View Filing Data

Other comprehensive income (loss), net of tax (Note 12)

$ 1,327.2

$ (259.9)

$ 5,568.8

$ 957.5

87.0

^[1]

(671.2)

^[1]

139.7

(284.9)

Comprehensive income (loss)

1,414.2

(931.1)

5,708.5

672.6

Continuing Operations

Other comprehensive income (loss), net of tax (Note 12)

87.0

(511.0)

82.9

(215.4)

Discontinued Operations

Other comprehensive income (loss), net of tax (Note 12)

^[1]

$ 0.0

$ (160.2)

$ 56.8

$ (69.5)

[1]

⁽¹⁾For the six months ended June 30, 2019, other comprehensive income related to discontinued operations consisted of $45.8 million of accumulated other comprehensive income attributable to controlling interest and $11.0 million of accumulated other comprehensive income attributable to noncontrolling interest.

Beginning balance (in shares) at Dec. 31, 2017

The portion of profit or loss for the period, net of income taxes, which is attributable to the parent.

+ References + Details

Consolidated Condensed Statements of Comprehensive Income (Loss) (Unaudited) (Parenthetical) - USD ($) $ in Millions	Jun. 30, 2019	Mar. 31, 2019	Dec. 31, 2018	Jun. 30, 2018	Mar. 31, 2018	Dec. 31, 2017
Accumulated other comprehensive income	$ 2,857.3		$ 10,909.1
AOCI Attributable to Parent
Accumulated other comprehensive income	(5,600.5)	$ (5,687.5)	(5,729.2)	$ (6,108.7)	$ (5,437.5)	$ (5,718.6)
AOCI Attributable to Noncontrolling Interest
Accumulated other comprehensive income			$ 11.0			$ 23.7
Discontinued Operations \| AOCI Attributable to Parent
Accumulated other comprehensive income	45.8
Discontinued Operations \| AOCI Attributable to Noncontrolling Interest
Accumulated other comprehensive income	$ 11.0

Consolidated Condensed Balance Sheets - USD ($) $ in Millions	Jun. 30, 2019	Dec. 31, 2018
Current Assets
Cash and cash equivalents (Note 7)	$ 2,290.2	$ 7,320.7
Short-term investments (Note 7)	77.7	88.2
Accounts receivable, net of allowances of $23.7 (2019) and $24.1 (2018)	4,612.5	4,593.9
Other receivables	977.5	1,182.9
Inventories	3,181.1	3,098.1
Prepaid expenses and other	2,315.5	2,036.7
Current assets of discontinued operations (Note 5)	0.0	2,229.1
Total current assets	13,454.5	20,549.6
Investments (Note 7)	1,852.7	2,005.4
Goodwill	3,820.1	1,366.6
Other intangibles, net	6,586.6	1,068.0
Deferred tax assets	2,507.4	2,613.7
Sundry	2,052.1	1,824.9
Property and equipment, net of accumulated depreciation of $8,956.3 (2019) and $8,666.9 (2018)	7,847.5	7,996.1
Operating lease assets (Note 8)	545.5	0.0
Noncurrent assets of discontinued operations (Note 5)	0.0	6,484.1
Total assets	38,666.4	43,908.4
Current Liabilities
Short-term borrowings and current maturities of long-term debt	2,068.6	1,102.2
Accounts payable	1,198.9	1,207.1
Employee compensation	588.2	955.6
Sales rebates and discounts	4,993.7	4,849.5
Dividends payable	593.9	650.8
Income taxes payable	222.9	393.4
Other current liabilities	2,189.2	2,036.7
Current liabilities of discontinued operations (Note 5)	0.0	692.8
Total current liabilities	11,855.4	11,888.1
Other Liabilities
Long-term debt	13,717.6	9,196.4
Noncurrent operating lease liabilities (Note 8)	503.3	0.0
Accrued retirement benefits (Note 10)	2,723.4	2,802.2
Long-term income taxes payable	3,485.7	3,700.0
Deferred tax liabilities	2,380.9	1,312.7
Other noncurrent liabilities	1,142.8	1,357.6
Noncurrent liabilities of discontinued operations (Note 5)	0.0	2,742.3
Total other liabilities	23,953.7	21,111.2
Commitments and Contingencies (Note 11)
Eli Lilly and Company Shareholders’ Equity
Common stock	603.7	661.0
Additional paid-in capital	6,534.5	6,583.6
Retained earnings	4,318.1	11,395.9
Employee benefit trust	(3,013.2)	(3,013.2)
Accumulated other comprehensive loss (Note 12)	(5,600.5)	(5,729.2)
Cost of common stock in treasury	(62.1)	(69.4)
Total Eli Lilly and Company shareholders’ equity	2,780.5	9,828.7
Noncontrolling interests	76.8	1,080.4
Total equity	2,857.3	10,909.1
Total liabilities and equity	$ 38,666.4	$ 43,908.4

