal or state
  antitrust laws, or both, based on the practice of providing discounts or
  rebates to managed-care organizations and certain other purchasers.  The
  federal cases have been consolidated or coordinated in the Northern District
  of Illinois as In re Brand Name Prescription Drugs Antitrust Litigation (MDL
  No. 997).

       The federal suits include a certified class action on behalf of a
  majority of retail pharmacies in the United States (the "Federal Class
  Action").  The class plaintiffs allege an industrywide agreement in violation
  of the Sherman Act to deny favorable pricing on sales of brand-name
  prescription pharmaceuticals to certain retail pharmacies in the United
  States.  The Federal Class Action is scheduled to begin trial May 7, 1996.
  The Company and eleven other manufacturers have agreed to settle the Federal
  Class Action.  The settlement amount, which is not material, was accrued by
  the Company in the fourth quarter of 1995.  The settlement is subject to
  approval of the District Court.  A hearing on the proposed settlement is
  scheduled for March 27, 1996.  The other federal suits, brought as individual
  claims by several thousand pharmacies, allege price discrimination in
  violation of the Robinson-Patman Act as well as Sherman Act claims.  The suits
  seek treble damages and injunctive relief against allegedly discriminatory
  pricing practices.  Defense motions for summary judgment on the Sherman Act
  claims in these suits are pending.  With respect to the Robinson-Patman Act
  claims, the District Court has designated certain plaintiffs and defendants
  named in the individual suits (not including the Company) to participate in an
  initial trial or trials of the claims.  No trial dates have been set.
  Robinson-Patman claims asserted in the suits against nondesignated defendants,
  including the Company, are stayed.

       In addition, there are a number of related state court cases.  The state
  court suits typically seek money damages and injunctive relief against
  allegedly discriminatory pricing practices.  Cases have been brought in
  Alabama, California, Minnesota, and Wisconsin by large numbers of retail
  pharmacies alleging violations of various state antitrust and pricing laws,
  purporting to be class actions on behalf of retail pharmacies in those states.
  The court in California has certified a class of retail pharmacies.  Cases
  have also been brought in state courts in Alabama, Arizona, California,
  Colorado, District of Columbia, Maine, Michigan, Minnesota, New York,
  Washington and Wisconsin that purport to be class actions on behalf of
  consumers of prescription pharmaceuticals, alleging violations of state
  antitrust and pricing laws.  The courts in Alabama and California have

                                10

  certified classes of consumer plaintiffs.  The Colorado and Washington cases
  have been dismissed and appeals are pending.  The Maine case has been removed
  to federal court but a motion to remand to the state court is pending.

       Other Litigation.  In June 1995, a California retail pharmacy filed an
  action in federal district court in the Northern District of California
  against the Company and PCS alleging that the Company's acquisition of PCS
  violated federal antitrust laws.  The suit seeks divestiture of PCS by the
  Company.  The Company's motion to dismiss is pending.  In October 1995,
  Pfizer, Inc. sued PCS in the New York Supreme Court for New York County
  alleging that PCS breached a 1994 rebate agreement between the companies.  The
  suit seeks injunctive relief and damages.  Pfizer's request for a preliminary
  injunction was denied and trial is scheduled to begin March 19, 1996.

       The Company is also a defendant in other litigation, including product
  liability and patent suits, of a character regarded as normal to its business.

       While it is not possible to predict or determine the outcome of the legal
  actions pending against the Company, in the opinion of the Company the costs
  associated with all such actions will not have a material adverse effect on
  its consolidated financial position or liquidity but could possibly  be
  material to the consolidated results of operations in any one accounting
  period.

  Item 4.   SUBMISSION OF MATTERS TO A VOTE OF SECURITY HOLDERS

       During the fourth quarter of 1995, no matters were submitted to a vote of
  security holders.

                                     PART II

  Item 5.   MARKET FOR THE COMPANY'S COMMON STOCK AND RELATED
            STOCKHOLDER MATTERS

       Information relating to the principal market for the Company's common
  stock and related stockholder matters, set forth in the Company's 1995 Annual
  Report under "Review of Operations--Selected Quarterly Data (unaudited)," at
  page 28 (page 15 of Exhibit 13), and "Review of Operations--Selected
  Financial Data (unaudited)," at page 29 (page 16 of Exhibit 13), is
  incorporated herein by reference.

  Item 6.   SELECTED FINANCIAL DATA

       Selected financial data for each of the Company's five most recent fiscal
  years, set forth in the Company's 1995 Annual Report under "Review of
  Operations--Selected Financial Data (unaudited)," at page 29 (page 16 of
  Exhibit 13), are incorporated herein by reference.

                                 11

  Item 7.   MANAGEMENT'S DISCUSSION AND ANALYSIS OF RESULTS OF
            OPERATIONS AND FINANCIAL CONDITION

     The following portions of the Company's 1995 Annual Report (found at pages
  1-7 and 35-37 of Exhibit 13) constitute management's discussion and analysis
  of results of operations and financial condition and are incorporated herein
  by reference:

     "Review of Operations--Strategic Actions" (page 16)
     "Review of Operations--Stock Split" (page 16)
     "Review of Operations--Operating Results of Continuing Operations and Net
       Income--1995" (pages 16, 17, 19 and 20)
     "Review of Operations--Operating Results of Continuing Operations and Net
       Income--1994" (pages 20-21)
     "Review of Operations--Financial Condition" (pages 21 and 24)
     "Review of Operations--Environmental and Legal Matters" (page 24)

  Item 8.   FINANCIAL STATEMENTS AND SUPPLEMENTARY DATA

       The consolidated financial statements of the Company and its
  subsidiaries, listed in Item 14(a)1 and included in the Company's 1995 Annual
  Report at pages 18, 22, 23, and 25 (Consolidated Statements of Income,
  Consolidated Balance Sheets, and Consolidated Statements of Cash Flows), pages
  26 and 27 (Segment Information), and pages 30-43 (Notes to Consolidated
  Financial Statements) (together, pages 9-14 and 17-32 of Exhibit 13), and the
  Report of Independent Auditors set forth in the Company's 1995 Annual Report
  at page 45 (page 34 of Exhibit 13), are incorporated herein by reference.

       Information on quarterly results of operations, set forth in the
  Company's 1995 Annual Report under "Review of Operations--Selected Quarterly
  Data (unaudited)," at page 28 (page 15 of Exhibit 13), is incorporated herein
  by reference.

  Item 9.   DISAGREEMENTS ON ACCOUNTING AND FINANCIAL DISCLOSURE

      None.

                                     PART III

  Item 10.  DIRECTORS AND EXECUTIVE OFFICERS OF THE REGISTRANT

       Information relating to the Company's directors, set forth in Section 1
  of the Company's Proxy Statement dated March 4, 1996 (the "Proxy
  Statement"), under "Nominees for Election" and "Certain Information
  Concerning Director Nominees and Directors Continuing in Office," at pages 1-
  5, is incorporated herein by reference.  Information relating to the Company's
  executive officers is set forth at pages 7-8 of this Form 10-K under
  "Executive Officers of the Company."  Information relating to certain filing
  obligations of directors and executive officers under the federal securities
  laws, set forth in the Proxy Statement under "Other Matters" at page 25, is
  also incorporated herein by reference.

                               12

  Item 11.  EXECUTIVE COMPENSATION

       Information relating to executive compensation, set forth in Section 1 of
  the Proxy Statement  under "Directors' Compensation", "Executive
  Compensation", "Compensation Committee Interlocks", "Retirement Plan" and
  "Change-in-Control Severance Pay Arrangements" at pages 7-18, is
  incorporated herein by reference, except that the Compensation and Management
  Development Committee Report and Performance Graph are not so incorporated.

  Item 12.  SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT

       Information relating to ownership of the Company's common stock by
  persons known by the Company to be the beneficial owners of more than 5% of
  the outstanding shares of common stock and by management, set forth in Section
  1 of the Proxy Statement under "Common Stock Ownership by Directors and
  Executive Officers," at page 6, and "Principal Holders of Common Stock," at
  page 7, is incorporated herein by reference.

  Item 13.  CERTAIN RELATIONSHIPS AND RELATED TRANSACTIONS

     None.

                                     PART IV

  Item 14.  EXHIBITS, FINANCIAL STATEMENT SCHEDULES, AND REPORTS ON FORM 8-K

  (a)1.     Financial Statements

       The following consolidated financial statements of the Company and its
  subsidiaries, included in the Company's 1995 Annual Report at the pages
  indicated in parentheses, are incorporated by reference in Item 8:

       Consolidated Statements of Income--Years Ended December 31, 1995, 1994,
       and 1993 (page 18) (page 9 of Exhibit 13)

       Consolidated Balance Sheets--December 31, 1995 and 1994 (pages 22-23)
       (pages 10-11 of Exhibit 13)

       Consolidated Statements of Cash Flows--Years Ended December 31, 1995,
       1994, and 1993 (page 25) (page 12 of Exhibit 13)

       Segment Information (pages 26 and 27) (pages 13-14 of Exhibit 13)

       Notes to Consolidated Financial Statements (pages 30-43) (pages 17-32 of
       Exhibit 13)

  (a)2.     Financial Statement Schedules

       The consolidated financial statement schedules of the Company and its
  subsidiaries have been omitted because they are not required, are
  inapplicable, or are adequately explained in the financial statements.

                                13

       Financial statements of interests of 50% or less, which are accounted for
  by the equity method, have been omitted because they do not, considered in the
  aggregate as a single subsidiary, constitute a significant subsidiary.

  (a)3.     Exhibits

       3.1  Amended Articles of Incorporation

       3.2  By-laws

       4.1  Form of Indenture with respect to Contingent Payment Obligation
            Units dated March 18, 1986, between Eli Lilly and Company and Harris
            Trust and Savings Bank, as Trustee

       4.2  Rights Agreement dated as of July 18, 1988, between Eli Lilly and
            Company and Bank One, Indianapolis, NA

       4.3  Form of Indenture dated as of February 21, 1989, between Eli Lilly
            and Company and Merchants National Bank & Trust Company of
            Indianapolis, as Trustee

       4.4  Form of Eli Lilly and Company Five Year Convertible Note

       4.5  Form of Indenture with respect to Debt Securities dated as of
            February 1, 1991, between Eli Lilly and Company and Citibank, N.A.,
            as Trustee

       4.6  Form of Standard Multiple-Series Indenture Provisions dated, and
            filed with the Securities and Exchange Commission on, February 1,
            1991

       4.7  Form of Indenture dated as of September 5, 1991, among the Lilly
            Savings Plan Master Trust Fund C, as Issuer; Eli Lilly and
            Company, as Guarantor; and Chemical Bank, as Trustee1

       4.8  Form of Fiscal and Paying Agency Agreement dated July 8, 1993,
            between Eli Lilly and Company and Citibank, N.A., Fiscal and Paying
            Agent, including forms of Notes, relating to 5-1/2% Notes Due 19981

       4.9  Form of Fiscal and Paying Agency Agreement dated February 7, 1995,
            between Eli Lilly and Company and Citibank, N.A., Fiscal and Paying
            Agent, including forms of Notes, relating to 8-1/8% Notes Due
            February 7, 20001

       4.10 Form of Fiscal and Paying Agency Agreement dated February 7, 1995,
            between Eli Lilly and Company and Citibank, N.A., Fiscal and Paying
            Agent, including forms of Notes, relating to 8-3/8% Notes Due
            February 7, 20051

       10.1 1984 Lilly Stock Plan, as amended2

- ---------------
1 These exhibits are not filed with this Report.  Copies will be furnished
  to the Securities and Exchange Commission upon request.
2 Indicates management contract or compensatory plan.

                             14

       10.2 1989 Lilly Stock Plan, as amended2

       10.3 1994 Lilly Stock Plan2

       10.4 The Lilly Deferred Compensation Plan, as amended2

       10.5 The Lilly Directors' Deferral Plan, as amended2

       10.6 The Eli Lilly and Company EVA Bonus Plan, as amended2

       10.7 Eli Lilly and Company Change in Control Severance Pay Plan for
            Select Employees2

       10.8 Letter Agreement dated September 3, 1993, between the Company and
            Vaughn D. Bryson2

       11.  Computation of Earnings Per Share on Primary and Fully Diluted Bases

       12.  Computation of Ratio of Earnings to Fixed Charges

       13.  Annual Report to Shareholders for the Year Ended December 31, 1995
            (portions incorporated by reference into this Form 10-K)

       21.  List of Subsidiaries

       23.  Consent of Independent Auditors

       27.  Financial Data Schedule

       99.  Report to Holders of Eli Lilly and Company Contingent Payment
            Obligation Units

  (b)  Reports on Form 8-K

       On October 2, 1995, the Company filed a Form 8-K reporting the completion
  of its exchange offer pursuant to which holders of the Company's common stock
  exchanged 16,504,298 shares of such stock for all 57,600,000 shares of the
  common stock of Guidant Corporation owned by the Company.


- ---------------
  2 Indicates management contract or compensatory plan.

                             15


                                    SIGNATURES

       Pursuant to the requirements of Section 13 or 15(d) of the Securities
  Exchange Act of 1934, the Registrant has duly caused this report to be signed
  on its behalf by the undersigned thereunto duly authorized.

                                ELI LILLY AND COMPANY


                                By s/Randall L. Tobias
                                   --------------------------------
                                  (Randall L. Tobias, Chairman of the Board
                                      and Chief Executive Officer)

                                                     March 18, 1996


       Pursuant to the requirements of the Securities Exchange Act of 1934, this
  report has been signed below on March 18, 1996 by the following persons on
  behalf of the Registrant and in the capacities indicated.

       SIGNATURE                              TITLE
  ------------------------------------------------------------------------

  s/Randall L. Tobias           Chairman of the Board, Chief Executive Officer,
  -------------------------     and a Director (principal executive officer)
  (RANDALL L. TOBIAS)

  s/Charles E. Golden           Executive Vice President, Chief Financial
  -------------------------     Officer, and a Director (principal 
  (CHARLES E. GOLDEN)           financial officer)

  s/Arnold C. Hanish            Chief Accounting Officer
  -------------------------     (principal accounting officer)
  (ARNOLD C. HANISH)  

  s/Steven C. Beering, M.D.        Director
  -------------------------
  (STEVEN C. BEERING, M.D.)

  s/James W. Cozad                 Director
  -------------------------
  (JAMES W. COZAD)

  s/Karen N. Horn                  Director
  -------------------------
  (KAREN N. HORN, Ph.D.)

  s/Alfred G. Gilman, M.D., Ph.D.  Director
  -------------------------------
  (ALFRED G. GILMAN, M.D., Ph.D.)

                             16


       SIGNATURE                              TITLE
  ----------------------------------------------------------------------


  s/J. Clayburn La Force, Jr., Ph.D.      Director
  ----------------------------------
  (J. CLAYBURN LA FORCE, JR., Ph.D.)

                                          Director
  -------------------------
  (KENNETH L. LAY, Ph.D.)

  s/Franklyn G. Prendergast, M.D., Ph.D.  Director
  --------------------------------------
  (FRANKLYN G. PRENDERGAST, M.D., Ph.D.)

  s/Kathi P. Seifert                      Director
  -------------------------
  (KATHI P. SEIFERT)

  s/Sidney Taurel                         Director
  -------------------------
  (SIDNEY TAUREL)

  s/August M. Watanabe, M.D.              Director
  --------------------------
  (AUGUST M. WATANABE, M.D.)

  s/Alva O. Way                           Director
  -------------------------
  (ALVA O. WAY)

                            17



                                                                      TRADEMARKS

                                            ApralanR (apramycin sulfate, Elanco)
                                                       AxidR (nizatidine, Lilly)
                                                       CeclorR (cefaclor, Lilly)
                                                CobanR (monensin sodium, Elanco)
                       CompudoseR (estradiol controlled-release implant, Elanco)
                  Darvocet-NR (propoxyphene napsylate with acetaminophen, Lilly)
                                     DobutrexR (dobutamine hydrochloride, Lilly)
                                                 DynabacR (dirithromycin, Lilly)
                                            EldisineR (vindesine sulfate, Lilly)
                                      GemzarR (gemcitabine hydrochloride, Lilly)
                                               HumalogTM (insulin lispro, Lilly)
                        HumatropeR (somatropin of recombinant DNA origin, Lilly)
                       HumulinR (human insulin of recombinant DNA origin, Lilly)
                                                        lletinR (insulin, Lilly)
                                                     KeflexR (cephalexin, Dista)
                                       KeftabR (cephalexin hydrochloride, Dista)
                                             KefuroxR (cefuroxime sodium, Lilly)
                                               KefzolR (cefazolin sodium, Lilly)
                                                    LorabidR (loracarbef, Lilly)
                                             MandolR (cefamandole nafate, Lilly)
                                      MaxibanR (narasin and nicarbazine, Elanco)
                                       IMS MEDACOMR (Integrated Medical Systems)
                                         MicotilR (tilmicosin phosphate, Elanco)
                                                     MontebanR (narasin, Elanco)
                                             NebcinR (tobramycin sulfate, Lilly)
                                           OncovinR (vincristine sulfate, Lilly)
                                             PermaxR (pergolide mesylate, Lilly)
                                       ProzacR (fluoxetine hydrochloride, Dista)
                                                                    RECAPR (PCS)
                                                    ReoProTM  (abciximab), Lilly
                                             RumensinR (monensin sodium, Elanco)
                                                  TazidimeR (ceftazidime, Lilly)
                                                        TylanR (tylosin, Elanco)
                                     VancocinR (vancomycin hydrochloride, Lilly)
                                            VelbanR (vinblastine sulfate, Lilly)


            THE LILLY DIRECTORS' DEFERRAL PLAN
            (As amended and restated through February 1, 1996)


Section 1. Establishment of the Plan.
- -------------------------------------
    Effective January 1, 1996, there is hereby established a plan whereby
    certain Directors of the Company who are not current salaried employees
    of the Company may voluntarily defer compensation (the "Deferred
    Compensation" portion of the Plan), and certain Directors of the Company
    who are not current or former full-time salaried employees of the Company
    can share in the long-term growth of the Company by acquiring an
    ownership interest in the Company (the "Deferred Stock" portion of the
    Plan).  Prior to January 1, 1996, the Company maintained the Deferred
    Compensation portion of the Plan and the Deferred Stock portion of the
    Plan as two separate plans, The Lilly Directors' Deferred Compensation
    Plan and The Lilly Non-Employee Directors' Deferred Stock Plan,
    respectively (the "Prior Plans").  The Plan is deemed to consist of the
    amounts held under the Prior Plans, and any election made by a Director
    under the Prior Plans, unless and until amended by the Director in
    accordance with this Plan, shall remain in effect under this Plan.
     
 Section 2. Definitions.
 -----------------------
    When used in the Plan, the following terms shall have the definitions set
    forth in this Section 2:

    2.1.  Accrual Date.  The term "Accrual Date" means the first day in
    ----  ------------
    December of each calendar year on which the common stock of the
    Company is traded, or such other annual date, not earlier than the third
    Monday in February, established by the Committee as the date as of which
    Shares are allocated to each Share Account.
    
    2.2.  Beneficiary.  The term "Beneficiary" means the beneficiary or
    ----  -----------
    beneficiaries (including any contingent beneficiary or beneficiaries)
    designated pursuant to subsection 8.3 hereof.
   
    2.3.  Board of Directors.  The term "Board of Directors" means the
    ----  ------------------
    Board of Directors of the Company.
    
                                       2

    2.4.  Committee.  The term "Committee" refers to the Compensation and
    ----  ---------
    Management Development Committee of the Board of Directors, provided
    that no Participant shall be considered to be a member of the Committee
    for purposes of the Plan.
   
    2.5.  Company.  The term "Company" means Eli Lilly and Company.
    ----  -------

    2.6.  Company Credit.  The term "Company Credit" means an amount
    ----  --------------
    computed, and credited annually to a Participant's Deferred Compensation
    Account at a rate that is two percent (2%) above the rate that the
    Treasurer of the Company determines was the prime rate ofinterest
    charged by Chemical Bank, New York, New York (the "Bank"), on loans made
    on the immediately preceding December 15 or, if the Bank was closed on
    December 15, the last day preceding December 15 on which the Bank was
    open for business.
   
    2.7.  Compensation.  The term "Compensation" means the retainer and the
    ----  ------------
    aggregate of all meeting fees to which a Director is entitled for
    services rendered to the Company as a Director.
     
                              3

    2.8.  Deferral Allocation Date.  The term "Deferral Allocation Date"
    ----  ------------------------
    means the third Monday of any month, or if Shares are not traded on
    The New York Stock Exchange on such third Monday of the month, the last
    day before the third Monday of the month on which Shares are traded on
    The New York Stock Exchange, that follows the earlier of (a) the date
    on which an amount deferred under the Plan would have been paid in cash
    if a deferral election had not been made hereunder, or (b) in the case
    of an award of compensation which by its terms is subject to a deferred
    payment date, the date of award.
   
    2.9.  Deferred Amount.  The term "Deferred Amount" means the amount of a
    ----  ---------------
    Deferred Compensation Participant's Compensation that the Participant
    elects to defer in accordance with Section 4 hereof.

    2.10.  Deferred Compensation Participant.  The term "Deferred Compensation
    -----  ---------------------------------
    Participant" means a Director who is not a salaried employee of the
    Company and who has elected to defer all or part of his Compensation
    pursuant to the Plan in accordance with Section 4 hereof.
    
    2.11.  Deferred Stock Participant.  The term "Deferred Stock Participant"
    -----  --------------------------
    means a Director who is not a current or former full-time salaried
    employee of the Company and who becomes a Participant in the Plan in
    accordance with Section 3 hereof.

