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SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* Glycomed Incorporated (Name of Issuer) Common Stock (Title of Class of Securities) 380002 10 5 (CUSIP Number) Check the following box if a fee is being paid with the statement __. (A fee is not required only if the reporting person: (1) has a previous statement on file reporting beneficial ownership of more than five percent of the class of securities described in Item 1; and (2) has filed no amendment subsequent thereto reporting beneficial ownership of five percent or less of such class.) (See Rule 13d-7). *The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page. The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes). CUSIP No. 380002 10 5 (1) Name of Reporting Person: Eli Lilly and Company S.S. or I.R.S. Identification 35-0470950 No. of Above Person (2) Check the Appropriate Box (a) __ if a Member of a Group (b) __ Not Applicable (3) SEC Use Only (4) Citizenship or Place of Indiana Organization Number of Shares (5) Sole Voting 722,463 Beneficially Owned Power by Each Reporting (6) Shared Voting None Person With Power (7) Sole Dispositive 722,463 Power (8) Shared Disposi- None tive Power (9) Aggregate Amount Beneficially Owned by 722,463 Each Reporting Person (10) Check if the Aggregate Amount Not Applicable In Row (9) Excludes Certain Shares (11) Percent of Class Represented 5.73% at Dcember 31, 1993 by Amount in Row (9) (12) Type of Reporting Person CO Item 1(a). Name of Issuer Glycomed Incorporated Item 1(b). Address of Issuer's Principal Executive Offices 860 Atlantic Avenue Alameda, CA 94501 Item 2(a). Name of Person Filing Eli Lilly and Company Item 2(b). Address of Principal Business Office or, if None, Residence Lilly Corporate Center Indianapolis, IN 46285 Item 2(c). Citizenship Indiana Item 2(d). Title of Class of Securities Common Stock Item 2(e). CUSIP No. 380002 10 5 Item 3. Status of Filer Under Rules 13d-1(b) or 13d- 2(b) Not applicable Item 4. Ownership (a) Amount Beneficially Owned 722,463 (b) Percent of Class 5.73% as of December 31, 1993 (c) Voting and Dispositive Power Sole voting power 722,463 Shared voting power None Sole dispositive power 722,463 Shared dispositive power None Item 5. Ownership of Five Percent or Less of a Class Not applicable Item 6. Ownership of More Than Five Percent on Behalf of Another Person Not applicable Item 7. Identification and Classification of the Subsidiary which Acquired the Security Being Reported on by the Parent Holding Company Not applicable Item 8. Identification and Classification of Members of the Group Not applicable Item 9. Notice of Dissolution of Group Not applicable Item 10. Certification Not applicable SIGNATURE After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct. ELI LILLY AND COMPANY BY: s/James M. Cornelius James M. Cornelius, Vice President, Finance, and Chief Financial Officer Date: February 14, 1994