Consolidated Condensed Balance Sheets (Parenthetical) - USD ($) $ in Millions	Jun. 30, 2019	Dec. 31, 2018
Receivables, Net, Current [Abstract]
Allowances for doubtful accounts	$ 23.7	$ 24.1
Property and equipment, accumulated depreciation	$ 8,956.3	$ 8,666.9

Consolidated Condensed Statements of Equity (Unaudited) - USD ($)
shares in Thousands, $ in Millions

Total

Common Stock

Additional Paid-in Capital

Retained Earnings

Employee Benefit Trust

Accumulated Other Comprehensive Loss

Common Stock in Treasury

Noncontrolling Interests

1,100,672

664

Beginning balance at Dec. 31, 2017

$ 687.9

$ 5,817.8

$ 13,894.1

$ (3,013.2)

$ (5,718.6)

$ (75.8)

$ 75.7

Increase (Decrease) in Shareholders' Equity [Roll Forward]

957.5

4.6

(284.9)

(1,148.6)

(25,823)

$ (16.1)

(2,034.5)

$ 2,050.7

25,823

Issuance of stock under employee stock plans, net (in shares)

$ (2,050.7)

2,699

(60)

$ 1.7

(130.3)

$ 6.4

138.2

Ending balance (in shares) at Jun. 30, 2018

(5.6)

(14.7)

1,077,548

604

Ending balance at Jun. 30, 2018

$ 673.5

5,825.7

14,247.3

(3,013.2)

(6,108.7)

$ (69.4)

65.6

Beginning balance (in shares) at Mar. 31, 2018

1,089,234

604

Beginning balance at Mar. 31, 2018

$ 680.8

5,758.0

16,608.2

(3,013.2)

(5,437.5)

$ (69.3)

60.8

Increase (Decrease) in Shareholders' Equity [Roll Forward]

(259.9)

4.2

(671.2)

(1,148.6)

(11,735)

$ (7.3)

(943.3)

$ 950.7

11,735

Issuance of stock under employee stock plans, net (in shares)

$ (950.7)

(2.5)

$ (0.1)

70.2

Ending balance (in shares) at Jun. 30, 2018

(9.1)

0.6

1,077,548

604

Ending balance at Jun. 30, 2018

$ 673.5

5,825.7

14,247.3

(3,013.2)

(6,108.7)

$ (69.4)

65.6

Beginning balance (in shares) at Dec. 31, 2018

1,057,639

604

Beginning balance at Dec. 31, 2018

$ 10,909.1

$ 661.0

6,583.6

11,395.9

(3,013.2)

(5,729.2)

$ (69.4)

1,080.4

Increase (Decrease) in Shareholders' Equity [Roll Forward]

5,568.8

21.1

128.7

11.0

(1,178.1)

(94,627)

$ (59.1)

(11,468.5)

$ 11,527.5

^[1]

(29,626)

Issuance of stock under employee stock plans, net (in shares)

^[1]

$ (3,500.0)

2,945

(63)

$ 1.8

(204.4)