                              4
   
    2.12.  Director.  The term "Director" means each member of the Board of
    -----  --------
    Directors.
    
    2.13.  Dividend Allocation Date.  The term "Dividend Allocation Date"
    -----  ------------------------
    means the first Monday that (a) follows a Dividend Payment Date and
    (b) is the third Monday of a Month.
                   
    2.14.  Dividend Payment Date.  The term "Dividend Payment Date" means the
    -----  ---------------------
    date as of which the Company pays a cash dividend on Shares.

    2.15.  Dividend Record Date.  The term "Dividend Record Date" means,
    -----  --------------------
    with respect to any Dividend Payment Date, the date established by the
    Board of Directors as the record date for determining shareholders
    entitled to receive payment of the dividend.

    2.16.  Individual Accounts.  The term "Individual Accounts" or 
    -----  -------------------
    "Accounts" means the separate accounts (the Deferred Compensation
    Account and the Share Account), described in Section 7 hereof, one or
    both of which is established under the Plan for each Participant.  When
    used in the singular, the term shall refer to one of these two accounts,
    as the context requires.

                           5
    
    2.17.  Participant.  The term "Participant" means a Director who is a
    -----  -----------
    Deferred Stock Participant, a Deferred Compensation Participant, or both,
    as the case may be.
   
    2.18.  Plan.  The term "Plan" means The Lilly Directors' Deferral Plan,
    -----  ----
    as set forth herein and as it may be amended from time to time.

    2.19.  Share.  The term "Share" means a share of common stock of the
    -----  ------
    Company.
            
    Section 3. Deferred Stock Participants.
    --------------------------------------
          
    Each Director who participated in The Lilly Non-Employee Directors'
    Deferred Stock Plan immediately before the effective date of this Plan
    shall continue as a Deferred Stock Participant on such effective date,
    and all elections in effect under The Lilly Non-Employee Directors'
    Deferred Stock Plan shall remain in effect under this Plan, unless and
    until amended in accordance with this Plan.  Each person who is

                             6

    thereafter elected or appointed as a Director, and who is not and has
    never been a full-time salaried employee of the Company, shall become a
    Deferred Stock Participant beginning with the month in which such
    Director takes office.  A Deferred Stock Participant shall cease to
    participate in the Plan when the Participant ceases to be a Director.
    For purposes of the Plan, a Deferred Stock Participant shall be deemed to
    cease to be a Director on the first day of the month next following the
    month in which he last serves as a Director.
           
    Section 4.  Deferred Compensation Participants.
    ----------------------------------------------
     
    Each Director who participated in The Lilly Directors' Deferred
    Compensation Plan immediately before the effective date of the Plan shall
    continue as a Deferred Compensation Participant on such effective date,
    and all elections in effect under The Lilly Directors' Deferred
    Compensation Plan shall remain in effect under this Plan, unless and
    until amended in accordance with this Plan.  Prior to the beginning of
    each calendar year, any Director who is not a salaried employee of the
    Company may defer the receipt of Compensation to be earned by the
    Director during such year by filing with the Company a written election
    that:
   
                              7

        (i)  defers payment of a designated amount (of one Thousand
             Dollars ($1,000) or more) or percentage of his
             Compensation for services attributable to the following
             calendar year or portion thereof (the "Deferred Amount");
                      
       (ii)  specifies the payment option selected by the Participant
             pursuant to subsection 8.2 hereof for such Deferred Amount; and

       (iii) specifies the option selected by the Participant pursuant
             to Section 5 hereof for such Deferred Amount.
            
    The amount deferred may not exceed the Director's Compensation for the
    calendar year.  Notwithstanding the foregoing, any individual who is
    newly elected or appointed to serve as a Director may, not later than
    thirty (30) days after his election or appointment becomes effective,
    elect in accordance with the preceding provisions of this Section 4, to
    defer the receipt of Compensation earned during the portion of the
    current calendar year that follows the filing of the election with the
    Company.  Except as provided in subsections 8.2 and 8.4 hereof, any
    elections made pursuant to this Section 4 with respect to a calendar
    year shall be irrevocable when made.  If a Participant fails to make an

                                8

    election under section 5 with respect to his Deferred Amount for a
    future calendar year, the Participant's previous election shall remain
    in effect, provided that the Participant may amend his election with
    regard to a future calendar year at any time.
            
    Section 5.  Form of Deferred Compensation Credits.
    -------------------------------------------------

    5.1.  Deferred Compensation Account.  Except with respect to the
    ----  -----------------------------
    deferral of Compensation for a calendar year in which a Deferred
    Compensation Participant elects to have all or a percentage of the
    Deferred Amount credited in Shares in accordance with subsection 5.2
    hereof, the Deferred Amount shall be denominated in U.S. dollars and
    credited to the Participant's Deferred Compensation Account pursuant to
    subsection 7.1 hereof.
          
    5.2.  Shares.  Prior to the beginning of each calendar year, a Deferred
    ----  ------
    Compensation Participant may elect to have all or a percentage of the
    Deferred Amount for the following calendar year credited in Shares and 
    allocated to the Participant's Share Account pursuant to subsection
    7.2 hereof.

                            9

    5.3.  Transfer of Deferred Compensation Account Balance to Share Account.
    ----  ------------------------------------------------------------------
    Prior to the effective date of the Plan, a Deferred Compensation
    Participant may elect to have all or a portion of his final credited
    account balance in The Lilly Directors' Deferred Compensation Plan
    converted to Shares and credited to the Participant's Share Account.
    Such conversion shall take place as of January 1, 1996 based upon the
    combined average of the high and low prices of Shares on The New York
    Stock Exchange on each of the last five (5) days of 1995 on which Shares
    are traded on The New York Stock Exchange.  Such conversion shall,
    however, be contingent upon receipt by the Company of (a) a no-action
    letter from the Securities and Exchange Commission ("EC"), or (b) an
    opinion of counsel satisfactory to the Company, to the effect that
    such conversion shall not disqualify the participate from being a "is
    interested person" within the meaning of prior SEC Rule 16b-3(d)(3)
    and new SEC Rule 16b-3(c)(2)(i) for purposes of administering the
    Company's employee stock incentive plans.

    Section 6.  Allocations to Share Accounts.
    -----------------------------------------

    6.1.  Allocation of Shares.  As of the Accrual Date of each calendar
    ----  --------------------
    year, there shall be allocated to the Share Account of each Deferred
    
                            10
 
    Stock Participant, as part of the compensation to such Deferred
    Stock Participant for service on the Board of Directors, eight hundred
    (800) Shares, or, if less, the number of Shares that could be purchased
    with the Participant's Compensation for the calendar year, assuming
    attendance at eight one-day meetings, at the average of the high and low
    prices of Shares on The New York Stock Exchange on the Accrual Date.
    Shares allocated to each Deferred Stock Participant's Share Account shall
    be hypothetical and not issued or transferred by the Company until
    payment is made pursuant to Section 8 hereof.
    
    6.2.  Special Allocation.  As of February 1, 1996, there shall be
    ----  ------------------
    allocated to the Share Account of each Deferred Stock Participant the
    number of Shares having a market value (calculated as set forth below)
    equal to the present value as of December 31, 1995 of the accrued benefit
    of the Participant in The Lilly Non-Employee Directors' Retirement Plan,
    whether or not such Participant was vested in such benefit on that date.
    Such present value calculation shall be performed by the Company in its
    discretion and shall be converted to Shares based upon the combined
    average of the high and low prices of Shares on The New York Stock
    Exchange on each of the last five (5) days preceding February 1, 1996 on
    which Shares are traded on The New York Stock Exchange.  Such conversion
    shall, however, be contingent upon receipt by the Company of (a) a

                               11

    no-action letter from the Securities and Exchange Commission ("EC"), or
    (b) an opinion of counsel satisfactory to the Company, to the effect that
    such conversion shall not disqualify the participate from being a "is
    interested person" within the meaning of prior SEC Rule 16b-3(d)(3) and
    new SEC Rule 16b-3(c)(2)(i) for purposes of administering the Company's
    employee stock incentive plans.
    
    Section 7.  Individual Accounts.
    -------------------------------
   
    The Company shall maintain Individual Accounts for Participants, as
    follows:
   
    7.1.  Deferred Compensation Account.  The Company shall maintain a
    ----  -----------------------------
    Deferred Compensation Account in the name of each Deferred Compensation
    Participant in respect of each calendar year the Deferred Compensation
    Participant elects to defer the receipt of Compensation pursuant to
    Section 4 hereof and does not elect to have the Deferred Amount for such
    calendar year credited in Shares pursuant to subsection 5.2 hereof.  The
    opening balance of each Deferred Compensation Account on January 1, 1996
    shall be equal to the closing balance on December 31, 1995 of the
   
                            12

    corresponding account maintained under The Lilly Directors' Deferred
    Compensation Plan, less any portion of such account converted to Shares and
    allocated to the Participant's Share Account pursuant to subsection 5.3
    hereof.  The Deferred Compensation Account shall be denominated in U.S.
    dollars, rounded to the nearest whole cent.  A Deferred Amount allocated
    to a Deferred Compensation Account pursuant to subsection 5.1 hereof
    shall be credited to the Deferred Compensation Account as of the Deferral
    Allocation Date.
   
    7.2.  Share Account.  The Company shall maintain a Share Account for each
    ----  -------------
    Deferred Stock Participant and for each Deferred Compensation Participant
    who elects to have a Deferred Amount credited in Shares pursuant to
    subsection 5.2 hereof, or who elects to convert all or a portion of his
    final account balance under The Lilly Directors' Deferred Compensation
    Plan to Shares pursuant to subsection 5.3 hereof.  The opening balance of
    each Share Account on January 1, 1996, shall be equal to the closing
    balance on December 31, 1995, of the corresponding Share Account
    maintained under The Lilly Non-Employee Directors' Deferred Stock Plan.
    The Share Account shall be denominated in Shares, and shall be maintained
    in fractions rounded to three (3) decimal places.
                
                              13

    Shares allocated to a Deferred Compensation Participant's Share Account
    in accordance with the Participant's election under subsection 5.2 hereof
    shall be credited to the Participant's Share Account as of the Deferral
    Allocation Date.  Shares and, if necessary, fractional Shares, shall be
    credited to a Participant's Share Account based upon the average of the
    high and low price of Shares on The New York Stock Exchange on the
    Deferral Allocation Date.
             
    7.3.  Former Interest Account.  All balances in the Account known
    ----  -----------------------
    previously as the "Interest Account" under The Lilly NonEmployee
    Directors' Deferred Stock Plan shall be transferred to the Share Account
    effective on January 1, 1996, utilizing the same price of Shares set
    forth in subsection 5.3 hereof for purposes of the calculation.
    
    7.4.  Accrual of Company Credit.  The Treasurer of the Company shall
    ----  -------------------------
    determine the annual rate of Company Credit on or before December 31 of
    each calendar year.  This rate shall be effective for the following
    calendar year.  The Company Credit shall accrue monthly, at one-twelfth
    of the applicable annual rate, on all amounts credited to a Participant's
    Deferred Compensation Account, including the Company Credits for prior
   
                               14

    years.  The Company Credit shall not accrue on any amount distributed to
    a Participant (or to the Participant's Beneficiary) during the month for
    which the accrual is determined, except where an amount is distributed to
    a Beneficiary in the month of the Participant's death.  The Company
    Credit for each year shall be credited to each Deferred Compensation
    Account as of December 31 of that year and shall be compounded monthly.
                
    7.5.  Cash Dividends.  Cash dividends paid on Shares shall be deemed to
    ----  --------------
    have been paid on the Shares allocated to each Participant's Share
    Account as if the allocated Shares were actual Shares issued and
    outstanding on the Dividend Record Date.  An amount equal to the amount
    of such dividends shall be credited in Shares to each Share Account as of
    each Dividend Allocation Date based upon the average of the high and low
    prices for Shares on The New York Stock Exchange on the Divided
    Allocation Date, or, if Shares are not traded on the Divided Allocation
    Date, the next day on which Shares are traded.
                
    7.6.  Capital Adjustments.  The number of Shares referred to in Section 6
    ----  -------------------
    hereof and the number of Shares allocated to each Share Account shall be
    adjusted by the Committee, as it deems appropriate, to reflect stock
    dividends, stock splits, reclassifications, spinoffs, and other

                             15

    extraordinary distributions, as if those Shares were actual Shares.
                       
    7.7.  Account Statements.  Within a reasonable time following the end of
    ----  ------------------
    each calendar year, the Company shall render an annual statement to each
    Participant.  The annual statement for each Deferred Stock Participant
    shall report the number of Shares credited to the Participant's Share
    Account as of December 31 of that year.  The annual statement for each
    Deferred Compensation Participant shall report the dollar amount credited
    to the Participant's Deferred Compensation Account as of December 31 of
    that year, and, if the Deferred Compensation Participant elects to invest
    a Deferred Amount in Shares pursuant to subsection 5.2 hereof, or if the
    Deferred Compensation Participant elects to convert his final account
    balance under The Lilly Directors' Deferred Compensation Plan to Shares
    pursuant to subsection 5.3 hereof, the number of Shares credited to the
    Participant's Share Account as of December 31 of that year.
          
    Section 8.  Payment Provisions.
    ------------------------------
   
    8.l.  Method of Payment.  All payments to a Participant (or to a
    ----  -----------------
    Participant's Beneficiary) with respect to the Participant's Deferred
   
                            16

    Compensation Account shall be paid in cash.  All payments to a
    Participant (or to a Participant's Beneficiary) with respect to the
    Participant's Share Account shall be paid in Shares, at which time the
    Shares shall be issued or transferred on the books of the Company.  All
    Shares to be transferred hereunder shall be transferred out of treasury
    shares to the extent available.  Fractional Shares shall not be
    transferred to a Participant, provided that in the case of a final
    payment under the Plan with respect to a Participant, any fractions
    remaining in the Participant's Share Account shall be rounded up to the
    next whole Share and that number of whole Shares shall be transferred to
    the Participant (or, after the Participant's death, to the Participants's
    Beneficiary).  If Shares are not traded on The New York Stock Exchange on
    any day on which a payment of Shares is to be made under the Plan, then
    that payment shall be made on the next day on which Shares are traded on
    The New York Stock Exchange.
    
    8.2.  Payment Options.  Prior to each calendar year, or within 30 days
    ----  ---------------
    after becoming a Participant, the Participant shall select a payment
    election with respect to the payment of any one or all of the
    Participant's Individual Accounts from the following payment elections:

                               17

          (i)  a lump sum in January of the calendar year immediately
               following the calendar year in which the Participant ceases
               to be a Director; or
              
         (ii)  annual (or, in the case of the Deferred Compensation
               Account only, monthly) installments over a period of two to ten
               years commencing in January of the calendar year following the
               calendar year during which the Participant ceases to be a
               Director.
              
    If the payment option described in paragraph (i), above, has been
    elected, the amount of the lump sum with respect to the Participant's
    Deferred Compensation Account shall be equal to the amount credited to
    the Participant's Deferred Compensation Account as of the December 31
    next preceding the date of the payment, and the amount of the lump sum
    with respect to the Participant's Share Account shall be equal to the
    number of Shares credited to the Share Account as of the December 31 next
    preceding the date of payment.  If the payment option described in
    paragraph (ii), above, has been elected, the amount of each installment
    with respect to the Participant's Deferred Compensation Account shall be
    equal to the amount credited to the Participant's Deferred Compensation
    Account as of the last day of the month next preceding the date of a
    
                              18

    monthly installment payment, or the December 31 next preceding the date
    of an annual installment payment, divided by the number of installment
    payments that have not yet been made.  The amount of each installment
    with respect to the Participant's Share Account shall be equal to the
    number of Shares credited to the Participant's Share Account as of the
    December 31 next preceding the date of an annual installment payment,
    divided by the number of installment payments that have not yet been made.
    A Participant may elect that his final payment election may control
    over all prior payment elections.  If the Participant fails to elect a
    payment option, the amount credited to the Participant's Individual
    Account shall be distributed in a lump sum in accordance with the payment
    option described in paragraph (i), above.  If the amount credited to a
    Participant's Deferred Compensation Account or the value of Shares
    credited to a Participant's Share Account is less than $25,000, the
    Committee, in its sole discretion, may pay out the amount credited to the
    Participant's Individual Account in a lump sum.
   
    8.3.  Payment Upon Death.  Within a reasonable period of time following
    ----  ------------------
    the death of a Participant, the amount credited to a Participant's
    Deferred Compensation Account and all of the Shares credited to the
   
                             19

    Participant's Share Account shall be paid by the Company in a lump sum
    to the Participant's Beneficiary. For purposes of this subsection 8.3,
    the amount credited to the Participant's Deferred Compensation Account
    and the number of Shares credited to the Participant's Share Account
    shall be determined as of the date of payment.  A Participant may
    designate the Beneficiary, in writing, in a form acceptable to the
    Committee before the Participant's death.  A Participant may, before the
    Participant's death, revoke a prior designation of Beneficiary and may
    also designate a new Beneficiary without the consent of the previously
    designated Beneficiary, provided that such revocation and new designation
    (if any) are in writing, in a form acceptable to the Committee, and filed
    with the Committee before the Participant's death.  If the Participant
    does not designate a Beneficiary, or if no designated Beneficiary
    survives the Participant, any amount not distributed to the Participant
    during the Participant's life shall be paid to the Participant's estate
    in a lump sum in accordance with this subsection 8.3.
                 
    8.4.   Payment on Unforeseeable Emergency.  The Administrator may, in
    ----   ----------------------------------
    its sole discretion, direct payment to a Participant of all or of any
    portion of the Participant's Individual Account balance, notwithstanding
    an election under subsection 8.2 above, at any time that it determines
   
                          20

    that such Participant has an unforeseeable emergency, and then only to
    the extent reasonably necessary to meet the emergency.  For purposes of
    this section, "unforeseeable emergency" means severe financial hardship
    to the Participant resulting from a sudden and unexpected illness or
    accident of the Participant or of a dependent of the Participant, loss
    of the Participant's property due to casualty, or other similar
    extraordinary and unforeseeable circumstances arising as a result of
    events beyond the control of the Participant.  The circumstances that
    will constitute an unforeseeable emergency will depend upon the facts of
    each case, but, in any case, payment may not be made to the extent that
    such hardship is, or may be, relieved --
            
       (i)  Through reimbursement or compensation by insurance or
            otherwise,
  
      (ii)  By liquidation of the Participant's assets, to the extent the
            liquidation of such assets would not itself cause severe
            financial hardship, or
            
     (iii)  By cessation of deferrals under the Plan.

                                21

    Examples of what are not considered to be unforeseeable emergencies
    include the need to send a Participant's child to college or the desire
    to purchase a home.
    
    Section 9.  Ownership of Shares.
    -------------------------------

    A Participant shall have no rights as a shareholder of the Company with
    respect to any Shares until the Shares are transferred to the Participant
    on the books of the Company.
    
    Section 10.  Prohibition Against Transfer.
    -----------------------------------------

    The right of a Participant to receive payments of Shares and cash under
    the Plan may not be transferred except by will or applicable laws of
    descent and distribution.  A Participant may not assign, sell, pledge, or
    otherwise transfer Shares or cash to which he is entitled hereunder prior
    to transfer or payment thereof to the Participant.
    
    Section 11.  General Provisions.
    -------------------------------

                            22
   
    11.1.  Director's Rights Unsecured.  The Plan is unfunded.  The right
    -----  ---------------------------
    of any Participant to receive payments of cash or Shares under
    the provisions of the Plan shall be an unsecured claim against the
    general assets of the Company.

    11.2.  Administration.  Except as otherwise provided in the Plan, the
    -----  --------------
    Plan shall be administered by the Committee, which shall have the
    authority to adopt rules and regulations for carrying out the Plan,
    and which shall interpret, construe, and implement the provisions of the
    Plan.
         
    11.3.  Legal Opinions.  The Committee may consult with legal counsel,
    -----  --------------
    who may be counsel for the Company or other counsel, with respect to its
    obligations and duties under the Plan, or with respect to any action,
    proceeding, or any questions of law, and shall not be liable with
    respect to any action taken, or omitted, by it in good faith pursuant to
    the advice of such counsel.
   
    11.4.  Liability.  Any decision made or action taken by the Board of
    -----  ---------
    Directors, the Committee, or any employee of the Company or any of its 
    subsidiaries, arising out of or in connection with the construction,

                            23

    administration, interpretation, or effect of the Plan, shall be
    absolutely discretionary, and shall be conclusive and binding on all
    parties.  Neither the Committee nor a member of the Board of Directors
    and no employee of the Company or any of its subsidiaries shall be liable
    for any act or action hereunder, whether of omission or commission, by
    any other member or employee or by any agent to whom duties in connection
    with the administration of the Plan have been delegated or, except in
    circumstances involving bad faith, for anything done or omitted to be
    done.
       
    11.5.  Withholding.  The Company shall have the right to deduct from all
    -----  -----------
    payments hereunder any taxes required by law to be withheld from such
    payments.  The recipients of such payments shall bear all taxes on
    amounts paid under the Plan to the extent that no taxes are withheld
    thereon, irrespective of whether withholding is required.
         
    11.6.  Incapacity.  If the Committee determines that any person entitled
    -----  ----------
    to benefits under the Plan is unable to care for his or here affairs
    because of illness or accident, any payment due (unless a duly qualified
    guardian or other legal representative has been appointed) may be paid
    for the benefit of such person to such person's spouse, parent, brother,
    sister, or other party deemed by the Committee to have incurred expenses
    for such person.