$ 7.3

Acquisition of common stock in exchange offer (in shares)

155.3

65,001

Acquisition of common stock in exchange offer

$ (8,027.5)

Deconsolidation of Elanco

(1,028.9)

Ending balance (in shares) at Jun. 30, 2019

(6.8)

965,957

541

Ending balance at Jun. 30, 2019

2,857.3

$ 603.7

6,534.5

4,318.1

(3,013.2)

(5,600.5)

$ (62.1)

76.8

Beginning balance (in shares) at Mar. 31, 2019

971,363

541

Beginning balance at Mar. 31, 2019

$ 607.1

5,756.6

4,879.4

(3,013.2)

(5,687.5)

$ (62.1)

84.7

Increase (Decrease) in Shareholders' Equity [Roll Forward]

1,327.2

(1.1)

87.0

(1,178.1)

(5,430)

$ (3.4)

(696.6)

$ 700.0

^[2]

700,000

5,430

Issuance of stock under employee stock plans, net (in shares)

^[2]

$ (700.0)

$ (1.6)

79.5

Ending balance (in shares) at Jun. 30, 2019

(13.8)

(6.8)

965,957

541

Ending balance at Jun. 30, 2019

$ 2,857.3

$ 603.7

$ 6,534.5

$ 4,318.1

$ (3,013.2)

$ (5,600.5)

$ (62.1)

$ 76.8

[1]	As of June 30, 2019, there was $2.40 billion remaining under our $8.00 billion share repurchase program authorized in June 2018.
[2]	As of June 30, 2019, there was $2.40 billion remaining under our $8.00 billion share repurchase program authorized in June 2018.

Consolidated Condensed Statements of Equity (Unaudited) (Parenthetical) - USD ($) $ in Millions	3 Months Ended		6 Months Ended
	Jun. 30, 2019	Jun. 30, 2018	Jun. 30, 2019	Jun. 30, 2018
Statement of Stockholders' Equity [Abstract]
Cash dividends declared per share (in dollars per share)	$ 1.29	$ 1.13	$ 1.29	$ 1.13
Remaining authorized repurchase amount	$ 2,400		$ 2,400
Stock repurchase program, authorized amount		$ 8,000		$ 8,000

Consolidated Condensed Statements of Cash Flows (Unaudited) - USD ($) $ in Millions	6 Months Ended
	Jun. 30, 2019	Jun. 30, 2018
Cash Flows from Operating Activities
Net income	$ 5,568.8	$ 957.5
Adjustments to Reconcile Net Income to Cash Flows from Operating Activities:
Gain related to disposition of Elanco (Note 5)	(3,680.5)	0.0
Depreciation and amortization	603.9	848.0
Change in deferred income taxes	(11.3)	134.8
Stock-based compensation expense	155.3	138.2
Acquired in-process research and development (Note 3)	161.9	1,624.5
Other changes in operating assets and liabilities, net of acquisitions and divestitures	(1,516.4)	(1,932.1)
Other non-cash operating activities, net	81.1	183.1
Net Cash Provided by Operating Activities	1,362.8	1,954.0
Cash Flows from Investing Activities
Net purchases of property and equipment	(444.0)	(546.5)
Proceeds from sales and maturities of short-term investments	89.4	2,496.7
Purchases of short-term investments	(34.1)	(112.2)
Proceeds from sales of noncurrent investments	416.4	3,395.1
Purchases of noncurrent investments	(146.6)	(676.5)
Cash paid for acquisitions, net of cash acquired (Note 3)	(6,917.7)	0.0
Purchase of in-process research and development	(241.9)	(1,548.2)
Other investing activities, net	(339.2)	(45.3)
Net Cash Provided by (Used for) Investing Activities	(7,617.7)	2,963.1
Cash Flows from Financing Activities
Dividends paid	(1,235.2)	(1,166.6)
Net change in short-term borrowings	1,564.3	(248.7)
Proceeds from issuance of long-term debt	4,448.3	0.0
Repayments of long-term debt	(600.2)	(1,001.5)
Purchases of common stock	(3,500.0)	(2,050.7)
Other financing activities, net	(195.2)	(230.4)
Net Cash Provided by (Used for) Financing Activities	482.0	(4,697.9)
Effect of exchange rate changes on cash and cash equivalents	64.9	61.9
Net increase (decrease) in cash and cash equivalents	(5,708.0)	281.1
Cash and cash equivalents at January 1 (includes $677.5 (2019) and $324.4 (2018) of discontinued operations)	$ 7,998.2	6,536.2
Cash and Cash Equivalents at June 30 (includes $322.1 (2018) of discontinued operations)		$ 6,817.3

Consolidated Condensed Statements of Cash Flows (Unaudited) (Parenthetical) - USD ($) $ in Millions	Dec. 31, 2018	Jun. 30, 2018	Dec. 31, 2017
Statement of Cash Flows [Abstract]
Discontinued operations cash	$ 667.5	$ 322.1	$ 324.4

Basis of Presentation and Implementation of New Financial Accounting Standards	6 Months Ended
	Jun. 30, 2019
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Basis of Presentation and Implementation of New Financial Accounting Standards	Basis of Presentation and Implementation of New Financial Accounting Standards On March 11, 2019, we completed the disposition of our remaining 80.2 percent ownership of Elanco Animal Health (Elanco) common stock through a tax-free exchange offer. As a result, Elanco has been presented as discontinued operations in our consolidated condensed financial statements for all periods presented. We have prepared the accompanying unaudited consolidated condensed financial statements in accordance with the requirements of Form 10-Q and, therefore, they do not include all information and footnotes necessary for a fair presentation of financial position, results of operations, and cash flows in conformity with accounting principles generally accepted in the United States (GAAP). In our opinion, the financial statements reflect all adjustments (including those that are normal and recurring) that are necessary for a fair presentation of the results of operations for the periods shown. In preparing financial statements in conformity with GAAP, we must make estimates and assumptions that affect the reported amounts of assets, liabilities, revenue, expenses, and related disclosures at the date of the financial statements and during the reporting period. Actual results could differ from those estimates. The information included in this Quarterly Report on Form 10-Q should be read in conjunction with our consolidated financial statements and accompanying notes included in our Annual Report on Form 10-K for the year ended December 31, 2018. We issue our financial statements by filing them with the Securities and Exchange Commission and have evaluated subsequent events up to the time of the filing. All per-share amounts, unless otherwise noted in the footnotes, are presented on a diluted basis, that is, based on the weighted-average number of outstanding common shares plus the effect of incremental shares from our stock-based compensation programs. Following the completion of the disposition of Elanco, we now operate as a single operating segment engaged in the discovery, development, manufacturing, marketing, and sales of pharmaceutical products worldwide. A global research and development organization and a supply chain organization are responsible for the discovery, development, manufacturing, and supply of our products. Regional commercial organizations market, distribute, and sell the products. The business is also supported by global corporate staff functions. Our determination that we operate as a single segment is consistent with the financial information regularly reviewed by the chief operating decision maker for purposes of evaluating performance, allocating resources, setting incentive compensation targets, and planning and forecasting for future periods. On January 1, 2019 we adopted Accounting Standards Update 2016-02, Leases, using the modified retrospective approach, applied at the beginning of the period of adoption, and we elected the package of transitional practical expedients. The adoption of this standard resulted in recording of operating lease assets of approximately $530 million, which included reclassifying approximately $65 million of deferred rent and lease incentives, net of prepaid rent, as a component of the operating lease assets as of January 1, 2019. The adoption also resulted in recording operating lease liabilities of approximately $595 million as of January 1, 2019. Our accounting for finance leases remained substantially unchanged. The standard did not have an impact on our consolidated condensed statements of operations.