                             24
   
    11.7.  Inability to Locate.  If the Committee is unable to locate a
    -----  -------------------
    person to whom a payment is due under the plan for a period of twelve
    (12) months, commencing with the first day of the month as of which the
    payment becomes payable, the total amount payable to such person shall
    be forfeited.
   
    11.8.  Legal Holidays.  If any day on (or on or before) which action
    -----  --------------
    under the Plan must be taken falls on a Saturday, Sunday, or legal
    holiday, such action may be taken on (or on or before) the next
    succeeding day that is not a Saturday, Sunday, or legal holiday;
    provided, that this subsection 11.8 shall not permit any action that must
    be taken in one calendar year to be taken in any subsequent calendar
    year.
   
    Section 12.  Amendment, Suspension, and Termination.
    ---------------------------------------------------
           
    The Board of Directors shall have the right at any time, and from time
    to time, to amend, suspend, or terminate the Plan, provided that no
    
                            25

    amendment or termination shall reduce the number of Shares or the cash
    balance in an Individual Account, and provided further that the number of
    Shares allocated annually pursuant to Section 6 hereof may not be changed
    more frequently than every calendar year.

    Section 13.  Applicable Law.
    ---------------------------
            
    The Plan shall be governed by, and construed in accordance with, the
    laws of the State of Indiana, except to the extent that such laws are
    preempted by Federal law.
  
    Section 14.  Effective Date.
    ---------------------------


    The effective date of this Plan is January 1, 1996.  Nothing herein shall
    invalidate or adversely affect any previous election, designation,
    deferral, or accrual in accordance with the terms of The Lilly Directors'
    Deferred Compensation Plan or The Lilly Non-Employee Directors' Deferred
    Stock Plan that were in effect prior to the effective date of this Plan.


                        Eli Lilly and Company EVA Bonus Plan



                                      ARTICLE I

                     Bonus Plan Statement of Purpose and Summary
                     -------------------------------------------


            1.1  The purpose of the Plan is to provide a system of bonus
                 compensation for certain executive, management and
                 technical personnel of Eli Lilly and Company and
                 subsidiaries which will promote the maximization of
                 shareholder value over the long term, by linking
                 performance incentives to increases in shareholder
                 value.  The Plan ties bonus compensation to Economic
                 Value Added ("EVA"), and thereby rewards employees for
                 long-term, sustained improvement in shareholder value.

            1.2  EVA will be used as the performance measure of value
                 creation.  EVA reflects the benefits and costs of
                 capital employment.  Employees create economic value
                 when the operating profits from a business exceed the
                 cost of the capital employed.


                                     ARTICLE II

                            Definitions of Certain Terms
                            ----------------------------


            Unless the context requires a different meaning, the
            following terms shall have the following meanings:

            2.1  "Company" means Eli Lilly and Company and its
                  -------
                 subsidiaries.

            2.2  "Committee" means the Compensation and Management
                  ---------
                 Development Committee, the members of which shall be
                 selected by the Board of Directors from among its
                 members.

            2.3  "Participant" means an executive, management or
                  -----------
                 technical employee of the Company designated by the
                 Committee as a participant in the Plan with respect to
                 any Plan Year.  In its discretion, the Committee may
                 designate Participants either on an individual basis or
                 by determining that all employees in specified job
                 categories, classifications or levels shall be
                 Participants.

            2.4  "Plan" means this Eli Lilly and Company EVA Bonus Plan.
                  ----

            2.5  "Plan Year" means the applicable calendar year.
                  ---------

            2.6  "Retirement" means the cessation of employment upon the
                  ----------
                 attainment of at least eighty age and service points,
                 as determined by the provisions of The Lilly Retirement
                 Plan as amended from time to time, assuming eligibility
                 to participate in that plan.

            2.7  "Disability" means the time at which a Participant
                  ----------
                 becomes eligible for a payment under The Lilly Extended
                 Disability Plan, assuming eligibility to participate in
                 that plan.



                                     ARTICLE III
                                     -----------

                          Definition and Components of EVA
                          --------------------------------


            The following terms set forth the calculation of EVA and the
            components of calculating EVA.  The calculation of EVA for a
            Plan Year is used in determining the bonuses earned by
            Participants under the Plan, as set forth in Article IV.

            3.1  "Economic Value Added" or "EVA" means the excess NOPAT
                  -----------------------------
                 that remains after subtracting the Capital Charge.

            3.2  "Net Operating Profit After Tax" or "NOPAT'' means the
                  -------------------------------------------
                 after tax operating earnings of the Company for the
                 Plan Year. NOPAT is determined by adding net sales plus
                 other income (excluding interest income from
                 operational cash) and subtracting the following:  cost
                 of goods sold, selling, general and administrative
                 expenses (excluding goodwill amortization and interest
                 expense), amortization of research and development,
                 taxes (excluding the tax benefit of net interest
                 expense) and amounts associated with discontinued
                 operations.


            3.3  Capital Charge" means the deemed opportunity cost of
                 --------------
                 employing Capital for the Company.  The Capital Charge
                 is calculated by multiplying Capital times Cost of
                 Capital (C*).

            3.4  "Capital" means the net investment employed in the
                  -------
                 operations of the Company produced by operations and
                 financing activities.  Capital  is calculated by adding
                 together current assets (excluding operating cash), net
                 property, plant and equipment, gross goodwill, net
                 intangibles, other assets, capitalized research and
                 development, and the present value of operating leases,
                 and subtracting the following:  non-interest bearing
                 liabilities and capital associated with discontinued
                 operations.

            3.5  "Cost of Capital" or "C*" is the percentage calculated
                  -----------------------
                 from the weighted average of Cost of Debt and Cost of
                 Equity.  Cost of Capital for each Plan Year is
                 determined by reference to the percentage calculated at
                 the end of October of the prior Plan Year.

                     Cost of Debt capital is the marginal long-term
                     borrowing rate of the Company times (one minus the
                     tax rate).  Cost of Equity capital is the risk-free
                     rate plus (beta times the market risk premium).


                                     ARTICLE IV

                     Definition and Computation of the EVA Bonus
                     -------------------------------------------


            Bonuses earned under the Plan for a Plan Year are determined
            based on a comparison of actual EVA to the "Target EVA" for
            the year, which is established as described below to ensure
            improvement in EVA from year to year.  The result of this
            comparison is adjusted by a "Leverage Factor" measuring the
            volatility of industry returns.  The factor produced is
            referred to as the "Bonus Multiple," which is multiplied by
            the Participant's "Target Bonus" amount established for the
            year to produce the actual bonus earned.  This amount,
            referred to as the "Declared Bonus," is credited to the
            Participant's "Bonus Bank" balance and paid out in the
            manner provided below.

            4.1  Target Bonus.  The Target Bonus Awards will be
                 determined by the Committee according to a schedule
                 that associates job responsibilities with a specified
                 dollar amount of Target Bonus. If a Participant moves
                 from one global job level to another during a Plan Year
                 by virtue of a change in job responsibilities (except
                 for changes as a result of moves to certain global job
                 levels designated by the Committee or changes between
                 part-time and full-time status) his or her Target Bonus
                 will not be changed for the Plan Year in which the move
                 occurs.  The Target Bonus will be based on the currency
                 in which the highest portion of base pay is regularly
                 paid.  The Committee shall determine the appropriate
                 foreign exchange conversion methodology in its
                 discretion.

            4.2  Declared Bonus.  A Declared Bonus is the Target Bonus
                 times the Bonus Multiple.

            4.3  Bonus Multiple.  The Bonus Multiple is Actual EVA minus
                 Target EVA over the Leverage Factor, plus one.

            4.4  Bonus Bank.  All bonus payments are made from the Bonus
                 Bank.  Each Participant's beginning Bonus Bank balance
                 in his/her first year of participation is zero.  The
                 Bonus Bank is increased or decreased for any plan year
                 by the amount of Declared Bonus.  If the available
                 Bonus Bank balance is positive, the participant will be
                 paid from such balance up to the Target Bonus amount,
                 plus one third of any such balance that remains after
                 subtracting the Target Bonus from available Bonus Bank
                 balance. If the available Bonus Bank balance is
                 negative, no payment will occur.

            4.5  Target EVA.   The Target EVA for each year shall be
                 calculated as follows:

 Target EVA = [Prior Year's Actual EVA + Prior Year's Target EVA]+Expected
               -------------------------------------------------  Improvement
                                      2

            4.6  Expected Improvement.  The Expected Improvement is the
                 additional EVA amount determined by the Committee that
                 is used to assure that a minimum level of improvement
                 is achieved in order to earn target awards.

            4.7  Leverage Factor.  The Leverage Factor determines the
                 rate of change in bonuses as EVA surpasses or falls
                 short of Target EVA, determined by the Committee from
                 an evaluation of the long term volatility of industry
                 returns.

            4.8  Working Plan Example.  Examples of the mechanics of the
                 Plan are shown on Schedule A.



                                      ARTICLE V

                                 Plan Administration
                                 -------------------


            5.1  Time of Payment.  Payment from the Bonus Bank will be
                 made before March 1 of the year following the Plan
                 Year.

            5.2  Certification of Results.  Before any amount is paid
                 under the Plan, the Committee shall certify in writing
                 the calculation of EVA for the Plan Year and the
                 satisfaction of all other material terms of the
                 calculation of the Declared Bonus.

            5.3  New Hires, Promotions.  New hires or individuals
                 promoted who are first selected for participation by
                 the Committee effective on a date other than January 1
                 will participate on a pro-rata basis in their first
                 year of participation, based on the Declared Bonus
                 determined for the Plan Year, pro-rated for that period
                 of the year during which the Participant was selected
                 for participation in the Plan.

            5.4  Termination of Employment.  If a Participant ceases
                 employment with the Company before the end of a Plan
                 Year for reasons other than Retirement, Disability or
                 death, the Participant shall receive a fraction of a
                 Bonus for that Plan Year equal to the number of days
                 worked during the plan year divided by the total number
                 of days in the Plan Year, and his/her Bank Balance
                 shall be forfeited.  The Committee may make complete or
                 partial exceptions to this rule, with respect to the
                 Bank Balance only, in its sole discretion.

            5.5  Retirement, Disability or Death.  If a Participant
                 ceases employment with the Company because of
                 Retirement, Disability or death, the Participant or
                 personal representative, as the case may be, shall
                 receive full payment of his/her Bank Balance and a
                 bonus based on the Declared Bonus determined for the
                 Plan Year but pro-rated for that period of the year
                 during which the Participant was an active employee of
                 the Company.

            5.6  Plan Participation.  A Participant may not participate
                 in this Plan for any portion of a year for which he/she
                 is entitled to receive payment under the Eli Lilly and
                 Company Contingent Compensation Plan, and shall be
                 treated in accordance with 5.3.



                                     ARTICLE VI

                                 General Provisions
                                 ------------------


            6.1  Withholding of Taxes.  The Company shall have the right
                 to withhold the amount of taxes which in the sole
                 determination of the Company are required to be
                 withheld under law with respect to any amount due or
                 payable under the Plan.

            6.2  Expenses.  All expenses and costs in connection with
                 the adoption and administration of the plan shall be
                 borne by the Company.

            6.3  No Prior Right or Offer, No Right to Employment.
                 Except and until expressly granted pursuant to the
                 Plan, nothing in the Plan shall be deemed to give any
                 employee any contractual or other right to participate
                 in the benefits of the Plan.  No award to any such
                 Participant in any Plan Year shall be deemed to create
                 a right to receive any award or to participate in the
                 benefits of the Plan in any subsequent Plan Year.

            6.4  Rights Personal to Employee.  Any rights provided to an
                 employee under the Plan shall be personal to such
                 employee, shall not be transferable, except by will or
                 pursuant to the laws of descent or distribution, and
                 shall be exercisable during his/her lifetime, only by
                 such employee, or a court-appointed guardian for the
                 employee.

            6.5  Non-Allocation of Award.  In the event of a suspension
                 of the Plan in any Plan Year, as described in Section
                 11.1, no awards under the Plan for the Plan Year during
                 which such suspension occurs shall affect the
                 calculation of awards for any subsequent period in
                 which the Plan in continued.


                                     ARTICLE VII

                                     Limitations
                                     -----------


            7.1  No Continued Employment.  Neither the establishment of
                 the Plan nor the grant of an award thereunder shall be
                 deemed to constitute an express or implied contract of
                 employment of any Participant for any period of time or
                 in any way abridge the rights of the Company to
                 determine the terms and conditions of employment or to
                 terminate the employment of any employee with or
                 without notice or cause at any time.

            7.2  No Vested Rights.  Except as expressly provided herein,
                 no employee or other person shall have any claim of
                 right (legal, equitable, or otherwise) to any award,
                 allocation, or distribution or any right, title, or
                 vested interest in any amounts in his/her Bonus Bank
                 and no officer or employee of the Company or any other
                 person shall have any authority to make representations
                 or agreements to the contrary.  No interest conferred
                 herein to a Participant shall be assignable or subject
                 to claim by a Participant's creditors.

            7.3  Non-alienation.  Except as provided in Subsection 5.1,
                 no Participant or other person shall have any right or
                 power, by draft, assignment, or otherwise, to mortgage,
                 pledge or otherwise encumber in advance any payment
                 under the plan, and every attempted draft, assignment,
                 or other disposition thereof shall be absolutely void.



                                    ARTICLE VIII

                                 Committee Authority
                                 -------------------


            8.1  Authority to Interpret and Administer.  Except as
                 otherwise expressly provided herein, full power and
                 authority to interpret and administer this Plan shall
                 be vested in the Committee.  The Committee may from
                 time to time make such decisions and adopt such rules
                 and regulations for implementing the Plan as it deems
                 appropriate for any Participant under the Plan.  Except
                 as to Participants who are executive officers of the
                 Company, the Committee may delegate in writing to
                 officers or employees of the Company the power and
                 authority granted by this Section 8.1 to interpret and
                 administer this Plan.  Any decision taken by the
                 Committee, or officer or employee to whom authority has
                 been delegated, arising out of or in connection with
                 the construction, administration, interpretation and
                 effect of the Plan shall be final, conclusive and
                 binding upon all Participants and any person claiming
                 under or through Participants.

            8.2  Committee Discretion to Revise Rates and Amounts.  The
                 Committee may, in its sole discretion, revise the
                 various rates, amounts and percentages provided in the
                 Plan from time to time (including, without limitation,
                 with respect to each of the foregoing defined terms),
                 provided that the methods and assumptions used in
                 making such determinations shall be established and
                 applied by the Committee on the basis of reasonable,
                 objective criteria that are applied in a uniform manner
                 from Plan Year to Plan Year.

            8.3  Financial And Accounting Terms.  Except as otherwise
                 provided, financial and accounting terms, including
                 terms defined herein, shall be determined by the
                 Committee in accordance with generally accepted
                 accounting principles and as derived from the audited
                 consolidated financial statements of the Company,
                 prepared in the ordinary course of business.


                                     ARTICLE IX

                                       Notice
                                       ------


            9.1  Any notice to be given to the Company or Committee
                 pursuant to the provisions of the Plan shall be in
                 writing and directed to Secretary, Eli Lilly and
                 Company, Lilly Corporate Center, Indianapolis, IN
                 46285.


                                      ARTICLE X

                                   Effective Date
                                   --------------


            10.1 This Plan shall be effective as of January 1, 1995, as
                 amended and restated effective January 1, 1996.



                                     ARTICLE XI

                             Amendments and Termination
                             --------------------------


            11.1 This Plan may be amended, suspended or terminated at
                 any time at the discretion of the Board of Directors of
                 Eli Lilly and Company, and may, except for this Section
                 11.1, be amended at any time by the Committee.


                                     ARTICLE XII

                                   Applicable Law
                                   --------------


            12.1 This Plan shall be governed by and construed in
                 accordance with the provisions of the laws of the State
                 of Indiana.

                                   SCHEDULE A
                                   ----------
YEAR ONE

Target EVA = $150MM
Actual EVA = $200MM
Leverage Factor = $100MM

Declared Bonus
- --------------
Actual EVA - Target EVA = $50MM
Bonus Multiple = 1 + (Actual EVA - Target EVA)/Leverage Factor
           1.5 = 1 + 50/100

Target Bonus = $20,000
Declared Bonus = $30,000 (1.5 x $20,000)

Bonus Bank
- ----------
     Declared Bonus             $30,000
     Beginning Bank Balance     $ -0-
                                -------
     Available Bank Balance     $30,000
     Target Bonus Paid          $20,000*
                                -------
     Remaining Balance          $10,000
     Pay 1/3 Remaining Balance   $3,333*
     Ending Bank Balance         $6,667

*Total bonus paid = $20,000 + $150MM) / 2 + 0
                  = $175MM


YEAR TWO

Target EVA = $175MM
Actual EVA = $140MM
Leverage Factor = $100MM

Declared Bonus
- --------------
Actual EVA - Target EVA = ($35MM)
Bonus Multiple = 1 + (Actual EVA - Target EVA)/Leverage Factor
          0.65 = 1 + (35)/100

Target Bonus = $20,000
Declared Bonus = $13,000 (0.65 x $20,000)

Bonus Bank
- ----------
     Declared Bonus                $13,000
     Beginning Bank Balance         $6,667
                                   -------
     Available Bank Balance        $19,667
     Target Bonus Paid             $19,667*
        (up to available balance)
     Remaining Balance                  $0
     Pay 1/3 Remaining Balance          $0*
                                   -------
     Ending Bank Balance                $0

*Total bonus paid = $19,667 + $0 = $19,667

EVA Target Reset (for year three) = ($140MM + $175MM)/2 + 0
                                  = $157.5MM



               EXHIBIT 11.  COMPUTATION OF EARNINGS PER SHARE ON PRIMARY
                                AND FULLY DILUTED BASES

                       Eli Lilly and Company and Subsidiaries

                                               Year Ended December 31
                                             1995       1994       1993
                                             ----       ----       ----
                                             (Dollars in millions, except
                                              per-share data; shares in
                                              thousands)
   PRIMARY:
   Net income............................   $2,290.9   $1,286.1   $  480.2
   Average number of common shares
      outstanding........................    569,026    578,378    585,346   

   Add incremental shares:
      Stock plans and contingent payments      8,655      4,614      2,356
                                               -----     -------    ------

   Adjusted average shares...............    577,681    582,992    587,702
                                             =======    =======    =======
   Primary earnings per share............      $3.97   $   2.21     $   .82


   FULLY DILUTED:
   Net Income............................   $2,290.9   $1,286.1   $  480.2

   Average number of common shares
       outstanding.......................    569,026    578,378    585,346

   Add incremental shares:
       Stock plans and contingent payments    15,023      7,080      3,232
                                             -------    -------     ------

   Adjusted average shares                   584,049    585,458    588,578
                                             =======    =======    =======

   Fully diluted earnings per share......   $   3.92   $   2.20    $   .82




         EXHIBIT 12.  STATEMENT RE:  COMPUTATION OF RATIO OF
                      EARNINGS TO FIXED CHARGES


                                                 Years Ended December 31,
                                    ---------------------------------------

                                 1995     1994     1993      1992    1991
                                 ----     ----     ----      ----    ----

   Consolidated Pretax
   Income
     From Continuing
   Operations
     Before Changes in
     Accounting Principles    $1,765.6  $1,698.6  $ 662.8   $1,193.5  $1,626.3

   Interest from Continuing
     Operations                  324.6     129.2     96.1      108.4      87.1

   Less Interest Capitalized
     During the Period from
     Continuing Operations       (38.3)   (25.4)    (25.5)     (35.2)   (48.1)
                                  -----    -----     -----      -----    -----
   Earnings                   $2,051.9  $1,802.4  $ 733.4   $1,266.7 $1,665.3
                               =======   =======   ======    =======  =======

   Fixed Charges:

   Interest Expense from
     Continuing Operations     $324.6   $  129.2  $  96.1    $ 108.4   $ 87.1
                                =====    =======   ======     ======    =====
   Ratio of Earnings to
     Fixed Charges                6.3       14.0      7.6       11.7     19.1
                                =====    =======   ======     ======    =====


         EXHIBIT 13. ANNUAL REPORT TO SHAREHOLDERS FOR THE YEAR
                     ENDED DECEMBER 31, 1995


         REVIEW OF OPERATIONS


         STRATEGIC ACTIONS

         During 1995,  the company  completed the  divestiture of  the  nine
         Medical Devices  and Diagnostics  (MDD)  Division businesses.    In
         1994, a separate company, Guidant Corporation (Guidant), was formed
         to be the parent  company of five of  the MDD companies:   Advanced
         Cardiovascular Systems, Inc.; Cardiac Pacemakers, Inc.; Devices for
         Vascular Intervention, Inc.; Heart  Rhythm Technologies, Inc.;  and
         Origin  Medsystems,   Inc.     In  December   1994,  Guidant   sold
         approximately 20 percent of its common  stock in an initial  public
         offering.  In September 1995, the company distributed its remaining
         80 percent  interest in  Guidant through  a splitoff,  an  exchange
         offer under  which Lilly  shareholders could  exchange their  Lilly
         shares for Guidant shares.  Pursuant to the splitoff, approximately
         16.5 million shares of the company's  common stock (expressed on  a
         pre-stock-split basis) were exchanged for the Guidant shares  owned
         by the company, resulting in an increase in the company's  treasury
         stock and a  corresponding reduction  of shares  outstanding.   The
         splitoff resulted in a tax-free  gain calculated as the  difference
         between the market  and carrying values  of the  shares of  Guidant
         common stock held  by the  company on  the expiration  date of  the
         exchange offer.    Sales  of  three  of  the  MDD  companies,  IVAC
         Corporation, Pacific Biotech, Inc., and Physio-Control Corporation,
         were completed  during  1994  and  1995,  and  the  divestiture  of
         Hybritech Incorporated was finalized in January 1996.