Revenue

6 Months Ended

Jun. 30, 2019

Revenue from Contract with Customer [Abstract]

Revenue

The following table summarizes our revenue recognized in our consolidated condensed statements of operations:



	Three Months Ended June 30,				Six Months Ended June 30,
	2019		2018		2019		2018
Net product revenue	$	5,168.7	$	5,129.4	$	9,861.0	$	9,735.3
Collaboration and other revenue ⁽¹⁾	468.0		455.6		867.9		813.5
Revenue	$	5,636.7	$	5,585.0	$	10,728.9	$	10,548.8

⁽¹⁾Collaboration and other revenue associated with prior period transfers of intellectual property was $59.6 million and $95.1 million during the three and six months ended June 30, 2019, respectively, and $133.6 million and $183.7 million during the three and six months ended June 30, 2018, respectively.

We recognize revenue primarily from two different types of contracts, product sales to customers (net product revenue) and collaborations and other arrangements. Revenue recognized from collaborations and other arrangements will include our share of profits from the collaboration, as well as royalties, upfront and milestone payments we receive under these types of contracts. See Note 4 for additional information related to our collaborations and other arrangements. Collaboration and other revenue disclosed above includes the revenue from the Trajenta^® and Jardiance^® families of products resulting from our collaboration with Boehringer Ingelheim discussed in Note 4. Substantially all of the remainder of collaboration and other revenue is related to contracts accounted for as contracts with customers.

Disaggregation of Revenue

The following table summarizes revenue by product:



	Three Months Ended June 30,
	2019						2018
	United States (U.S.) ⁽¹⁾		Outside U.S.		Total		U.S. ⁽¹⁾		Outside U.S.		Total
Revenue—to unaffiliated customers:
Endocrinology:
Trulicity^®	$	792.1	$	236.4	$	1,028.5	$	612.4	$	167.4	$	779.8
Humalog^{® (2)}	396.1		281.5		677.6		464.5		305.2		769.8
Forteo^®	172.8		188.0		360.8		225.1		209.4		434.5
Humulin^®	220.1		102.6		322.6		238.8		107.2		346.0
Basaglar^®	232.2		58.6		290.7		156.5		45.3		201.8
Jardiance ⁽³⁾	142.6		89.3		231.9		85.6		61.6		147.2
Trajenta ⁽⁴⁾	64.5		89.5		153.9		56.8		84.9		141.7
Other Endocrinology	81.6		59.3		141.2		61.5		72.8		134.1
Total Endocrinology	2,102.0		1,105.2		3,207.2		1,901.2		1,053.8		2,954.9

Oncology:
Alimta^®	341.7		236.1		577.8		281.3		274.6		555.9
Cyramza^®	89.8		152.0		241.8		75.4		143.3		218.8
Erbitux^®	136.9		22.4		159.3		140.0		26.4		166.4
Verzenio^®	105.2		28.7		133.9		57.7		—		57.7
Other Oncology	16.2		68.2		84.4		56.7		54.7		111.3
Total Oncology	689.8		507.4		1,197.2		611.1		499.0		1,110.1

Neuroscience:
Cymbalta^®	18.1		169.0		187.2		12.6		169.4		181.9
Zyprexa^®	9.3		95.1		104.3		11.8		116.2		128.0
Strattera^®	21.2		61.4		82.6		16.9		97.3		114.2
Emgality^®	33.8		0.5		34.3		—		—		—
Other Neuroscience	22.0		22.3		44.3		24.3		22.4		46.9
Total Neuroscience	104.4		348.3		452.7		65.6		405.3		471.0

Immunology:
Taltz^®	268.1		85.7		353.8		173.6		46.5		220.1
Olumiant^®	10.7		91.7		102.4		1.7		42.9		44.7
Total Immunology	278.8		177.3		456.1		175.3		89.4		264.7

Other:
Cialis^®	35.1		165.1		200.2		345.7		193.0		538.7
Other	42.4		80.8		123.3		143.4		102.2		245.6
Total Other	77.5		245.9		323.5		489.1		295.2		784.3
Revenue	$	3,252.5	$	2,384.2	$	5,636.7	$	3,242.3	$	2,342.7	$	5,585.0

Numbers may not add due to rounding.