         As a consequence of the divestiture,  the operating results of  the
         MDD companies have been  reflected as "discontinued operations"  in
         the company's  financial statements  and  have been  excluded  from
         consolidated sales and expenses reflected therein.  As a result  of
         completion of the divestiture, the company recognized a net gain of
         $921.5 million.   All  assets, liabilities  and equity  of the  MDD
         businesses have been removed from the company's balance sheet.  See
         Note 4  to  the consolidated  financial  statements for  a  further
         discussion.

         In December 1995, the company acquired Integrated Medical  Systems,
         Inc. (IMS), which develops  and operates physician-focused  medical
         communications  networks.     The  acquisition   will  provide   an
         opportunity to forge  closer ties with  the health care  community,
         deliver health care information quickly to users of the network and
         provide disease-management utilization tools for current and future
         subscribers of the system.   The company hopes  to utilize the  IMS
         networks  in  conjunction   with  the   pharmacy-benefit-management
         capabilities of PCS  Health Systems, Inc.  (PCS), in  an effort  to
         create a nationally  integrated information  technology system  for
         health care providers and payers.   See Note 2 to the  consolidated
         financial statements for a further discussion.

         STOCK SPLIT

         On October 16, 1995,  the company's board  of directors declared  a
         two-for-one stock split to be effected in the form of a 100 percent
         stock dividend payable to  shareholders of record  at the close  of
         business November 15, 1995.   The outstanding and  weighted-average
         number of shares  of common stock  and per-share  data herein  have
         been adjusted to reflect the stock split.  Treasury shares held  by
         the company were not split.

         OPERATING RESULTS OF CONTINUING OPERATIONS AND NET INCOME--1995

         Worldwide sales rose 18  percent in 1995,  to nearly $6.8  billion.
         The factor that contributed most to  the increase was a 17  percent
         rise in unit volume.   Prices decreased  1 percent, while  exchange
         rates increased sales by 2 percent.

         The company achieved sales increases both in the United States  and
         abroad.  Sales in the United States were $3.8 billion, a 16 percent
         increase.  Sales outside  the United States  were $3.0 billion,  an
         increase of 21 percent from the previous year.

         Pharmaceutical  sales  for  the  year  increased  approximately  19
         percent, to approximately $6.3  billion, led by the  antidepressant
         Prozac (up  24  percent, to  approximately  $2.1 billion).    Other
         products contributing  significantly  to  worldwide  pharmaceutical
         sales growth included the  antiulcer drug Axid  (up 13 percent,  to
         $548 million), the human insulin product Humulin (up 19 percent, to
         $794 million), the human growth  hormone Humatrope (up 19  percent,
         to $269 million) and the oral antibiotic Lorabid (up 31 percent, to
         $169 million).   Sales  also benefited  from the  inclusion of  PCS
         service revenue.  All  the company's therapeutic classes  reflected
         increased sales compared with 1994 levels.  Pharmaceutical sales in
         the United States increased 17 percent, to nearly $3.6 billion,  in
         1995 despite  continued growth  in  product discounts  and  rebates
         associated with the company's  increased participation in  managed-
         care programs.  The negative effects of federally mandated  rebates
         to the states on sales to Medicaid recipients declined in 1995,  to
         $143.1 million, a 14 percent decrease  from 1994.  This decline  is
         primarily the result  of changes  in the  mix of  products sold  to
         Medicaid recipients.  The company anticipates product discounts and
         rebates associated  with  managed  care and  Medicaid  programs  to
         increase in 1996.  Pharmaceutical sales outside the U.S.  increased
         22 percent, to  nearly $2.7 billion,  in 1995.   The  international
         sales growth relates  largely to volume  growth resulting from  the
         company's continued  globalization efforts  and favorable  exchange
         rates.

         U.S. sales  of  the oral  antibiotic  cefaclor, which  were  $227.5
         million in 1995 (approximately 3 percent of the company's worldwide
         sales), declined by 42  percent compared with  1994.  This  decline
         was offset in  part by sales  of cefaclor outside  the U.S.,  which
         increased 18  percent, to  $494.7 million.    The decline  in  U.S.
         cefaclor sales is  primarily due  to pricing  pressures and  strong
         generic competition.  Since May  1995, several companies have  been
         marketing generic forms of cefaclor capsules in the United  States.

         Quantities of  the  competing generic  product  to date  have  been
         greater than anticipated by the company.  The company expects  that
         generic cefaclor competition, together with strong competition from
         other anti-infectives, will result in  a continued decline in  U.S.
         cefaclor sales in 1996.   Although the  impact of this  competition
         cannot be predicted with  certainty, it is not  expected to have  a
         material adverse effect on the company's 1996 consolidated  results
         of operations.

         Worldwide sales  of  Elanco  Animal Health  products  increased  11
         percent, to  $512.4 million.   Sales  increased  6 percent  in  the
         United States and 14 percent outside  the U.S. compared with  1994.
         The worldwide  sales increase  occurred across  the entire  product
         line but was led primarily by  TylanR, an antibiotic for swine  and
         cattle.

         Cost of sales was 27.9 percent for 1995 compared with 29.4  percent
         in 1994.  This decrease  is primarily attributable to  productivity
         improvements, increased production to  meet larger product  demands
         and favorable  exchange rates  that were  partially offset  by  the
         inclusion of PCS.

         Research and  development expenses  increased 24  percent in  1995.
         Research expenditures  continue to  increase primarily  due to  the
         growth of global clinical trials to support the company's extensive
         pipeline  of  potential  new  products,  including  olanzapine  and
         raloxifene.  The company anticipates that research and  development
         expenses will grow at a  rate in excess of  sales for at least  the
         next year as  raloxifene moves into  the final  stages of  clinical
         research.

         Marketing and administrative expenses increased 33 percent in 1995.
         Marketing costs increased largely due  to the continued efforts  to
         expand the company's  products globally,  particularly in  emerging
         markets.    Administrative  expenses  increased  primarily  due  to
         charges for anticipated settlements of certain pending  litigation,
         the inclusion of  PCS, increased compensation  accruals due to  the
         company's  performance-based  bonus  programs  and  development  of
         enhanced information technology capabilities.

         The company  implemented  various  restructuring  and  streamlining
         initiatives and strategic  actions in both  1993 and  1992.   These
         strategic actions were  taken largely in  response to the  changing
         business  environment  in  which  the  company  operates  and  were
         designed to  enhance the  company's core  competencies, enable  the
         company  to  deliver  more  clinical  and  economic  value  to  its
         customers worldwide, streamline global manufacturing operations and
         improve  the  company's  competitiveness.    See  Note  3  to   the
         consolidated financial statements for a further discussion.  Of the
         1993 and 1992 restructuring charges, approximately $51 million  and
         $110 million  was paid  in cash  in  1995 and  1994,  respectively.
         Charges yet to be paid in cash total approximately $253 million and
         are expected to be funded from  operations primarily over the  next
         few years.

         Interest expense  increased  in 1995,  to  $286.3 million,  due  to
         increased debt levels  associated with the  purchase of  PCS.   Net
         other income of $70.1 million for 1995 was $61.8 million lower than
         in 1994 due primarily  to the amortization  of goodwill related  to
         the PCS acquisition  of approximately $100  million.  The  goodwill
         amortization was partially offset  by nonrecurring income from  the
         sale of the U.S.  marketing rights to  certain products and  income
         received under a development contract.

         The effective tax rate for 1995  was 26 percent compared with  30.2
         percent in 1994.  The  1995 tax rate had  been forecasted to be  29
         percent; however,  after  confirmation  in the  fourth  quarter  of
         evolving long-term  operating and  tax  trends outside  the  United
         States, confidence  in  the  sustainability of  a  lower  level  of
         taxation resulted  in an  effective tax  rate for  the year  of  26
         percent.  The decline is primarily the result of changes in the mix
         of earnings between jurisdictions  having lower tax rates  compared
         with those having  higher rates  and the  effectiveness of  various
         tax-planning strategies.  The  full-year  impact of  the  tax  rate
         reduction was  recognized in  the fourth  quarter, resulting  in  a
         benefit of $42.1 million  in fourth-quarter income from  continuing
         operations and  net  income.    The  company  expects  current  tax
         strategies will  allow  its  1996  effective  tax  rate  to  remain
         approximately the same as the 1995 rate.

         For 1995, increased sales-related  gross margins and the  favorable
         impact of the reduced estimated tax  rate were partially offset  by
         the growth in operating expenses, including  PCS and the impact  of
         PCS-acquisition-related  expenses,  resulting   in  a  10   percent
         increase in  income from  continuing operations  and a  12  percent
         increase in earnings per share from continuing operations, to  $1.3
         billion and  $2.30, respectively.   The  percentage increase  would
         have been  lower if  not for  the special  charges of  $66  million
         incurred in 1994 relating  to a voluntary  antibiotic recall and  a
         charge of $58.4 million for  acquired research associated with  the
         acquisition of Sphinx Pharmaceuticals Corporation.

         Net income and earnings per share increased $1.0 billion and $1.81,
         respectively,  in  1995  compared  with  1994.    Net  income   was
         significantly affected by  the net gain of $921.5 million  realized
         from the  company's divestiture  of its  MDD businesses,  primarily
         Guidant.

         For the fourth quarter, in addition to the previously noted benefit
         from the  reduced  effective  tax rate,  earnings  per  share  from
         continuing operations of   $.57 and  net income per  share of  $.63
         were favorably affected by the reduced number of shares outstanding
         as a  consequence of  the  Guidant splitoff.    The impact  of  the
         reduced shares outstanding was $.03 and $.04 on earnings per  share
         from continuing  operations  and  net income,  respectively.    The
         impact of the reduced  number of shares  outstanding on the  annual
         per-share amounts was not material.

         In the United States, significant health-care-reform legislation at
         the federal  level  does  not  appear  likely  in  the  near  term.
         However, various reform measures are  currently being debated in  a
         number of states.   Outside the  United States,  changes in  health
         care  delivery  and   pharmaceutical  reimbursement  policies   are
         occurring to  varying degrees.   It  is  difficult to  predict  the
         impact these changes will have on the industry or the company.   As
         previously noted, the  company continues to  position itself to  be
         responsive to these changes.


         OPERATING RESULTS OF CONTINUING OPERATIONS AND NET INCOME -- 1994

         Worldwide sales rose  10 percent  in 1994,  to $5.7  billion.   The
         factor that contributed most to the increase was an 11 percent rise
         in unit volume.  Price  declines reduced sales by 2 percent,  while
         exchange rates increased sales by 1  percent.  Sales in the  United
         States were $3.3 billion, a 6 percent increase.  Sales outside  the
         United States were  $2.4 billion, an  increase of  16 percent  from
         1993.

         Pharmaceutical sales for 1994  increased approximately 10  percent,
         to $5.2 billion, led by Prozac  (up 39 percent, to  approximately
         $1.7  billion).    Other  products  contributing  significantly  to
         worldwide  pharmaceutical  sales  growth  included  Axid,  Humulin,
         Humatrope and  Lorabid.   Sales also  benefited slightly  from  the
         inclusion of PCS.   Sales of central-nervous-system,  diabetes-care
         and gastrointestinal  products, as  therapeutic classes,  increased
         from 1993 levels.  However,  sales of anti-infectives decreased  as
         international sales growth was offset by a decline in the U.S.   In
         addition, U.S. sales of DobutrexR declined approximately 91 percent
         compared with 1993 as a result  of the product's patent  expiration
         in October 1993.  U.S. pharmaceutical sales increased 6 percent, to
         nearly  $3.1  billion,  in  1994  despite  the  growth  in  product
         discounts and  rebates  associated  with  the  company's  increased
         participation in managed-care programs and the negative effects  of
         federally mandated  rebates  to the  states  on sales  to  Medicaid
         recipients.  For 1994, Medicaid rebates  totaled $166 million, a  6
         percent increase over 1993.  Pharmaceutical sales outside the  U.S.
         increased  17   percent,  to   nearly   $2.2  billion,   in   1994.
         Contributing substantially to the  international sales growth  were
         strong results in emerging markets, including Eastern Europe,  Asia
         and Latin America.

         Sales of the  oral antibiotic Ceclor  in the  United States,  which
         accounted for approximately  7 percent of  the company's  worldwide
         sales in 1994, declined in both 1993 and 1994 primarily as a result
         of intense competition from other anti-infective products.

         Worldwide sales  of  Elanco  Animal  Health  products  increased  6
         percent, to $464 million.  Sales increased 1 percent in the  United
         States and 9  percent outside  the U.S.  compared with  1993.   The
         worldwide sales increase was led by Tylan, an antibiotic for  swine
         and cattle.

         Manufacturing costs of  products sold  increased in  1994, to  29.4
         percent of sales, from 27.9 percent of sales in 1993.  The increase
         is due primarily to a decision in early 1994 to reduce certain  in-
         process inventory  levels, which  resulted  in greater  amounts  of
         overhead costs being  charged against  income.   This increase  was
         partially offset by a favorable product mix and continued reduction
         in spending.

         Research and  development expenses  increased 11  percent in  1994,
         largely due to the growth of global clinical trials to support  the
         company's extensive pipeline of potential new products.  See Note 2
         to the  consolidated  financial  statements  for  a  discussion  of
         acquired research.

         Marketing and administrative expenses increased 5 percent in  1994.
         Marketing costs increased largely due to the continued expansion of
         sales forces  in emerging  international markets.    Administrative
         expenses reflected a decrease compared with 1993 due in part to the
         impact of special charges taken as part of the 1993  restructuring.
         This decrease  was  offset  in part  by  increased  legal  expenses
         associated with litigation resolved during the year.

         In the first  half of  1994, the  company incurred  $66 million  of
         pretax charges associated  with the  March 31  voluntary recall  of
         three of the  company's liquid oral  antibiotics.   The recall  was
         made after four instances were reported of small plastic caps being
         found in the antibiotics.  Shipments of these products were resumed
         during the second and third quarters.

         Interest expense for 1994 reflected an increase compared with  1993
         of approximately  $33  million,  or  47  percent.    The  increased
         interest expense  was  the  result of  higher  debt  levels,  as  a
         consequence of the PCS acquisition  and borrowings made by  Guidant
         as part of the  company's divestiture strategy.   Net other  income
         for 1994 increased $29 million, or  28 percent, compared with  1993
         primarily due  to  increased  interest and  joint  venture  income,
         offset in part by the amortization of goodwill from the acquisition
         of PCS.

         The effective tax rate for 1994 was 30.2 percent compared with 29.9
         percent in 1993.   This increase was due  largely to the impact  of
         the Omnibus Budget Reconciliation Act (OBRA) of 1993, which reduced
         the tax benefit from operations in Puerto Rico.

         Net income  and earnings  per share  were $1.3  billion and  $2.22,
         respectively,  for  1994.     These  amounts  reflect   substantial
         increases over  1993  due  to both  the  negative  impact  on  1993
         operations of the company's 1993 restructuring and special  charges
         and the continued growth of the company's pharmaceutical and animal
         health businesses in 1994.  This growth was partially offset by the
         impact of increased  interest expense related  to the Guidant  debt
         and the debt used to finance  the PCS acquisition, amortization  of
         goodwill associated with  the PCS acquisition,  the product  recall
         and the acquired research related to the Sphinx acquisition.


         FINANCIAL CONDITION

         The company maintained  a sound financial  position in  1995.   The
         cash generated  from  operations  provided the  resources  to  fund
         capital expenditures, dividends and debt  service.  As of  December
         31, 1995, cash, cash equivalents and short-term investments totaled
         $1.1 billion compared  with $746.7  million at  December 31,  1994.
         Total debt at December  31, 1995, was $4.5  billion, a decrease  of
         $348.5 million  from the  prior  year.   The  decrease in  debt  is
         primarily  due  to  the  splitoff  of  Guidant.    Short-term  debt
         aggregating $1.9 billion  is primarily  in the  form of  commercial
         paper.  The  company believes that  cash generated from  operations
         will be sufficient to fund essentially all the company's  operating
         needs, including debt service,  capital expenditures and  dividends
         in 1996.

         In 1994,  the  company  incurred additional  debt  to  finance  the
         acquisition of PCS and as part  of the overall Guidant  divestiture
         strategy.  As a consequence of  the additional debt and  heightened
         competition for the antibiotic Ceclor, the company's long-term debt
         rating was lowered from AAA to  AA by Standard & Poor's in  October
         1994 and from Aa1 to Aa3  by Moody's in November 1994.   Commercial
         paper ratings of A1+  by Standard & Poor's  and Prime-1 by  Moody's
         were affirmed.  These ratings were reaffirmed in 1995.  Maintenance
         of these ratings  in the future  will depend  largely on  continued
         strong  financial  performance  and  reductions  of  existing  debt
         levels.

         Since the date  of the PCS  acquisition, the  company has  replaced
         $1.8  billion  of  the  commercial   paper  used  to  finance   the
         acquisition with fixed-rate debt with maturities ranging from 5  to
         40 years, including  the January 1996  issuance of 20  and 40  year
         fixed-rate notes  aggregating $500  million.   See  Note 7  to  the
         consolidated financial statements for additional information.

         The  company  believes  that  amounts  available  through  existing
         commercial paper programs should be adequate to fund maturities  of
         short-term borrowings.   The outstanding commercial  paper is  also
         backed up by $3.0 billion of committed bank credit facilities.

         The company  conducts its  business in  various foreign  currencies
         and, as  a result,  is subject  to the  exposures that  arise  from
         foreign exchange rate movements.  The company's hedging activities,
         all of which are for "purposes  other than trading" (as defined  by
         Statement of Financial Accounting Standards No. 119), are initiated
         within  the  guidelines  of  documented  corporate  risk-management
         policies and do not create additional risk because gains and losses
         on these  instruments  generally offset  losses  and gains  on  the
         assets, liabilities and transactions being hedged.

         The company uses foreign currency forward contracts, currency swaps
         and option contracts  to reduce the  effect of fluctuating  foreign
         currencies.   Instruments related  to transactional  exposures  are
         carried in the  financial statements  at current  rates, with  rate
         changes  reflected  directly  in  income.    Gains  and  losses  on
         instruments  designed   to  hedge   anticipated  foreign   currency
         transactions are deferred and recognized in the same period as  the
         hedged transactions.   Further, interest rate  swap agreements  are
         used to reduce the impact of  interest rate changes on net  income.
         In 1995, the impact of the company's risk-management strategies was
         not material to the results of operations.

         Capital expenditures  of  $551.3  million during  1995  were  $25.2
         million less  than  in  1994, as  new  manufacturing,  development,
         research  and   administrative   facilities   construction   neared
         completion.  The company expects near-term capital expenditures  to
         decline slightly from 1995 levels.  Sufficient cash flows exist  to
         meet these near-term requirements.

         The company  is  a  40  percent  partner  in  DowElanco,  a  global
         agricultural products joint venture, with The Dow Chemical Company.
         The company  holds a  put option,  which became  exercisable  after
         October 31,  1994, which  requires Dow  to purchase  the  company's
         interest in DowElanco  at specified amounts  based largely on  fair
         market value.  The company did not exercise its put option in 1995.

         Common stock held in treasury increased to $1.6 billion at December
         31, 1995.  The increase was largely due to the distribution of  the
         company's remaining  80 percent  interest  in Guidant  through  the
         splitoff.  Pursuant to  the splitoff, 16,504,298 shares  (expressed
         on a  pre-stock-split basis)  of the  company's common  stock  were
         exchanged for  Guidant shares,  resulting in  the increase  in  the
         company's treasury  stock  and  corresponding  decrease  in  shares
         outstanding.

         Dividends of $1.31  per share  were paid  in 1995,  an increase  of
         approximately 5 percent from the $1.25 per share paid in 1994.   In
         the fourth quarter, the quarterly  dividend was increased $.02  per
         share (6 percent).  This increase,  the second in 1995, was  nearly
         twice the previous dividend increase.  The 1994 dividend  reflected
         a 3 percent increase from  the $1.21 per share  paid in 1993.   The
         year 1995  was the  111th consecutive  year that  the company  made
         dividend payments and the 28th consecutive year in which  dividends
         have been increased.


         ENVIRONMENTAL AND LEGAL MATTERS

         As with other industrial enterprises, the company's operations  are
         subject  to  complex  and   changing  federal,  state,  and   local
         environmental laws and regulations, which will continue to  require
         capital investment and operational expenses.  The company also  has
         been  designated  a   potentially  responsible   party  under   the
         Comprehensive Environmental Response,  Compensation, and  Liability
         Act, commonly known as Superfund, with respect to approximately  10
         sites with which  the company had  varying degrees of  involvement.
         Further, the company  continues remediation of  certain of its  own
         properties consistent with  current environmental  practices.   The
         company has accrued for  estimated Superfund costs and  remediation
         of  its  own  properties,  taking  into  account,  as   applicable,
         available information regarding site conditions, potential  cleanup
         methods, estimated costs and the extent to which other parties  can
         be expected to contribute to those costs.  In addition, the company
         has accrued for certain other environmental matters.

         During 1995, the company  continued to be named  as a defendant  in
         lawsuits involving Prozac.  However, the number of new case filings
         in 1995 and the number of pending cases declined significantly from
         1994 levels.

         The company  has  been named,  together  with numerous  other  U.S.
         prescription drug manufacturers, as a  defendant in a large  number
         of related actions in federal courts and the courts of four  states
         brought by  retail pharmacies  alleging violations  of federal  and
         state antitrust  and pricing  laws.   The federal  suits include  a
         class action on behalf of the  majority of U.S. retail  pharmacies.

         The class  plaintiffs  allege  an industrywide  agreement  to  deny
         favorable prices on  prescription drugs to  retail pharmacies  that
         manufacturers grant to managed-care organizations and certain other
         purchasers.   Other  related  suits, brought  by  several  thousand
         pharmacies,  involve  claims  of  price  discrimination  under  the
         federal Robinson-Patman Act  or other pricing  laws.  In  addition,
         claims have been  brought on  behalf of  consumers of  prescription
         drugs in eight states.  The company and 11 other manufacturers have
         agreed to settle  the federal class  action case.   The  settlement
         amount, which is not material, was accrued in the fourth quarter of
         1995.  The settlement is subject to approval of the district court.
         In the federal Robinson-Patman Act cases, the court in the Northern
         District  of  Illinois  has   designated  certain  plaintiffs   and
         defendants named  in  the individual  suits  to participate  in  an
         initial trial  or trials  of  the plaintiffs'  Robinson-Patman  Act
         claims.   Robinson-Patman claims  asserted in  suits filed  against
         nondesignated defendants, including the company, are stayed.

         While it is not possible to predict or determine the outcome of the
         product liability, antitrust or other legal actions brought against
         the company  or the  ultimate cost  of environmental  matters,  the
         company believes the  costs associated with  all such matters  will
         not have a  material adverse effect  on its consolidated  financial
         position or  liquidity  but  could  possibly  be  material  to  the
         consolidated results of  operations in any  one accounting  period.
         For additional information on litigation and environmental matters,
         see Note 12 to the consolidated financial statements.


         1995 Financial Highlights
         ELI LILLY AND COMPANY AND SUBSIDIARIES
         (Dollars in millions, except per-share data)



                                 December 31    1995       1994     Change
         -----------------------------------------------------------------

         Net sales..........................  $6,763.8   $5,711.6     18%

         Research and development expenses..   1,042.3      838.7     24%

         Income from continuing operations..   1,306.6    1,185.1     10%

         Net income.........................   2,290.9    1,286.1     78%

         Earnings per share:
           Income from continuing operations      $2.30      $2.05    12%
           Net income.......................       4.03       2.22    82%

         Dividends paid per share...........       1.31       1.25     5%

         Capital expenditures...............    $551.3     $576.5    (4)%

         Return on shareholders' equity.....      42.5%      25.9%

         Return on assets...................      15.6       11.8
         Income from continuing operations
         as a percent of sales..............      19.3       20.7



         Results of  operations of  the  Medical Devices  and  Diagnostics
         (MDD) Division  have been reflected as "discontinued  operations"
         and are  excluded  from  consolidated  net  sales  and  operating
         expenses.   Net  income for  1995  includes  a net  gain  on  the
         divestiture of  MDD.   Amounts for  1994  reflect the  impact  of
         acquired research and special charges.   See Notes 2, 3 and 4  to
         the consolidated financial statements.

         Per-share data  for  both years  reflect  the two-for-one  stock
         split in  1995.    See  Note  9 to  the  consolidated  financial
         statements.






         Consolidated Statements of Income
         ELI LILLY AND COMPANY AND SUBSIDIARIES
         (Dollars in millions, except per-share data)



                 Year Ended December 31        1995      1994      1993
         -------------------------------------------------------------------

         Net sales......................     $6,763.8  $5,711.6  $5,198.5

         Cost of sales..................      1,885.7   1,679.7   1,448.0
         Research and development.......      1,042.3     838.7     755.0
         Acquired research (Note 2).....         -         58.4      -
         Marketing and administrative...      1,854.0   1,398.3   1,332.4
         Restructuring and special charges
            (Note 3)....................         -         66.0   1,032.6
         Interest expense...............        286.3     103.8      70.6
         Other income--net..............        (70.1)   (131.9)   (102.9)
                                               -------    ------    ------
                                              4,998.2   4,013.0   4,535.7
                                              -------   -------   -------

         Income from continuing operations
         before income taxes and cumulative
         effect of change in accounting 
         principle......................      1,765.6   1,698.6     662.8

         Income taxes (Note 10).........        459.0     513.5     198.0
                                              -------    -------   -------

         Income from continuing operations
         before cumulative effect of change in
         accounting principle...........      1,306.6   1,185.1     464.8

         Discontinued operations, net of tax
          (Note 4)......................        984.3     101.0      26.3
                                              -------    -------  -------

         Income before cumulative effect of
         change in accounting principle...    2,290.9   1,286.1     491.1

         Cumulative effect of change in
         accounting principle - net of tax
          (Note 5)........................        -         -       (10.9)
                                              -------    ------     ------

         Net income.......................   $2,290.9  $1,286.1    $480.2
                                              =======   =======     =====

         Earnings per share:

          Income from continuing operations
             before cumulative effect of
             change in accounting principle      $2.30     $2.05     $ .79
          Discontinued operations........         1.73       .17       .05
          Cumulative effect of change in
             accounting principle........          -          -       (.02)
                                                  ----      ----       ----

          Net income.....................        $4.03     $2.22     $ .82
                                                  ====      ====      ====

         See notes to consolidated financial statements.



         Consolidated Balance Sheets
         ELI LILLY AND COMPANY AND SUBSIDIARIES
         (Dollars in millions)


                                December 31           1995       1994
         -------------------------------------------------------------
         Assets

         Current Assets
         Cash and cash equivalents..........       $  999.5   $  536.9
         Short-term investments.............           84.6      209.8
         Accounts receivable, net of allowances of
           $55.1 (1995) and $46.6 (1994)....        1,520.5    1,550.2
         Other receivables..................          287.9      284.4
         Inventories (Note 1)...............          839.6      968.9
         Deferred income taxes (Note 10)....          259.2      245.0
         Prepaid expenses...................          147.3      167.1
                                                    -------     ------
            Total current assets............        4,138.6    3,962.3


         Other Assets
         Prepaid retirement (Note 11).......          484.2      411.9
         Investments (Note 6)...............          573.8      464.1
         Goodwill and other intangibles, net of
           allowances for amortization of $192.2
           (1995) and $326.2 (1994) (Note 2)        4,105.2    4,411.5
         Sundry...................................    871.4      846.1
                                                    -------    -------
                                                    6,034.6    6,133.6



         Property and Equipment (Note 1)            4,239.3   4,411.5
                                                    -------   -------


                                                  $14,412.5  $14,507.4
                                                   ========   ========






         Consolidated Balance Sheets
         ELI LILLY AND COMPANY AND SUBSIDIARIES
         (Dollars in millions)


                                      December 31      1995      1994
         ----------------------------------------------------------------
         Liabilities and Shareholders' Equity

         Current Liabilities
         Short-term borrowings (Note 7)               $1,908.8  $2,724.4
         Accounts payable                              1,018.0     878.2
         Employee compensation                           316.0     304.6
         Dividends payable                               189.1     188.8
         Income taxes payable (Note 10)                  660.5     508.4
         Other liabilities                               874.6   1,065.1
                                                       -------   -------
            Total current liabilities                  4,967.0   5,669.5

         Other Liabilities
         Long-term debt (Note 7)                       2,592.9   2,125.8
         Deferred income taxes (Note 10)                 295.5     188.9
         Retiree medical benefit obligation
            (Note 11)                                    147.8     170.5
         Other noncurrent liabilities                    976.7     997.1
                                                       -------   -------
                                                       4,012.9   3,482.3

         Commitments and contingencies (Note 12)           -         -

         Shareholders' Equity (Notes 8 and 9)

         Common stock--no par value
            Authorized shares: 800,000,000
            Issued shares:     568,902,054               355.6     183.0
         Additional paid-in capital                      418.3     421.7
         Retained earnings                             6,484.3   5,062.1
         Deferred costs--ESOP                           (199.5)   (218.2)
         Currency translation adjustments                 (0.6)    (38.0)
                                                       -------   -------
                                                       7,058.1   5,410.6

         Less cost of common stock in treasury:
              1995 --  18,149,494 shares
              1994 --     871,514 shares               1,625.5      55.0
                                                      --------   -------
                                                       5,432.6   5,355.6
                                                      --------   -------
                                                     $14,412.5 $14,507.4
                                                      ========  ========

         See notes to consolidated financial statements.




         Consolidated Statements of Cash Flows
         ELI LILLY AND COMPANY AND SUBSIDIARIES
         (Dollars in millions)
                           Year Ended December 31   1995     1994      1993
         --------------------------------------------------------------------
         Cash Flows From Operating Activities

         Net income                               $2,290.9 $1,286.1  $  480.2

         Adjustments To Reconcile Net Income to
           Cash Flows From Operating Activities
              Net gain on disposition of
                discontinued operations             (921.5)      -        -
              Depreciation and amortization          553.7     432.2    398.3
              Change in deferred taxes               144.0     172.2   (231.6)
              Restructuring and special charges-
                -net of payments                       -         -    1,041.3
              Cumulative effect of change in
                 accounting principle                  -         -       10.9
              Other noncash expense (income)--net     (9.8)     63.1    (53.1)
                                                   -------   -------  -------
                                                   2,057.3   1,953.6  1,646.0

         Changes in operating assets and liabilities:
              Receivables--increase                 (189.3)   (322.9)   (32.1)
              Inventories--(increase) decrease       (22.1)    107.1   (192.3)
              Other assets--increase                (114.5)   (130.6)  (104.5)
              Accounts payable and other
                 liabilities--increase (decrease)     93.2     (74.9)   199.8
                                                   -------   -------  -------
                                                    (232.7)   (421.3)  (129.1)

         Net Cash From Operating Activities        1,824.6   1,532.3  1,516.9

         Cash Flows From Investing Activities
         Acquisitions                                (36.8) (4,050.8)   (56.1)
         Additions to property and equipment        (551.3)   (576.5)  (633.5)
         Disposals of property and equipment          21.5      58.7      5.4
         Additions to other assets                   (54.1)    (72.9)   (70.1)
         Reductions of investments                   430.8   1,387.0    889.3
         Additions to investments                   (372.9) (1,150.5)(1,001.7)
                                                    ------   -------   ------
         Net Cash Used for Investing Activities     (562.8) (4,405.0)  (866.7)

         Cash Flows From Financing Activities
         Dividends paid                             (747.2)   (723.1)  (708.4)
         Proceeds from Guidant initial public  
            offering                                  -        192.5     -
         Purchase of common stock and other
            capital transactions                    (156.0)   (111.0)   (25.8)
         Issuance under stock plans                   54.7      50.5     19.8
         Increase (decrease) in short-term 
            borrowings                              (967.7)  2,126.1   (152.7)
         Additions to long-term debt               1,019.5   1,478.1    383.8
         Reductions of long-term debt                (17.0)   (175.8)   (39.8)
                                                   -------   -------  -------
         Net Cash From (Used for) Financing 
            Activities                              (813.7)  2,837.3   (523.1)

         Effect of exchange rate changes on cash      14.5      32.7    (19.9)
                                                    -------   -------  -------
         Net increase (decrease) in cash and
            cash equivalents                         462.6      (2.7)   107.2
         Cash and cash equivalents at beginning
            of year                                  536.9     539.6    432.4
                                                   -------   -------  -------
         Cash and cash equivalents at end of year $  999.5  $  536.9  $ 539.6
                                                   -------   -------   -------

         See notes to consolidated financial statements.



         Segment Information

         Industry Data (Dollars in millions)     1995      1994      1993
         -----------------------------------------------------------------
         Net sales--to unaffiliated customers
           Life-sciences products and services
             Central nervous system             $2,266.4  $1,835.6  $1,393.6
             Anti-infectives                     1,673.9   1,634.4   1,731.4
             Endocrine                           1,179.1   1,006.1     885.3
             Gastrointestinal                      548.4     487.4     396.8
             Animal health                         512.4     463.6     439.1
             Health care management                259.4      25.1        -
             All other                             324.2     259.4     352.3
                                                 -------   -------    ------
         Net sales                              $6,763.8  $5,711.6  $5,198.5
                                                 =======   =======   =======

         Life-sciences products  and  services  include a  broad  range  of
         pharmaceuticals  used  for  the  treatment  of  human  and  animal
         diseases and the company's health-care-management activities.  The
         largest category of the products is central-nervous-system agents,
         which  include  Prozac,  DarvonR  and  PermaxR.    Anti-infectives
         include Ceclor, Keflex, KefzolR, Lorabid, Nebcin R, TazidimeR and
         Vancocin.   Endocrine  products  consist primarily  of  Humatrope,
         Humulin and IletinR.  Other major groups are gastrointestinal, all
         of which is Axid, and  animal health products that  include Tylan,
         an antibiotic for  promoting feed efficiency  and growth in  swine
         and  cattle;  RumensinR,  a  nonhormonal  cattle  feed  additive;
         MicotilR,  an   antibiotic   for   bovine   respiratory   disease;
         anticoccidial agents for use  in broilers and layer  replacements,
         the largest of which is  CobanR; and other products  for livestock
         and poultry.      Health  care  management includes  revenue  from
         pharmacy benefit management,  such as  pharmacy claims  processing
         and   adjudication   as   well   as    physician-focused   medical
         communications networks, of  which PCS  is the largest  component.
         Major products in  the all-other  category include  cardiovascular
         therapy products,  of which  Dobutrex is  the  largest, and  other
         miscellaneous pharmaceutical products.

         Most  of  the  pharmaceutical  products  are  distributed  through
         wholesalers  that  serve  physicians,  dentists,   pharmacies  and
         hospitals.  In  1995, the  company's largest wholesaler  accounted
         for approximately 11  percent of consolidated  net sales.   Animal
         health products  are sold  to wholesale  distributors,  retailers,
         manufacturers and producers.

     Geographic Information (Dollars in millions)   1995     1994     1993
     ----------------------------------------------------------------------

     Net sales
       United States
          Sales to unaffiliated customers        $3,812.9  $3,281.5  $3,101.5
          Transfers to other geographic areas       485.5     405.2     394.6
                                                  -------   -------   -------
                                                  4,298.4   3,686.7   3,496.1
       Europe, Middle East and Japan
          Sales to unaffiliated customers         2,193.8   1,765.3   1,526.4
          Transfers to other geographic areas       336.9     269.0     218.5
                                                  -------    ------   -------
                                                  2,530.7   2,034.3   1,744.9
       Other
          Sales to unaffiliated customers           757.1     664.8     570.6
          Transfers to other geographic areas        13.8      11.3       3.9
                                                    -----     -----     -----
                                                    770.9     676.1     574.5
       Eliminations--transfers between
         geographic areas                          (836.2)   (685.5)   (617.0)
                                                   ------     ------   ------
                                                 $6,763.8  $5,711.6  $5,198.5
                                                  =======   =======   =======

     Income from continuing operations before
       income taxes and cumulative effect of
       change in accounting principle
          United States                          $  997.8  $1,067.0   $444.3
          Europe, Middle East and Japan             697.1     554.2    158.0
          Other                                      92.1     102.9     74.1
          Eliminations and adjustments              (21.4)    (25.5)   (13.6)
                                                    -----     -----    -----
                                                 $1,765.6  $1,698.6   $662.8
                                                  =======   =======    =====

     Total assets
       United States                            $11,321.8 $12,105.0 $7,187.8
       Europe, Middle East and Japan              3,178.0   3,209.1  2,507.1
       Other                                        527.0     505.3    382.5
       Eliminations and adjustments                (614.3) (1,312.0)  (453.8)
                                                   ------   -------    ------
                                                $14,412.5 $14,507.4 $9,623.6
                                                 ========  ========  =======

         Transfers between  geographic  areas are  made  at prices  that  are
         intended to  reasonably  approximate  an arms-length  value  of  the
         products.  Remittances to the United  States are subject to  various
         regulations of the respective governments as well as to fluctuations
         in exchange rates.




         Selected Quarterly Data (unaudited)
         ELI LILLY AND COMPANY AND SUBSIDIARIES
         (Dollars in millions, except per-share data)


         1995(1)                     Fourth(2)   Third     Second    First
         -------------------------------------------------------------------
         Net sales                    $1,799.8  $1,631.9  $1,614.8   $1,717.3
         Cost of sales                   494.1     419.7     459.4      512.5
         Operating expenses              850.9     704.7     696.8      643.9
         Other loss - net                (91.0)    (70.2)    (22.0)     (33.0)
         Income from:
            Continuing operations        311.3     310.5     310.0      374.8
            Discontinued operations       31.3     917.5      17.1       18.4
         Net income                      342.6   1,228.0     327.1      393.2

         Earnings per share:
            Continuing operations           .57       .54       .54        .65
            Discontinued operations         .06      1.60       .03        .03
            Net income                      .63      2.14       .57        .68
         Dividends paid per share           .3425     .3225     .3225      .3225
         Common stock prices:
            High                          57.00     47.19     39.69      38.44
            Low                           44.31     37.56     34.63      31.25

         1994(1)                       Fourth    Third    Second(3)   First(3)
         ---------------------------------------------------------------------
         Net sales                    $1,548.4 $1,507.3  $1,346.8  $1,309.1
         Cost of sales                   460.4    451.4     385.8     382.1
         Operating expenses              667.0    579.9     532.8     457.3
         Restructuring and special charge  -        -        10.0      56.0
         Acquired research                -        58.4       -         -
         Other income (loss) - net       (42.5)     9.2      42.3      19.1
         Income from:
            Continuing operations        269.6    295.6     319.2     300.7
            Discontinued operations       20.5     23.1      27.4      30.0
         Net income                      290.1    318.7     346.6     330.7

         Earnings per share:
            Continuing operations           .47      .51       .55       .52
            Discontinued operations         .03      .04       .05       .05
            Net income                      .50      .55       .60       .57
         Dividends paid per share           .3125    .3125     .3125     .3125
         Common stock prices:
            High                          33.13    29.63     29.44     30.94
            Low                           28.69    23.63     23.56     24.25

         (1)Per-share data and common stock prices  for all periods reflect
           the two-for-one stock split in 1995.  See Note 9 to consolidated
           financial statements.
         (2)Fourth-quarter income  from  continuing  operations  includes a
           benefit of  $42.1  million ($.08  per  share)  resulting from  a
           decline in the  1995 effective tax  rate from  29 percent  to 26
           percent.  Also, see Note 4 to  consolidated financial statements
           for a discussion of the  impact on earnings per  share resulting
           from the Guidant splitoff.
         (3)Reflects  the  impact  of  special   charges  relating  to  the
           voluntary recall of  three antibiotic products.   See Note  3 to
           the consolidated financial statements.

         The company's  common  stock is  listed  on the  New  York, Tokyo,
         London and other stock exchanges.


         Selected Financial Data (unaudited)
         ELI LILLY AND COMPANY AND SUBSIDIARIES
         (Dollars in millions, except per-share data)

                                   1995     1994     1993     1992     1991
                                 -------------------------------------------
                                                        
    Operations
    Net sales                     $6,763.8 $5,711.6 $5,198.5  $4,963.1 $4,533.4
    Research and development
       expenses                    1,042.3    838.7    755.0     731.0    590.5
    Other costs and expenses       3,739.7  3,136.4  2,780.4   2,664.5  2,412.0
    Restructuring and special 
       charges                        -        66.0  1,032.6     404.4     -
    Income from continuing operations
       before taxes and accounting
       changes                     1,765.6  1,698.6    662.8   1,193.5  1,626.3
    Income taxes                     459.0    513.5    198.0     351.0    460.2
    Income from continuing
       operations                  1,306.6  1,185.1    464.8     842.5  1,166.1
    Income (loss) from discontinued
       operations                    984.3    101.0     26.3     (14.9)   148.6
    Net income                     2,290.9  1,286.1    480.2     708.7  1,314.7
    Income from continuing
       operations as a percent
       of sales                       19.3%    20.7%     8.9%     17.0%    25.7%
    Per-share data1:
       Income from continuing
         operations                   $2.30    $2.05   $  .79     $1.43    $2.00
       Income (loss) from discontinued
         operations                    1.73      .17      .05      (.03)    .25
       Net income                      4.03     2.22      .82      1.20    2.25
       Dividends declared              1.33     1.26     1.22      1.128   1.025
    Average number of shares
       and share equivalents
       (thousands)1              569,026  578,378  588,578   588,956  588,488
                                 =======  =======  =======   =======  =======

    Financial Position
    Current assets                $4,138.6 $3,962.3 $3,697.1  $3,006.0 $2,939.3
    Current liabilities            4,967.0  5,669.5  2,928.0   2,398.6  2,272.0
    Property and equipment         4,239.3  4,411.5  4,200.2   4,072.1  3,782.5
    Total assets                  14,412.5 14,507.4  9,623.6   8,672.8  8,298.6
    Long-term debt                 2,592.9  2,125.8    835.2     582.3    395.5
    Other noncurrent liabilities   1,420.0  1,356.5  1,291.6     799.8    665.0
    Shareholders' equity           5,432.6  5,355.6  4,568.8   4,892.1  4,966.1
                                   =======  =======  =======   =======  =======

    Supplementary Data2
    Return on shareholders' equity    42.5%    25.9%    10.2%     14.4%    31.2%
    Return on assets                  15.6%    11.8%     5.2%      8.3%    17.2%
    Capital expenditures            $551.3   $576.5   $633.5    $912.9 $1,142.4
    Depreciation and amortization    553.7    432.2    398.3     368.1    299.5
    Effective tax rate                26.0%    30.2%    29.9%     29.4%    28.3%
    Number of employees             26,800   24,900   24,900    24,500   23,600
    Number of shareholders          52,600   55,900   59,300    53,900   46,000
                                    ======   ======   ======    ======   ======

         1 Per-share data  and  average  number  of  shares  have  been
          adjusted for all years to reflect  the two-for-one stock split
          in 1995.  Earnings per share for 1995  and 1994 are calculated
          based on  the weighted-average  number of  shares outstanding,
          while prior  years were  calculated on  a fully  diluted basis
          using average shares and share equivalents.  See Note 1 to the
          consolidated financial statements.