⁽¹⁾U.S. revenue includes revenue in Puerto Rico.

⁽²⁾Humalog revenue includes Insulin Lispro.

⁽³⁾Jardiance revenue includes Glyxambi^®and Synjardy^®.

⁽⁴⁾Trajenta revenue includes Jentadueto^®.



	Six Months Ended June 30,
	2019						2018
	U.S. ⁽¹⁾		Outside U.S.		Total		U.S. ⁽¹⁾		Outside U.S.		Total
Revenue—to unaffiliated customers:
Endocrinology:
Trulicity	$	1,457.7	$	450.6	$	1,908.3	$	1,140.6	$	317.5	$	1,458.1
Humalog ⁽²⁾	844.8		563.7		1,408.4		968.7		592.8		1,561.5
Forteo	298.7		375.0		673.7		347.2		400.5		747.8
Humulin	421.3		199.0		620.3		460.4		211.5		671.9
Basaglar	430.3		111.8		542.1		283.2		84.6		367.8
Jardiance ⁽³⁾	267.8		167.7		435.5		180.6		117.6		298.2
Trajenta ⁽⁴⁾	111.8		174.0		285.9		110.9		171.9		282.8
Other Endocrinology	143.5		119.6		263.1		125.4		140.2		265.6
Total Endocrinology	3,975.9		2,161.4		6,137.3		3,617.0		2,036.6		5,653.7

Oncology:
Alimta	623.5		453.5		1,076.9		526.7		528.9		1,055.5
Cyramza	164.9		275.2		440.0		143.7		258.7		402.4
Erbitux	250.3		27.5		277.7		261.3		54.7		316.1
Verzenio	198.7		44.6		243.3		87.4		—		87.4
Other Oncology	46.3		125.5		172.1		102.3		103.0		205.3
Total Oncology	1,283.7		926.3		2,210.0		1,121.4		945.3		2,066.7

Neuroscience:
Cymbalta	28.4		322.9		351.3		24.8		326.7		351.5
Zyprexa	18.6		193.0		211.5		20.6		230.0		250.6
Strattera	22.7		126.1		148.8		63.9		181.0		244.9
Emgality	46.0		2.6		48.5		—		—		—
Other Neuroscience	39.8		45.7		85.8		48.5		48.2		96.7
Total Neuroscience	155.5		690.3		845.9		157.8		785.9		943.7

Immunology:
Taltz	449.0		157.4		606.3		284.7		81.8		366.5
Olumiant	17.1		167.4		184.5		1.7		75.2		76.9
Total Immunology	466.0		324.8		790.8		286.5		157.0		443.4

Other:
Cialis	178.4		330.0		508.4		659.1		375.0		1,034.1
Other	83.8		152.8		236.5		196.1		211.1		407.2
Total Other	262.2		482.9		744.9		855.2		586.1		1,441.3
Revenue	$	6,143.3	$	4,585.6	$	10,728.9	$	6,037.9	$	4,510.9	$	10,548.8

Numbers may not add due to rounding.

⁽¹⁾U.S. revenue includes revenue in Puerto Rico.

⁽²⁾Humalog revenue includes Insulin Lispro.

⁽³⁾Jardiance revenue includes Glyxambiand Synjardy.

⁽⁴⁾Trajenta revenue includes Jentadueto.

The following table summarizes revenue by geographical area:



	Three Months Ended June 30,				Six Months Ended June 30,
	2019		2018		2019		2018
Revenue—to unaffiliated customers ⁽¹⁾:
United States ⁽²⁾	$	3,252.5	$	3,242.3	$	6,143.3	$	6,037.9
Europe	928.2		941.0		1,828.5		1,834.8
Japan	653.2		640.4		1,196.9		1,177.2
Other foreign countries	802.8		761.2		1,560.2		1,498.8
Revenue	$	5,636.7	$	5,585.0	$	10,728.9	$	10,548.8

Numbers may not add due to rounding.