         2 All supplementary financial  data, other  than the  effective
          tax rate, have been computed using net  income.  The effective
          tax rate reflects continuing  operations only.  The  number of
          employees reflects employees of continuing operations only.


         Notes to Consolidated Financial Statements
         ELI LILLY AND COMPANY AND SUBSIDIARIES
         (Dollars in millions, except per-share data)

         Note 1:  Summary of Significant Accounting Policies

         Basis of Presentation:  The accounts  of all wholly owned  and
         majority-owned subsidiaries are  included in  the consolidated
         financial  statements.      All   intercompany  balances   and
         transactions  have  been  eliminated.     The  preparation  of
         financial statements  in  conformity  with generally  accepted
         accounting principles  requires management  to make  estimates
         and assumptions that  affect the  reported amounts  of assets,
         liabilities, revenues, expenses and related disclosures at the
         date of  the  financial statements  and  during the  reporting
         period.  Actual results could differ from those estimates.

         The number of shares  of common stock and  per-share data have
         been restated for all periods presented  to reflect the impact
         of the company's stock split (see Note 9).

         Cash Equivalents:   The company  considers all  highly liquid
         investments, generally  with  a maturity  of  three months  or
         less, to be cash  equivalents.  The cost  of these investments
         approximates fair value.

         Inventories:  The company states  all its  inventories at the
         lower of cost or market.  The company uses the last-in, first-
         out  (LIFO)  method  for  substantially  all  its  inventories
         located in the continental United States,  or approximately 54
         percent of  its  total  inventories.   Other  inventories  are
         valued by the first-in, first-out (FIFO)  method.  Inventories
         at December 31 consisted of the following:

                                              1995          1994
                                              ----          ----
         Finished products                 $  273.8      $  288.0
         Work in process                      446.4         515.1
         Raw materials and supplies           154.0         239.0
                                              -----       -------
                                              874.2       1,042.1
         Less reduction to LIFO cost           34.6          73.2
                                              -----       -------
                                           $  839.6      $  968.9
                                              =====       =======


         Investments:  All short-term debt securities are classified as
         held-to-maturity because the  company has the  positive intent
         and ability  to hold  the securities  to  maturity.   Held-to-
         maturity securities are stated at amortized cost, adjusted for
         amortization  of  premiums  and  accretion   of  discounts  to
         maturity.   Substantially all  long-term  debt and  marketable
         equity securities  are  classified  as  available-for-sale  at
         December 31, 1995.  Available-for-sale  securities are carried
         at fair value,  with the unrealized  gains and losses,  net of
         tax, reported in a separate component of shareholders' equity.
         The company  owns no  investments that  are  considered to  be
         trading securities.

         Intangible   Assets:      Intangible   assets   arising   from
         acquisitions and  research alliances are  amortized over their
         estimated useful lives, ranging from 5 to  40 years, using the
         straight-line method. Impairments are  recognized in operating
         results if a permanent decline in value occurs.


         Property and Equipment:   Property and equipment is  stated on
         the basis of cost.   Provisions for depreciation  of buildings
         and equipment are computed generally by the straight-line method
         at  rates based on their estimated  useful  lives.    At  December
         31,  property  and equipment consisted of the following:
                           
                                               1995           1994
                                               ----           ----

         Land                               $  136.1      $  163.5
         Buildings                           1,925.7       2,040.0
         Equipment                           3,990.5       4,060.9
         Construction in progress              776.0         762.0
                                             -------       -------
                                             6,828.3       7,026.4
         Less allowances for depreciation    2,589.0       2,614.9
                                             -------       -------
                                            $4,239.3      $4,411.5
                                             =======       =======

         Approximately $38.3 million,  $25.4 million and  $25.5 million
         of interest  costs were  capitalized as  part of  property and
         equipment in 1995, 1994 and 1993, respectively.  The estimated
         cost to complete significant construction projects in progress
         at December 31, 1995, approximated $199.1 million.   Total
         rental expense  for  all  leases related  to continuing operations,
         including  contingent   rentals (not  material), amounted to
         approximately $106.8  million for 1995, $81.8 million for 1994 and
         $80.1  million for 1993.  Capital leases included in property and
         equipment  in the consolidated balance sheets and future minimum
         rental commitments are not material.

         Income Taxes:   Deferred taxes are  recognized for  the future
         tax effects  of temporary  differences  between financial  and
         income tax  reporting based  on enacted  tax  laws and  rates.
         Federal income taxes are provided on the portion of the income
         of foreign subsidiaries that is expected to be remitted to the
         United States and be taxable.

         Earnings per Share:  Earnings per share for  1995 and 1994 are
         calculated based on the weighted-average number of outstanding
         common shares.  Earnings per share for 1993 is calculated on a
         fully diluted basis  based on  the weighted-average  number of
         outstanding  common  shares   and  common   share  equivalents
         (primarily stock options). Primary earnings per  share has not
         been  presented   for  1993   because  it   does   not  differ
         significantly from the reported earnings per share computed on
         a fully diluted basis.   Earnings per  share in 1995  and 1994
         are not materially different from the  amount calculated using
         the method followed for 1993.


         Note 2:  Acquisitions

         On December 18, 1995, the company  acquired Integrated Medical
         Systems, Inc.  (IMS),  a company  that  develops and  operates
         physician-focused  medical   communications  networks.     The
         purchase price  was approximately  $93 million,  consisting of
         cash  and  redeemable  securities.     Substantially  all  the
         purchase price was allocated to goodwill and other intangibles
         and will be amortized over 10 years.

         On  November  21,  1994,  the  company  purchased  PCS  Health
         Systems, Inc.  (PCS),  McKesson Corporation's  pharmaceutical-
         benefits-management business, for approximately  $4.1 billion.
         Substantially  all  the   purchase  price  was   allocated  to
         goodwill, which is being amortized over 40 years.

         The acquisition was structured  in the form of  a tender offer
         for all  McKesson's common  stock.   Immediately prior  to the
         tender offer, McKesson  spun off to  its shareholders  all its
         businesses other than  PCS.  In  connection with  the spinoff,
         the newly created corporation ("New McKesson") assumed all PCS
         liabilities not related  to the purchased  business, including
         approximately $239 million of long-term  notes and debentures.
         New McKesson has indemnified the company with respect to these
         liabilities and has  agreed that  it will,  if the  company so
         requests, seek consents from  the debt holders to  release the
         company from its obligations thereunder.  Pending repayment of
         the debt or  receipt of  releases from  the debt  holders, the
         company remains a co-obligor with New McKesson.

         The results of operations of PCS from  the date of acquisition
         are  included   in   the   company's  consolidated   financial
         statements.    The  following  unaudited   pro  forma  summary
         reflects the  company's consolidated  results from  continuing
         operations as if PCS had been acquired as  of the beginning of
         1993.  This summary includes the impact of adjustments for the
         amortization of goodwill  associated with the  acquisition and
         an increase in interest expense resulting from the issuance of
         debt to finance  the acquisition.   The pro forma  results are
         not  necessarily  indicative  of  what   actually  would  have
         occurred if the acquisition had been in  effect for the entire
         year, nor  are they  intended  to be  a  projection of  future
         results.

                           Year ended December 31     1994      1993
                                                   --------------------
    Net sales                                       $5,890.3   $5,372.0
    Income from continuing operations
      before accounting change                         989.2      246.8

    Earnings per share from continuing operations   $   1.71   $    .42


         On  September   9,   1994,   the   company   acquired   Sphinx
         Pharmaceuticals  Corporation,  a  company   engaging  in  drug
         discovery  and   development   by   generating   combinatorial
         chemistry libraries  of  small-molecule  compounds  and  high-
         throughput screening  against  biological  targets central  to
         human diseases.    The purchase  price  was approximately  $80
         million, of which  $58.4 million  was allocated  to in-process
         research and  development projects,  based  on an  independent
         valuation.  The company determined that the feasibility of the
         acquired research had  not yet been  established and  that the
         technology had no alternative  future use.   Accordingly, this
         acquired research was charged to expense in 1994.


         Note 3:  Restructuring and Special Charges

         In 1994, the  company incurred $66  million of  pretax charges
         associated with a voluntary recall of three of its liquid oral
         antibiotics.  The  recall was made  after four  instances were
         reported of small plastic caps being found in the antibiotics.
         Shipments of all three products were resumed during 1994.

         In both  1993 and  1992, the  company announced  major actions
         designed to  enhance  the  company's  competitiveness  in  the
         changing health care environment, reduce  expenses and improve
         efficiencies.   As  a result  of  these  actions, the  company
         recognized  restructuring  and  special  charges  relating  to
         continuing operations of  $1,032.6 million and  $404.4 million
         for 1993 and 1992, respectively.   Restructuring costs include
         those amounts that  arose as a  direct result  of management's
         commitment to  revised  strategic  actions.   Special  charges
         represent unusual, generally nonrecurring, expense items.

         Significant components of  these charges  and their  status at
         December 31, 1994  and 1995,  respectively, are  summarized as
         follows:

                                         Original
                                         Charges      1994      1995
                                         ----------------------------
         1993
         ----
         Work force reductions          $  534.5   $ 52.5   $ 37.7
         Manufacturing consolidations
            and other closings             204.3    136.1    125.2
         Pharmaceutical streamlining        35.3     23.8      6.3
         Asset write-downs, legal
            accruals and other             258.5     39.9     30.2
                                          ------     -----    -----
         Total - continuing             $1,032.6   $252.3   $199.4
                                         -------    -----    -----
         1992
         ----
         Global manufacturing strategy  $  218.9   $108.4   $ 87.3
         Legal, environmental,
            asbestos abatement             139.4     66.8     65.4
         Research investment expense        46.1       -        -
                                           -----     -----    -----
         Total - continuing operations  $  404.4   $175.2   $152.7
                                          -------    -----    -----

         The 1993 restructuring  actions consisted primarily  of early-
         retirement and other  severance programs associated  with work
         force reductions, as well as  streamlining core pharmaceutical
         operations.  In addition,  restructuring actions in  both 1993
         and 1992 have  resulted or will  result in a  consolidation of
         certain manufacturing  operations and  changes  in the  nature
         and/or location  of certain  manufacturing operations.   Asset
         write-downs  reflected  changes  in   pharmaceutical  markets.
         Special  charges  were  established  for  patent  and  product
         liability matters in both 1993 and 1992.


         Note 4:  Discontinued Operations

         During 1995, the company completed the divestiture of the nine
         Medical Devices and Diagnostics (MDD) Division businesses.  In
         1994, a separate  company, Guidant Corporation  (Guidant), was
         formed to be the parent company of five  of the MDD companies:
         Advanced Cardiovascular  Systems,  Inc.;  Cardiac  Pacemakers,
         Inc.; Devices  for Vascular  Intervention, Inc.;  Heart Rhythm
         Technologies, Inc.; and Origin  Medsystems, Inc.   In December
         1994, Guidant  sold  approximately 20  percent  of its  common
         stock in an initial  public offering.  In  September 1995, the
         company distributed  its  remaining  80  percent  interest  in
         Guidant through  a  splitoff (an  exchange  offer pursuant  to
         which Lilly  shareholders  could  exchange  Lilly  shares  for
         Guidant shares).  Pursuant to the  splitoff, 16,504,298 shares
         of the company's common stock (expressed  on a pre-stock-split
         basis) were  exchanged for  the Guidant  stock.   The splitoff
         resulted in  a  tax-free  gain  calculated as  the  difference
         between the  market  and  carrying  values  of the  shares  of
         Guidant common  stock held  by the  company on  the expiration
         date of  the  exchange  offer.   Sales  of  three of  the  MDD
         companies,  IVAC  Corporation,  Pacific   Biotech,  Inc.,  and
         Physio-Control Corporation,  were  completed  during 1994  and
         1995,  and  the  divestiture  of  Hybritech  Incorporated  was
         finalized in January 1996.

         The income  from  discontinued  operations  appearing  on  the
         consolidated statements  of income  represents the  results of
         the MDD division  for the periods  presented and the  net gain
         upon divestiture and is summarized as follows:

                                                Year ended December 31
                                            ------------------------------
                                            1995      1994      1993
                                            ----      ----      ----

      Net sales                            $ 771.6  $1,289.2 $1,254.0

      Cost of sales                          258.2     536.6    511.3
      Restructuring and special charges        -         -      140.1
      Other operating expenses               356.8     561.5    580.8
      Income before tax                      111.9     168.1     39.0

      Income from operations, net of tax      62.8     101.0     26.3
      Net gain on disposition, net of tax
         ($88.1 million)                     921.5       -         -
                                             -----     -----     -----
      Discontinued operations              $ 984.3   $ 101.0  $  26.3
                                             =====     =====    =====

         At December 31,  1994, net  assets of  discontinued operations
         aggregated  $441.7   million   and   were  included   in   the
         consolidated balance  sheet.    Due  to the  disposition,  all
         assets, liabilities and equity of the MDD businesses have been
         removed from the company's balance sheet at December 31, 1995.

         The shares  of the  company's common  stock  exchanged in  the
         splitoff resulted  in a  reduction in  the  average number  of
         shares outstanding used to calculate earnings per share.  As a
         consequence, earnings per share from continuing operations for
         the fourth  quarter  and  year  were  $.03  and  $.04  higher,
         respectively, than had the splitoff not occurred.

         Note 5:  Accounting Changes

         In March  1995, Statement  of  Financial Accounting  Standards
         (SFAS) No. 121, "Accounting  for the Impairment  of Long-Lived
         Assets and  for  Long-Lived Assets  to  be  Disposed Of,"  was
         issued.  The statement must  be adopted by the  company in the
         first quarter  of  1996. Under  provisions  of the  statement,
         impairments, measured using fair market  value, are recognized
         whenever events or changes in circumstances  indicate that the
         carrying amount of  long-lived assets  may not  be recoverable
         and the  future undiscounted  cash flows  attributable  to the
         asset are less than its carrying value.   The statement is not
         expected to have a material impact on the company's results of
         operations or financial position.

         In October 1995, SFAS No. 123, "Stock Based Compensation," was
         issued.   This statement  will require  the company  to choose
         between two different methods of accounting for stock options.
         The statement defines a fair- value-based method of accounting
         for stock options but allows an entity  to continue to measure
         compensation cost  for  stock  options  using  the  accounting
         prescribed by  APB Opinion  No. 25  (APB 25),  "Accounting for
         Stock Issued  to Employees."   Use  of the  APB 25  accounting
         method results  in no  compensation cost  being recognized  if
         options are granted at an exercise price at the current market
         value of  the stock.   The  company will  continue to  use the
         intrinsic value method  under APB 25  but will be  required by
         SFAS 123  to make  pro  forma disclosures  of  net income  and
         earnings per  share  as  if the  fair  value  method had  been
         applied in its 1996 financial statements.

         Effective January 1, 1993,  the company adopted SFAS  No. 112,
         "Employers' Accounting for Postemployment Benefits."  SFAS 112
         requires employers  to recognize  currently the  obligation to
         provide  postemployment  benefits   for  former   or  inactive
         employees and  others.   The company's  adoption  of SFAS  112
         resulted in a  pretax charge of  $17.3 million  ($10.9 million
         after tax; $.02 per  share), relating primarily  to disability
         benefits.    Prior  to   1993,  the  company   expensed  these
         obligations when paid.


         Note 6:  Financial Instruments

         Risk-Management Instruments and Off-Balance-Sheet Risk

         In the normal course of business, operations of the company are
         exposed to  continuing  fluctuations  in  currency  values  and
         interest rates.    These  fluctuations can  vary  the  costs of
         financing, investing  and  operating.    The company  addresses
         these risks  through a  controlled program  of  risk management
         that includes the use of derivative financial instruments.  The
         company's derivative activities, all of  which are for purposes
         other than  trading,  are initiated  within  the  guidelines of
         documented corporate risk-management policies and do not create
         risk because gains  and losses  on derivative  contracts offset
         losses and gains  on the  assets, liabilities  and transactions
         being hedged.

         The notional amounts of derivatives summarized in the following
         paragraphs do not  represent amounts  exchanged by  the parties
         and thus  are not  a measure  of  the exposure  of  the company
         through its  use of  derivatives.   The  company is  exposed to
         credit-related  losses  in  the   event  of  nonperformance  by
         counterparties to financial instruments, but it does not expect
         any counterparties  to  fail to  meet  their  obligations given
         their high credit ratings.

         Foreign Exchange  Risk  Management:   The  company  enters into
         ----------------------------------
         foreign currency  forward and  option contracts  to  reduce the
         effect of  fluctuating  currency  exchange  rates  (principally
         European currencies  and  the  Japanese yen)  on  two  types of
         foreign currency exposures.   Exposures arising  from affiliate
         foreign currency balances  are managed principally  through the
         use of forward contracts.  These contracts are marked to market
         with gains and losses recognized currently  in income to offset
         the respective losses  and gains  recognized on  the underlying
         exposures.  The  company also  enters into option  contracts to
         hedge  anticipated  foreign  currency  transactions,  primarily
         intercompany inventory purchases  expected to occur  within the
         next year, and foreign currency  forward contracts and currency
         swaps to hedge  firm commitments.   Gains  and losses  on these
         contracts that qualify as hedges are deferred and recognized as
         an adjustment  of the  subsequent transaction  when  it occurs.
         Forward and  option  contracts  generally  have maturities  not
         exceeding 12 months.

         At December  31,  the  stated,  or  notional,  amounts  of  the
         company's outstanding  foreign  currency  derivative  financial
         instruments were as follows:

                                                     1995       1994
                                                     ----       ----

         Forward exchange contracts                $ 838.2    $ 1,138.1
         Foreign currency options - purchased        415.2         98.6
         Foreign currency options - issued              -          62.6
         Currency swaps                                 -          20.4

         Interest Rate Risk Management:  See discussion on interest rate
         -----------------------------
         swaps in Note 7.


         Concentrations of  Credit Risk:   Financial  instruments that
         ------------------------------
         potentially  subject  the  company  to   credit  risk  consist
         principally  of   trade   receivables   and   interest-bearing
         investments.  Wholesale distributors of life-sciences products
         and  managed-care  organizations  account  for  a  substantial
         portion of  trade  receivables;  collateral is  generally  not
         required.   The  risk associated  with  this concentration  is
         limited due  to  the large  number  of  wholesalers and  their
         geographic dispersion.

         The company  places  substantially  all  its  interest-bearing
         investments  with  major   financial  institutions,   in  U.S.
         Government securities or with top-rated corporate issuers.  In
         accordance with  documented  corporate  policies, the  company
         limits the  amount of  credit exposure  to  any one  financial
         institution.


         Fair Value of Financial Instruments

         A summary of  the company's outstanding  financial instruments
         at December  31 follows.   As  summarized,  "cost" relates  to
         investments while "carrying amount" relates to long-term debt.
                                          1995                1994
                                 -------------------------------------------
                                 Cost/Carrying   Fair   Cost/Carrying   Fair
                                    Amount      Value     Amount       Value
                                    ------      -----     ------       -----
         Short-term investments:
            Debt securities        $ 84.6      $ 85.0     $191.4       $195.1
            Marketable equity          -           -        19.1         18.4

         Noncurrent investments:
           Marketable equity         66.1       140.3       80.5         74.9
           Debt securities          143.0       148.0      163.0        159.7
           Nonmarketable equity      34.5        35.3       30.0         31.3

         Long-term debt           2,734.3     2,885.6    2,206.8      2,147.1

         The company  determines  fair values  based  on quoted  market
         values  where  available  or  discounted  cash  flow  analyses
         (principally  long-term   debt).      The   fair   values   of
         nonmarketable equity securities, which represent either equity
         investments in start-up  technology companies  or partnerships
         that invest  in start-up  technology companies,  are estimated
         based  on  the  fair  value  information   provided  by  these
         ventures.   The  fair  value  and  carrying  amount  of  risk-
         management instruments were not material at  December 31, 1995
         or 1994.

         At December 31,  1995 and 1994,  the gross  unrealized holding
         gains on available-for-sale securities were  $88.2 million and
         $22.2 million, respectively, and the  gross unrealized holding
         losses were  $8.2  million  and $27.0  million,  respectively.
         Substantially all these gains  and losses are  associated with
         the marketable equity securities.  The  proceeds from sales of
         available-for-sale securities totaled $46.0  million and $24.3
         million in 1995  and 1994, respectively.   Realized  gains and
         losses and purchases of available-for-sale securities were not
         significant  in  1995  and  1994.     The  net  adjustment  to
         unrealized gains and  losses on  available-for-sale securities
         increased (reduced) shareholders' equity by  $52.9 million and
         ($13.7 million) in 1995 and 1994, respectively.

         The company is a limited partner in certain affordable housing
         investments that generate benefits in the form of tax credits.
         The determination of  fair value of  these investments  is not
         practicable.   The  carrying  value  of such  investments  was
         $250.2 million and $194.9 million as of  December 31, 1995 and
         1994, respectively.

         Effective January 1,  1994, the  company adopted  Statement of
         Financial Accounting Standards (SFAS) No. 115, "Accounting for
         Certain Investments  in  Debt  and Equity  Securities,"  which
         requires designation of certain investments as either trading,
         held-to-maturity or available-for-sale.   As a  consequence of
         the adoption,  all available-for-sale  securities  on hand  at
         January 1, 1994, were marked to market and the opening balance
         of shareholders' equity was increased by $10.7 million (net of
         $7.0 million  in deferred  income taxes)  to  reflect the  net
         unrealized holding gains on these securities at that date.

         On November 15, 1995, the Financial Accounting Standards Board
         staff issued a Special  Report, "A Guide to  Implementation of
         Statement 115 on  Accounting for  Certain Investments  in Debt
         and Equity Securities."  In accordance with provisions in that
         Special  Report,  the  company  chose  to  reclassify  certain
         securities from  held-to-maturity to  available-for-sale.   At
         the date of transfer,  the amortized cost of  those securities
         was $139.6  million  and  the  net  unrealized gain  on  those
         securities  was   $5.0   million,   which   is   included   in
         shareholders' equity.


         Note 7:  Borrowings

         Long-term debt at December 31 consisted of the following:

                                                      1995     1994
                                                  ---------------------

     6.25 to 8.38 percent notes (due 1999-2006)      $  750.0  $  750.0
     7.13 percent notes (due 2025)                      500.0      -
     6.09 to 8.06 percent medium-term notes
        (due 1996-1999)                                 185.8     210.8
     5.50 to 8.38 percent Eurodollar bonds
        (due 1998-2005)                                 500.0     150.0
     8.18 percent ESOP debentures (due 2006)            128.8     143.7
     6.07 to 6.47 percent Guidant notes (due 1996)        -       473.0
     Commercial paper to be refinanced as long-term     500.0     350.0
     Other, including capitalized leases                211.0     140.8
                                                      -------   -------
                                                      2,775.6   2,218.3
     Less current portion                               182.7      92.5
                                                      -------   -------
                                                     $2,592.9  $2,125.8
                                                      =======   =======

         The company's  acquisition of  PCS (see  Note 2)  was financed
         primarily through the issuance  of $3.8 billion  in commercial
         paper.  Through December  1995, the company had  replaced $1.3
         billion of the commercial paper with long-term debt, including
         the 1995  issuance  of  $350  million  of Eurobonds  and  $500
         million of 30 year  notes with a 7.9  percent weighted-average
         effective interest  rate.    Further,  in  January  1996,  the
         company replaced another $500 million of  the commercial paper
         through issuance of 20 and  40 year notes at  6.57 percent and
         6.77 percent, respectively.   Accordingly, this item  has been
         classified as long-term debt at December 31, 1995.

         The company enters into  interest rate swaps to  lower funding
         costs, to diversify  sources of funding  or to  alter interest
         rate exposures  arising  from  mismatches between  assets  and
         liabilities.   The  notional amounts  of  interest rate  swaps
         outstanding at December 31,  1995 and 1994, were  $280 million
         and  $175  million,  respectively.     Substantially  all  the
         interest rate  swaps outstanding  at December  31, 1995,  were
         closed out in January 1996.

         The  8.18  percent   Employee  Stock  Ownership   Plan  (ESOP)
         debentures are obligations  of the ESOP  but are shown  on the
         consolidated balance sheet because they are  guaranteed by the
         company.   The principal  and  interest on  the  debt will  be
         funded by  contributions  from the  company  and by  dividends
         received on certain shares held  by the ESOP.   Because of the
         amortizing feature of the ESOP debt,  bondholders will receive
         both interest and principal payments each quarter.

         The Guidant  notes  outstanding  on  December 31,  1994,  were
         retained by Guidant following  the splitoff in  September 1995
         (see Note 4).   The company  is no longer  a guarantor  of any
         Guidant obligations.

         The aggregate amounts of maturities on  long-term debt for the
         next five years  are as follows:  1996, $182.7  million; 1997,
         $110.7 million;  1998, $173.1  million; 1999,  $153.6 million;
         and 2000, $216.9 million.

         At December 31, 1995, short-term  borrowings included $1,626.3
         million of commercial paper and $99.8 million of notes payable
         to banks.   At December 31,  1994, commercial paper  and notes
         payable to banks totaled $2,364.9 million  and $267.0 million,
         respectively.  The  weighted-average interest rates  on short-
         term borrowings outstanding were  5.8 percent in 1995  and 6.0
         percent in 1994.  At December 31, 1995, unused committed lines
         of credit  totaled  $3  billion.   Compensating  balances  and
         commitment fees are not material, and  there are no conditions
         that are probable  of occurring under  which the lines  may be
         withdrawn.

         Cash  payments  of  interest  on   borrowings  totaled  $271.7
         million, $102.4 million  and $63.7 million  in 1995,  1994 and
         1993, respectively.


         Note 8:  Stock Plans

         Stock options  and  performance awards  have  been granted  to
         officers and other executive and key employees.  Stock options
         are granted at prices equal to 100 percent  of the fair market
         value at the dates of grant.

         In October 1995, the company issued its second grant under the
         GlobalShares program,  under which  essentially all  employees
         were given an option to buy 200 shares of the company's common
         stock at a price equal to the fair market value at the date of
         grant.  Options to  purchase approximately 5.2  million shares
         were granted under the program.

         Stock-option activity during 1995 and 1994 is summarized below:

                                                  Number of Shares
                                                   1995      1994
                                              ------------------------

         Unexercised at January 1............ 31,081,360   28,903,636
         Granted............................. 10,770,663    5,727,444
         Exercised........................... (2,892,178)  (2,583,370)
         Terminated.......................... (1,343,050)    (966,350)
                                              ----------   ----------
         Unexercised at December 31           37,616,795   31,081,360
                                              ==========   ==========
         Exercisable at December 31           13,396,245   13,823,060
                                              ==========   ==========

         The per-share price range  of unexercised options  at December
         31, 1995 and 1994,  was $6.55 to  $46.82 and $7.27  to $40.94,
         respectively.  Options were  exercised at prices  ranging from
         $7.27 to  $40.94  in  1995 ($4.57  to  $23.53  in 1994).    At
         December 31, 1995,  additional options, performance  awards or
         restricted stock grants  may be granted  under the  1994 Lilly
         Stock  Plan  for  not  more  than   7,366,003  shares  (1994--
         17,037,366 shares).


         Note 9:  Shareholders' Equity

Changes in the components of shareholders' equity were as follows: Additional Deferred Common Stock in Paid-in Retained Costs-- Treasury --------------- Capital Earnings ESOP Shares Amount -------- -------- -------- --------------- Balance at January 1, 1993 $ 307.9 $4,743.1 $(263.9) 122,120 $ 7.8 Net income 480.2 Cash dividends declared per share: $1.22 (715.7) Purchase for treasury 550,000 29.8 Issuance of stock under employee stock plans (16.3) (585,103) (32.5) ESOP transactions 3.6 21.1 Other (0.6) (6.7) (27,740) (1.7) ------ ------ ------ ------ ---- Balance at December 31, 1993 294.6 4,500.9 (242.8) 59,277 3.4 Net income 1,286.1 Cash dividends declared per share: $1.26 (728.6) Purchase for treasury 1,990,000 115.0 Issuance of stock under employee stock plans (12.0) (1,162,516) (62.5) ESOP transactions (0.2) 24.6 Unrealized investment gains and losses, net of tax (3.0) Net impact of Guidant public offering 139.9 Other (0.6) 6.7 (15,247) (0.9) ------ ---- ----- ------ --- Balance at December 31, 1994 421.7 5,062.1 (218.2) 871,514 55.0 Net income 2,290.9 Cash dividends declared per share: $1.33 (747.8) Stock dividend declared (172.6) Purchase for treasury 2,630,000 160.0 Increase in treasury shares from Guidant exchange transaction (Note 4) 10.9 16,504,298 1,533.6 Issuance of stock under employee stock plans (24.1) (1,841,175) (122.0) ESOP transactions 9.9 18.7 Unrealized investment gains and losses, net of tax 52.9 Other (0.1) (1.2) (15,143) (1.1) ---- ---- ---- ------ ---- Balance at December 31, 1995 $418.3 $6,484.3 $(199.5) 18,149,494 $1,625.5 ===== ======= ======= ========= =======
On October 16, 1995, the company's board of directors declared a two-for-one stock split to be effected in the form of a 100 percent stock dividend payable to shareholders of record at the close of business November 15, 1995. The outstanding and weighted-average number of shares of common stock and per-share data in these financial statements have been restated to reflect the impact of the stock split for all years presented. The company now has 568,902,054 issued shares of common stock without par value, including 276,094,410 shares issued December 20, 1995, as a result of the stock split. Treasury shares held by the company were not split. The company has an Employee Stock Ownership Plan (ESOP) as a funding vehicle for the existing employee savings plan. The ESOP used the proceeds of a loan from the company to purchase shares of common stock from the treasury. In 1991, the ESOP issued $200 million of third-party debt, repayment of which was guaranteed by the company (see Note 7). The proceeds were used to purchase shares of the company's common stock on the open market. Shares of common stock held by the ESOP will be allocated to participating employees annually through 2006 as part of the company's savings plan contribution. The fair value of shares allocated each period is recognized as compensation expense. The increase in paid-in capital during 1994 related to the Guidant initial public offering reflects net proceeds of the offering reduced by the resulting minority ownership interest in Guidant. Generally, the assets and liabilities of foreign operations are translated into U.S. dollars using the current exchange rate. For those operations, changes in exchange rates generally do not affect cash flows; therefore, resulting translation adjustments are made to shareholders' equity rather than to income. Following is an analysis of currency translation adjustments reflected in shareholders' equity: 1995 1994 1993 ---------------------- Balance at January 1 $(38.0) $(163.5) $(70.2) Translation adjustments 37.4 125.5 (93.3) ----- ----- ----- Balance at December 31 $ (0.6) $ (38.0) $(163.5) ===== ===== ===== Under the terms of the company's Shareholder Rights Plan, all shareholders of common stock received for each share owned a preferred stock purchase right entitling them to purchase from the company one four-hundredth of a share of Series A Participating Preferred Stock at an exercise price of $81.25. The rights are not exercisable until after the date on which the company's right to redeem has expired. The company may redeem the rights for $.0025 per right up to and including the 10th business day after the date of a public announcement that a person (the "Acquiring Person") has acquired ownership of stock having 20 percent or more of the company's general voting power (the "Stock Acquisition Date"). The plan provides that, if the company is acquired in a business combination transaction at any time after a Stock Acquisition Date, generally each holder of a right will be entitled to purchase at the exercise price a number of the acquiring company's shares having a market value of twice the exercise price. The plan also provides that, in the event of certain other business combinations, certain self-dealing transactions, or the acquisition by a person of stock having 25 percent or more of the company's general voting power, generally each holder of a right will be entitled to purchase at the exercise price a number of shares of the company's common stock having a market value of twice the exercise price. Any rights beneficially owned by an Acquiring Person shall not be entitled to the benefit of the adjustments with respect to the number of shares described above. The rights will expire on July 28, 1998, unless redeemed earlier by the company. Note 10: Income Taxes Following is the composition of income taxes attributable to continuing operations: 1995 1994 1993 ---- ---- ---- Current: Federal $ 177.0 $ 244.9 $ 296.5 Foreign 140.1 60.2 81.6 State 3.8 30.9 26.7 ----- ----- ----- 320.9 336.0 404.8 Deferred: Federal 114.2 140.4 (81.9) Foreign 1.9 1.9 (89.6) State 22.0 35.2 (35.3) ---- ---- ---- 138.1 177.5 (206.8) ----- ----- ----- Income taxes $ 459.0 $ 513.5 $ 198.0 ===== ===== ===== Significant components of the company's deferred tax assets and liabilities as of December 31 are as follows: 1995 1994 ---- ---- Deferred tax assets: Restructuring and special charges $ 164.7 $ 283.4 Compensation and benefits 148.4 154.2 Divestiture related 143.6 - Litigation, environmental and asbestos 95.3 141.6 Inventory 90.5 77.6 Net operating losses of subsidiaries 63.9 69.4 Other 202.2 216.7 ------ ------ 908.6 942.9 Valuation allowances (85.9) (97.9) ------ ------ Total deferred tax assets 822.7 845.0 Deferred tax liabilities: Property and equipment (519.7) (490.7) Prepaid employee benefits (200.7) (181.4) Other (77.0) (50.1) ------ ------ Total deferred tax liabilities (797.4) (722.2) ------ ------ Deferred tax assets--net $ 25.3 $ 122.8 ====== ====== At December 31, 1995, the company had net operating loss carryforwards for income tax purposes of $175 million, of which $29 million will expire within five years. Approximately one- third of the remaining carryforwards do not expire. Unremitted earnings of foreign subsidiaries that have been, or are intended to be, permanently reinvested for continued use in foreign operations and which, if distributed, would result in taxes at approximately the U.S. statutory rate, aggregated $1,544 million at December 31, 1995 ($1,216 million at December 31, 1994). Cash payments of taxes totaled $449 million, $378 million and $455 million in 1995, 1994 and 1993, respectively. Following is a reconciliation of the effective income tax rate of the continuing operations: 1995 1994 1993 ---- ---- ---- United States federal statutory tax rate 35.0% 35.0% 35.0% Add (deduct): State taxes, net of federal tax benefit .9 2.5 (.9) Tax savings from operations in Puerto Rico (4.2) (2.1) (9.7) General business credits (1.2) (0.5) (2.1) Effect of international operations (5.7) (3.7) 1.9 Nondeductible goodwill amortization 2.1 0.3 .3 Nondeductible impact of restructuring - - 3.0 Sundry (.9) (1.3) 2.4 ----- ---- ---- Effective income tax rate 26.0% 30.2% 29.9% ==== ==== ==== Note 11: Retirement Benefits Pension Plans: The company has noncontributory defined benefit retirement plans that cover substantially all United States employees and a majority of employees in other countries. Benefits under the domestic plans are calculated by using one of several formulas. These formulas are based on a combination of the following: (1) years of service, (2) final average earnings, (3) primary social security benefit and (4) age. The benefits for the company's plans in countries other than the United States are based on years of service and compensation. The company's funding practice for all plans is consistent with local governmental and tax funding regulations. Generally, pension costs accrued are funded. Plan assets consist primarily of equity and fixed income instruments. Net pension expense/income for the company's retirement plans included the following components related to continuing operations: 1995 1994 1993 ---- ---- ---- Service cost--benefits earned during the year $ 69.8 $ 69.3 $ 58.9 Interest cost on projected benefit obligations 160.2 156.3 124.6 Actual return on assets (434.8) (38.3) (276.4) Net amortization and defferal 227.4 (164.3) 88.6 ------ ------ ------ Net annual pension expense (income) $ 22.6 $ 23.0 $ (4.3) ====== ====== ===== The increase in the 1994 net annual pension expense was due primarily to the decrease in the discount rate at December 31, 1993. In addition to the net pension cost above, the 1993 restructuring charges include curtailment losses and special termination costs resulting from the early-retirement programs of $133.3 million and $113.4 million, respectively. The funded status and amounts recognized in the consolidated balance sheets for the company's defined benefit retirement plans at December 31 were as follows: Plans in Which Plans in Which Assets Exceed Accumulated Benefits Accumulated Benefits Exceed Assets 1995 1994 1995 1994 ---------------------------------------- Plan assets at fair value $2,374.4 $2,066.4 $ 4.2 $ - Actuarial present value of benefit obligations: Vested benefits 1,682.3 1,511.5 119.2 88.5 Nonvested benefits 100.0 96.0 4.0 1.2 ------- ------- ----- ---- Accumulated benefit obligation 1,782.3 1,607.5 123.2 89.7 Effect of projected future salary increases 320.9 258.2 9.4 10.1 ------- ------- ----- ---- Projected benefit obligation 2,103.2 1,865.7 132.6 99.8 ------- ------- ----- ----- Funded status 271.2 200.7 (128.4) (99.8) Unrecognized net (gain) loss 114.3 100.2 8.1 (8.5) Unrecognized prior service cost 96.7 111.2 16.2 13.7 Unrecognized net obligation at January 1, 1986 2.0 1.8 1.8 2.4 Additional minimum liability - - (20.1) - ------- ------- -------- ------- Prepaid (accrued) pension cost $ 484.2 $ 413.9 $ (122.4) $(92.2) ======= ======= ======= ====== The assumptions used to develop net periodic pension expense from continuing operations and the actuarial present value of projected benefit obligations are shown below: (percents) 1995 1994 1993 ---- ---- ---- Weighted-average discount rate 7.6 8.6 7.6 Rate of increase in future compensation levels 4.5-9.5 4.5-9.5 4.5-9.5 Weighted-average expected long-term rate of return on plan assets 10.5 10.9 11.0 The discount rate decrease at December 31, 1995, increased the projected benefit obligation by approximately $231.6 million. The company has defined contribution savings plans that cover its eligible employees worldwide. The purpose of these defined contribution plans is generally to provide additional financial security during retirement by providing employees with an incentive to make regular savings. Company contributions to the plans are based on employee contributions and the level of company match. Expenses attributable to continuing operations under the plans totaled $38.3 million, $37.9 million and $24.7 million for the years 1995, 1994 and 1993, respectively. Retiree Health Benefits: The company's noncontributory defined benefit postretirement plans provide health benefits for the majority of the United States retirees and their eligible dependents. Certain of the company's non-U.S. subsidiaries have similar plans for retirees. Eligibility for these benefits is based upon retirement from the company. An eligible employee's credited service period begins when the combination of an employee's age and years of service equals 60. The company's funding practice for all plans is consistent with local governmental and tax funding regulations. Plan assets consist primarily of equity and fixed income instruments. Net postretirement benefit expense from continuing operations included the following components: 1995 1994 1993 ---- ---- ---- Service cost--benefits earned during the year $ 9.8 $ 11.4 $ 10.7 Interest cost on accumulated postretirement benefit obligations 24.7 25.9 19.8 Actual return on assets (20.4) 1.1 (11.2) Net amortization and deferral (4.9) (23.3) (10.2) ----- ----- ----- Net periodic postretirement benefit cost $ 9.2 $ 15.1 $ 9.1 ===== ===== ===== In connection with the company's early-retirement programs in 1993, restructuring charges include curtailment and termination costs relating to these plans of $52.4 million and $7.0 million, respectively. The funded status and amounts recognized in the consolidated balance sheets for the company's defined benefit postretirement plans at December 31 were as follows: 1995 1994 ---- ---- Accumulated postretirement benefit obligation: Retirees $308.3 $231.5 Fully eligible active plan participants 26.5 19.4 Other active plan participants 59.8 53.7 ---- ----- 394.6 304.6 Plan assets at fair value 168.2 147.0 ----- ----- Accumulated postretirement benefit obligation in excess of plan assets 226.4 157.6 Unrecognized benefit of plan amendment 20.6 29.2 Unrecognized net loss (99.2) (13.9) ----- ----- Accrued postretirement benefit cost $147.8 $172.9 ----- ----- The assumptions used to develop the net postretirement benefit expense from continuing operations and the present value of the accumulated postretirement benefit obligations are shown below: (percents) 1995 1994 1993 ---- ---- ---- Weighted-average discount rate 7.5 8.5 7.5 Expected long-term rate of return 10.5 11.0 11.0 Health care cost trend rate for participants: Under age 65 7.0 8.0 8.0 Over age 65 5.0 6.0 6.0 If these trend rates were to be increased by 1 percentage point each future year, the December 31, 1995, accumulated postretirement benefit obligation would increase by 11 percent and the aggregate of the service and interest cost components of 1995 annual expense from continuing operations would increase by 14 percent. The decrease in the discount rate at December 31, 1995, increased the accumulated postretirement benefit obligation by approximately $36.3 million. Note 12: Contingencies The company has been named as a defendant in numerous product liability lawsuits involving primarily two products, diethylstilbestrol and Prozac. The company has accrued for its estimated exposure, including costs of litigation, with respect to all current product liability claims. In addition, the company has accrued for certain future anticipated product liability claims to the extent the company can formulate a reasonable estimate of their costs. The company's estimates of these expenses are based primarily on historical claims experience and data regarding product usage. The company expects the cash amounts related to the accruals to be paid out over the next several years. The majority of costs associated with defending and disposing of these suits are covered by insurance. The company's estimate of insurance recoverables is based on existing deductibles, coverage limits, and the existing and projected future level of insolvencies among its insurance carriers. Under the Comprehensive Environmental Response, Compensation, and Liability Act, commonly known as Superfund, the company has been designated as one of several potentially responsible parties with respect to certain sites. Under Superfund, each responsible party may be jointly and severally liable for the entire amount of the cleanup. The company also continues remediation of certain of its own sites. The company has accrued for estimated Superfund cleanup costs, remediation and certain other environmental matters, taking into account, as applicable, available information regarding site conditions, potential cleanup methods, estimated costs and the extent to which other parties can be expected to contribute to those costs. The company has asserted its right to insurance coverage for certain environmental liabilities and has reserved its right to pursue claims for insurance with respect to certain other environmental liabilities. However, because of uncertainties with respect to the timing and ultimate realization of those claims, the company has not recorded any environmental insurance recoverables. The company has been named, along with numerous other U.S. prescription drug manufacturers, as a defendant in a large number of related actions brought by retail pharmacies alleging violations of federal and state antitrust and pricing laws. The federal suits include a class action on behalf of the majority of U.S. retail pharmacies alleging an industrywide agreement to deny favorable prices to retail pharmacies. The company and 11 other manufacturers have agreed to settle the federal class action case. The anticipated settlement amount was accrued in the fourth quarter of 1995. The settlement is subject to approval of the district court. Other related suits, brought by several thousand pharmacies in federal court and courts in four states, involve claims of price discrimination or claims under other pricing laws. Additional cases have been brought on behalf of consumers in eight states. The environmental liabilities and litigation accruals have been reflected in the company's consolidated balance sheet at a gross amount of approximately $342 million. Estimated insurance recoverables of approximately $140 million have been reflected as assets in the consolidated balance sheet. While it is not possible to predict or determine the outcome of the product liability, antitrust or other legal actions brought against the company or the ultimate cost of environmental matters, the company believes the costs associated with all such matters will not have a material adverse effect on its consolidated financial position or liquidity but could possibly be material to the consolidated results of operations in any one accounting period. Responsibility for Financial Statements Eli Lilly and Company and Subsidiaries The consolidated financial statements and related notes have been prepared by management, who are responsible for their integrity and objectivity. The statements have been prepared in accordance with generally accepted accounting principles and include amounts based on judgments and estimates by management. The other financial information in this annual report is consistent with that in the financial statements. The company maintains internal accounting control systems that are designed to provide reasonable assurance that assets are safeguarded, that transactions are executed in accordance with management's authorization and are properly recorded and that accounting records are adequate for preparation of financial statements and other financial information. The design, monitoring and revision of internal accounting control systems involve, among other things, management's judgments with respect to the relative cost and expected benefits of specific control measures. A staff of internal auditors regularly monitors, on a worldwide basis, the adequacy and effectiveness of internal accounting controls. In addition to the system of internal accounting controls, the company maintains guidelines of company policy emphasizing proper overall business conduct, possible conflicts of interest, compliance with laws and confidentiality of proprietary information. The guidelines are reviewed on a periodic basis with members of management worldwide. The financial statements have been audited by Ernst & Young LLP, independent auditors. Their responsibility is to examine the company's financial statements in accordance with generally accepted auditing standards and to express their opinion with respect to the fairness of presentation of the statements. The members of the audit committee of the board of directors, none of whom are employees of the company, recommend independent auditors for appointment by the board of directors, review the services performed by the independent auditors, and receive and review the reports submitted by them. The audit committee meets several times during the year with management, the internal auditors and the independent auditors to discuss audit activities, internal controls and financial reporting matters. The internal auditors and the independent auditors have full and free access to the committee. Randall L. Tobias Sidney Taurel Chairman of the Board and Executive Vice President and Chief Executive Officer Acting Chief Financial Officer February 7, 1996 Report of Independent Auditors Board of Directors and Shareholders Eli Lilly and Company We have audited the accompanying consolidated balance sheets of Eli Lilly and Company and subsidiaries as of December 31, 1995 and 1994, and the related consolidated statements of income and cash flows for each of the three years in the period ended December 31, 1995. These financial statements are the responsibility of the company's management. Our responsibility is to express an opinion on these financial statements based on our audits. We conducted our audits in accordance with generally accepted auditing standards. Those standards require that we plan and perform the audit to obtain reasonable assurance about whether the financial statements are free of material misstatement. An audit includes examining, on a test basis, evidence supporting the amounts and disclosures in the financial statements. An audit also includes assessing the accounting principles used and significant estimates made by management, as well as evaluating the overall financial statement presentation. We believe that our audits provide a reasonable basis for our opinion. In our opinion, the financial statements referred to above present fairly, in all material respects, the consolidated financial position of Eli Lilly and Company and subsidiaries at December 31, 1995 and 1994, and the consolidated results of their operations and their cash flows for each of the three years in the period ended December 31, 1995, in conformity with generally accepted accounting principles. Indianapolis, Indiana February 5, 1996 Appendix to Exhibit 13 Graphs in Annual Report to Shareholders for the Year Ended December 31, 1995 Set forth below, converted to tabular format, are the graphs contained in the paper format of the portions of the Company's Annual Report to Shareholders that are contained in this Exhibit 13. Graph #1--Net Sales ($ millions) Year Amount ---- ------ 1985 $2,140.0 1986 1987 1988 1989 1990 1991 1992 1993 1994 1995 6,763.8 Strong worldwide volume growth in 1995 led to an 18 percent increase in net sales from continuing operations. Graph #2--Sales Outside the U.S. ($ millions) Year Amount ---- ------ 1986 $ 844.0 1987 1988 1989 1990 1991 1992 1993 1994 1995 2,950.9 Investments made in international markets since 1986 have resulted in an increase in sales outside the U.S. as a percent of total sales. Sales outside the U.S. increased from 34 percent in 1986 to nearly 44 percent in 1995. Graph #3--Sales by Therapeutic Class ($ millions; percentages represent change from 1994)) Percent Change Class Amount from 1994 ----- ------ -------------- Central Nervous System $2,266.4 +23% Anti-infectives 1,673.9 +2% Endocrine 1,179.1 +17% Gastrointestinal 548.4 +13% Animal Health 512.4 +11% Among Lilly's top five therapeutic classes, four experienced double-digit sales growth in 1995. Growth was led by the central- nervous-system class, which included increased Prozac sales of 24 percent. Graph #4--Research and Development Expenses ($ millions) Year Amount ---- ------ 1991 $590.5 1992 731.0 1993 755.0 1994 838.7 1995 1,042.3 The company's spending in support of global clinical trials increased 40 percent in 1995, driven by 19 compounds in Phase II or Phase III. Overall research and development spending increased 24 percent in 1995. Graph #5--Income from Continuing Operations ($ millions) Year Amount ---- ------ 1991 $1,166.1 1992 842.5 1993 464.8 1994 1,185.1 1995 1,306.6 Strong operating income growth substantially offset the negative impact of a full year's interest expense and goodwill amortization associated with the PCS acquisition. A lower effective tax rate also contributed to the growth of income from continuing operations. Operating income for 1992 and 1993 includes restructuring and special charges. See Note 3 to the consolidated financial statements. Graph #6--Capital Expenditures ($ millions) Year Amount ---- ------ 1991 $1,142.4 1992 912.9 1993 633.5 1994 576.5 1995 551.3 Capital expenditures during 1995 declined 4 percent from the 1994 level, their lowest level in five years. Graph #7--Dividends Paid per Share (dollars) Year Amount ---- ------ 1991 1.00 1992 1.10 1993 1.21 1994 1.25 1995 1.31 Dividends paid during 1995 were increased twice, totaling 4.8 percent. The increases continue to reflect the company's commitment to its shareholders. Nineteen ninety-five was the 28th consecutive year in which dividends increased.

    EXHIBIT 21  -  LIST OF SUBSIDIARIES AND AFFILIATES

    The following are the subsidiaries and affiliated corporations of
    the Company at December 31, 1995.

                                            State or Jurisdiction
                                              of Incorporation          %
                                               or Organization        Owned
                                                                

   ELI LILLY AND COMPANY                           Indiana

     Eli Lilly International Corporation           Indiana                  100
       Eli Lilly Int'l. Corp. - Branch:            England                  100
       Eli Lilly Iran, S.A.                        Iran                     100
       ELCO Insurance Company, Ltd.                Bermuda                  100

     Eli Lilly Interamerica, Inc.                  Indiana                  100
       Eli Lilly Interamerica, Inc. - Branch:      Argentina                100
       Eli Lilly Interamerica, Inc. - Branch:      Colombia                 100
       Eli Lilly Interamerica, Inc. - Branch:      Peru                     100
       Eli Lilly Interamerica, Inc. - Branch:      Dominican Republic       100
       Elanco Quimica Limitada                     Brazil                   100
        Eli Lilly do Brasil Limitada               Brazil                   100
          Darilor Sociedad Anonima                 Uruguay                  100
        Beimirco Sociedad Anonima                  Uruguay                  100
       Eli Lilly Interamerica Inc., y Compania     Chile                    100
             Limitada

     STC Pharmaceuticals, Inc.                     Indiana                  100
       Lilly Ranbaxy Pharmaceuticals L.L.C.        Indiana                  50
     Dista, Inc.                                   Indiana                  100
       Dista, Inc. - Branch:                       Colombia                 100

     Eli Lilly de Centro America, S.A.             Guatemala                100
       Eli Lilly de Centro America, S.A.-Branch:   Panama                   100
       Eli Lilly de Centro America, Sociedad       Costa Rica               100
              Anonima
       Eli Lilly de Centro America, S.A.-Branch:   Costa Rica               100

     Eli Lilly y Compania de Mexico, S.A. de C.V.  Mexico                   100
     Dista Mexicana, S.A. de C.V.                  Mexico                   100

     EPCO, Inc.                                    Indiana                  100
       DowElanco                                   Indiana                  40

     Hybritech Incorporated                        California               100
       Hybritech International, Inc.               California               100
        Hybritech Europe, S.A.                     Belgium                  100
       Hybritech Clinical, Inc.                    California               100
       Hybrigenetics Cancer Research, Inc.         California               100
       Hybritech G.m.b.H.                          Germany                  100
       Hybritech International Sales Corp.         California               100
     Eli Lilly Industries, Inc.                    Delaware                 100
     Eli Lilly and Company (Taiwan), Inc.          Taiwan                   100
     CBI Uniforms, Inc.                            Delaware                 50
     Control Diabetes Services, Inc.               Indiana                  100
     Integrated Disease Management, Inc.           Indiana                  100

   
   ELI LILLY AND COMPANY   (Cont'd)                Indiana

     PCS Holding Corporation (formerly McKesson    Delaware                 100
                              Delaware)
       Clinical Pharmaceuticals, Inc.              Delaware                 100
       Convenience Office Prescriptions            California               100
       Integrated Medical Systems, Inc.            Colorado                 100
        IMS-NET of Alabama, Inc.                   Alabama                  100
          Alabama Joint Venture                    Alabama                  51
        IMS-NET of Arizona, Inc.                   Arizona                  100
          Arizona Joint Venture, Limited           Arizona                  50
        IMS-NET of Illinois, Inc.                  Illinois                 100
          Illinois Medical Information Network,Inc. Illinois                68
        IMS-NET of California, Inc.                California               100
          IMS-NET of Sacramento, Inc.              California               100
        IMS-NET of Arkansas, Inc.                  Arkansas                 51
        IMS-NET of Central Florida, Inc.           Colorado                 51
        IMS-NET of Colorado, Inc.                  Colorado                 100
        IMS-NET of Kansas City, Inc.               Colorado                 100
        Indiana Medical Communication Network LLC  Colorado                 51
        Medical Communication Networks, Inc.       California               100
       Minnesota Medical Communication Network LLC Colorado                90
       LP Holding Corporation   (formerly          Maryland                 100
                                 McKesson Maryland)
        PCS Health Systems, Inc.                   Delaware                 100
          PCS of New York, Inc.                    New York                 100
          PCS Services, Inc.                       Delaware                 100

     ELCO Management Corporation                   Delaware                 100

       Eli Lilly Australia Pty. Limited            Australia                100
        Eli Lilly Australia Custodian Pty. Limited Bermuda                  100
        AZA Research Pty. Ltd.                     Australia                49
        Eli Lilly and Company (N.Z.) Limited       New Zealand              100
          Eli Lilly (NZ)Staff Benefits Custodian   New Zealand              100
                                       Limited
          Integrated Disease Management (NZ)       New Zealand              100
                                        Limited

       Eli Lilly Canada Inc.                       Canada                   100
       RxPlus                                      Canada                   100
       ELCO Dominicana, S.A.                       Dominican Republic       100
       ELCO International Sales Corporation        Virgin Islands-US        100
                                                            Possess.
       Eli Lilly Group Limited                     England                  100
        Lilly Industries Limited                   England                  100
          Dista Products Limited                   England                  100
          Eli Lilly and Company Limited            England                  100
          Lilly Research Centre Limited            England                  100
          Elanco Products Limited                  England                  100
          Creative Packaging Limited               England                  100
          Greenfield Pharmaceuticals Limited       England                  100
          Lilly Medical Instruments Limited        England                  100
        Eli Lilly Group Pension Trustees Limited   England                  100

       Lilly Deutschland GmbH                      Germany                  100
        Eli Lilly (Suisse) S.A. & Co.              Germany                  100
                      Beteiligungs-KG
          Beiersdorf-Lilly GmbH                    Germany                 74.8
          Lilly Medizintechnik GmbH                Germany                  100

       Eli Lilly & Co. (Ireland) Limited           Ireland                  100

       Eli Lilly Asia, Inc.                        Delaware                 100
        Eli Lilly Asia, Inc. - Branch              Hong Kong                100
        Eli Lilly Asia, Inc. - Branch              Korea                    100
        Eli Lilly Asia, Inc. - Branch              Thailand                 100
        Indian Branch                              India                    100
        China Branch                               China                    100
        Vietnam Branch                             Vietnam                  100

       Eli Lilly S.A.                              Switzerland              100
        Branch                                     Ireland                  100
        Eli Lilly Export S.A.                      Switzerland              100
          Puerto Rico - Branch                     Puerto Rico              100
          Egyptian Branch                          Egypt                    100
          Egyptian Branch                          Egypt                    100
          Russian Branch                           Russia                   100
        GEMS Services, S.A.                        Belgium                  100
          GEMS Services, S.A. - CC Branch          Belgium                  100
        T. P. Eli Lilly and Elanco D.O.O.          Yugoslavia               100
        Elanco Trustees Limited                    Ireland                  100
        DowElanco, B.V.                            Netherlands              40
        Eli Lilly (Suisse) S.A.                    Switzerland              100
          Iranian Branch                           Iran                     100
          Bulgarian Branch                         Bulgaria                 100
          Croatian Branch                          Croatia                  100
          Czech Republic Branch                    Czech Republic           100
          Estonian Branch                          Estonia                  100
          Hungarian Branch                         Hungary                  100
          Ivory Coast Branch                       Ivory Coast              100
          Kazakhstan Branch                        Kazakhstan               100
          Lebanon Branch                           Lebanon                  100
          Lithuanian Branch                        Lithuania                100
          Pakistani Branch                         Pakistan                 100
          Polish Branch                            Poland                   100
          Romanian Branch                          Romania                  100
          Slovakian Branch                         Slovakia                 100
          Slovenian Branch                         Slovenia                 100
          Ukraine Branch                           Ukraine                  100
          United Arab Emirates Branch              U.A.E.                   100
        Saudi Arabian Branch                       Saudi Arabia             100
        Eli Lilly MHC S.A.R.L.                     Switzerland              100
          Eli Lilly Mauritius                      Mauritius                99
            Ranbaxy Lilly Company                  India                    50
        Oldfields Financial Management S.A.        Switzerland              100
        Eli Lilly Suzhou Pharmaceutical Company    China                    90
                                        Limited
        Eli Lilly Nederland B.V.                   Netherlands              100
          Eli Lilly Ges.m.b.H.                     Austria                  100
          Lilly Development Centre S.A.            Belgium                  100
          Lilly Services S.A.                      Belgium                  100
          Lilly Clinical Operations S.A.           Belgium                  100
          Eli Lilly Benelux, S.A.                  Belgium                  100
          Eli Lilly CR s.r.o.                      Czech Republic           100
          Eli Lilly Denmark A/S                    Denmark                  100
          Eli Lilly Egypt                          Egypt                    75
          Alkan Pharma S.A.E.                      Egypt                    25
          OY Eli Lilly Finland Ab                  Finland                  100
          Lilly France S.A.                        France                   100
            Elsa France, S.A.                      France                   100
          Medco Ltd.                               Hungary                  50
          Lilly Hungaria KFT                       Hungary                  100

        Eli Lilly Nederland B.V. (Cont'd)          Netherlands              100
          Eli Lilly (Philippines), Incorporated    Philippines              100
          Eli Lilly Ranbaxy Limited                India                   50<5
          Dista Italia S.r.l.                      Italy                    100
          Eli Lilly Italia S.p.A.                  Italy                    100
          Eli Lilly Japan K.K.                     Japan                    100
          Daewoong Lilly Pharmaceutical Co., Ltd.  Korea                    50
          Eli Lilly Malaysia Sdn Bhd.              Malaysia                 100
          Damsen Trading Limited                   Malta                    51
          Eli Lilly Maroc S.a.r.l.                 Morocco                  100
          ELCO Production Services B.V.            Netherlands              100
          Eurobase B.V.                            Netherlands              55
          Eli Lilly Norge A.S.                     Norway                   100
          Eli Lilly-Gohar (Private) Limited        Pakistan                 30
          Eli Lilly Polska Sp. z.o.o. (Ltd.)       Poland                   100
          Lilly Grodzisk Sp. z.o.o.                Poland                  99.8
          Vitalia Pharma Sp. Z.o.o.                Poland                   51
          Dista-Produtos Quimicos &                Portugal                 100
                         Farmaceuticos,LDA
          Lilly-Farma, Produtos Farmaceuticos,Lda. Portugal                 100
          ELVA Joint Laboratory                    Russia                   50
          Pharmaserve - Lilly S.A.C.I.             Greece                  50.9
          Eli Lilly Asia Pacific Pte. Ltd.         Singapore                100
          Eli Lilly (S.A.) (Proprietary) Limited   South Africa             100
          Glaxo/Eli Lilly Partnership              South Africa             50
            The Medikredit Joint Venture           South Africa            37.6
                                 Partnership
                 Medikredit Pty. Ltd.              South Africa             80
          Elanco-Valquimica, S.A.                  Spain                   50<51
            Derly, S.A.                            Spain                   50<51
            Dista, S.A.                            Spain                   50<51
            Lilly, S.A.                            Spain                   50<51
          Geserco, S.A.                            Spain                   50<51
          Hybritech, S.A.                          Spain                   50<51
          Eli Lilly Sweden AB                      Sweden                   100
          Lilly Ilac Ticaret A.S.                  Turkey                   100
          Eli Lilly y Compania de Venezuela, S.A.  Venezuela                100
          Dista Products & Compania Venezuela      Venezuela                100


                    EXHIBIT 23.  CONSENT OF INDEPENDENT AUDITORS

            We consent to the incorporation by reference in this Annual
            Report (Form 10-K) of Eli Lilly and Company of our report
            dated February 5, 1996, included in the 1995 Annual Report
            to Shareholders of Eli Lilly and Company.

            We also consent to the incorporation by reference in
            Registration Statement Number 33-29482 on Form S-8 dated
            June 23, 1989, in Registration Statement Number 33-37341 on
            Form S-8 dated October 17, 1990, in Registration Statement
            Number 33-58466 on Form S-8 dated February 17 1993, in
            Registration Statement Number 33-50783 on Form S-8 dated
            October 27, 1993, and in Registration Statement Number 33-
            56141 dated October 24, 1994 of our report dated February 5,
            1996 with respect to the consolidated financial statements
            incorporated by reference, in the Annual Report (Form 10-K)
            of Eli Lilly and Company.


            ERNST & YOUNG LLP

            Indianapolis, Indiana

 

5 1,000 YEAR DEC-31-1995 DEC-31-1995 999,549 84,644 1,575,605 55,076 839,564 4,138,561 6,828,340 2,589,026 14,412,503 4,966,985 2,592,894 0 0 355,564 5,077,059 14,412,503 6,504,386 6,763,804 1,721,110 1,885,701 2,896,297 0 286,317 1,765,641 459,067 1,306,575 984,349 0 0 2,290,924 3.97 3.92 Note 2 - Amounts include research and development, selling, and general and . . . administrative expenses. Note 1 - The information called for is not given as the balances are not . . . individually significant.


      EXHIBIT 99.  REPORT TO HOLDERS OF ELI LILLY AND COMPANY
                   CONTINGENT PAYMENT OBLIGATION UNITS


         To Holders of Eli Lilly and Company Contingent Payment Obligation
         Units:


         In 1995,  sales  of Hybritech  Incorporated,  including  royalties,
         decreased 21 percent to $97.8 million.   Sales in 1994 were  $123.6
         million, down from $149.0 million in 1993.

         Product sales declined in 1995 due primarily to lower unit  volume.
         Sales of  the company's  largest selling  product, TandemR  PSA, a
         prostate cancer  test, were  down when  compared  to 1994,  due  to
         competition.

         Hybritech's gross profits declined 7  percent, to $54.9 million  in
         1995, compared with  $58.9 million and  $73.2 million  in 1994  and
         1993, respectively.  The gross-profit  decline in 1995 was  largely
         the result of lower sales.

         Beginning in  1993,  Hybritech  combined  certain  operations  with
         Pacific Biotech, Inc. (PBI), a wholly owned Lilly subsidiary.   PBI
         was sold  in  January 1995.    In addition,  Lilly  had  previously
         announced in 1994 that it intended to divest itself of its interest
         in Hybritech in a manner consistent with its obligations under  the
         Contingent Payment  Obligation Units  (CPUs).   The divestiture  of
         Hybritech to  Beckman Instruments,  Inc.,  which was  completed  on
         January 2, 1996, had no effect on the CPU calculation.

         Under the terms of the Contingent Payment Obligation Unit, payments
         are earned if the sum of 6 percent of sales and 20 percent of gross
         profits exceeds the annual deductible.   The annual deductible  was
         originally set in 1986 at $11 million and increases at a compounded
         rate of 35 percent  per year thereafter.   The deductibles  through
         1995 are as follows:

         (Dollars in millions)
         1991    1992    1993   1994   1995
         -----------------------------------

         $49.3  $66.6   $89.9  $121.4 $163.8

         In accordance with the formula, for 1995 the sum of 6 percent of
         sales and 20 percent of gross profits is approximately $16.8
         million.  Therefore, no payment was earned in 1995 (the final year
         of measurement under the CPUs), and the CPUs expire without
         payment.

         Tandem(R) (dual monoclonal sandwich assay kits, Hybritech)