⁽¹⁾Revenue is attributed to the countries based on the location of the customer.

⁽²⁾U.S. revenue includes revenue in Puerto Rico.

Adjustments to Revenue

Adjustments to revenue recognized as a result of changes in estimates for our most significant U.S. sales returns, rebates, and discounts liability balances for products shipped in previous periods were approximately 4 percent and 3 percent of U.S. revenue during the three and six months ended June 30, 2019, respectively, and approximately 1 percent and 2 percent of U.S. revenue during the three and six months ended June 30, 2018, respectively.

Contract Liabilities

Our contract liabilities result from arrangements where we have received payment in advance of performance under the contract and do not include sales returns, rebates, and discounts. Changes in contract liabilities are generally due to either receipt of additional advance payments or our performance under the contract.

The following table summarizes contract liability balances:



	June 30, 2019		December 31, 2018
Contract liabilities	$	277.6	$	294.9

Revenue recognized from contract liabilities during the three and six months ended June 30, 2019 and 2018 was not material. Revenue expected to be recognized in the future from contract liabilities as the related performance obligations are satisfied is not expected to be material in any one year.

Acquisitions and Divestiture

6 Months Ended

Jun. 30, 2019

Business Combinations [Abstract]

Acquisitions and Divestiture

In February 2019, we completed the acquisition of Loxo Oncology, Inc. (Loxo). This transaction, as further discussed in this note below in Acquisition of a Business, was accounted for as a business combination under the acquisition method of accounting. Under this method, the assets acquired and liabilities assumed were recorded at their respective fair values as of the acquisition date in our consolidated condensed financial statements. The determination of estimated fair value required management to make significant estimates and assumptions. The excess of the purchase price over the fair value of the acquired net assets, where applicable, has been recorded as goodwill. The results of operations of this acquisition have been included in our consolidated condensed financial statements from the date of acquisition.

Additionally, we acquired assets in development which are further discussed in this note below in Asset Acquisitions. Upon acquisition, the acquired in-process research and development (IPR&D) charges related to these products were immediately expensed because the products had no alternative future use. We incurred acquired IPR&D charges of $25.0 million and $161.9 million for the three and six months ended June 30, 2019, respectively, and $1.62 billion for the three and six months ended June 30, 2018.

Acquisition of a Business

Loxo Acquisition

Overview of Transaction

In February 2019, we acquired all shares of Loxo for a purchase price $6.92 billion, net of cash acquired. The accelerated vesting of Loxo employee equity awards was recognized as transaction expense included in asset impairment, restructuring, and other special charges during the six months ended June 30, 2019.

Under the terms of the agreement, we acquired a pipeline of investigational medicines, including LOXO-292, an oral RET inhibitor that has been granted Breakthrough Therapy designation by the U.S. Food and Drug Administration, and LOXO-305, an oral BTK inhibitor.

Assets Acquired and Liabilities Assumed

Our access to Loxo information was limited prior to the acquisition. As a consequence, we are in the process of determining fair values and tax bases of a significant portion of the assets acquired and liabilities assumed, including the identification and valuation of intangible assets, accrued expenses, and tax exposures. The final determination of these amounts will be completed as soon as possible but no later than one year from the acquisition date. The final determination may result in asset and liability fair values and tax bases that differ from the preliminary estimates and require changes to the preliminary amounts recognized.

The following table summarizes the preliminary amounts recognized for assets acquired and liabilities assumed as of the acquisition date:



Estimated Fair Value at February 15, 2019
Acquired in-process research and development	$	4,670.0
Definite-lived intangibles ⁽¹⁾	960.0
Deferred income taxes	(1,134.3		)
Other assets and liabilities - net	(31.4		)
Total identifiable net assets	4,464.3
Goodwill ⁽²⁾	2,453.4
Total consideration transferred - net of cash acquired	$	6,917.7

⁽¹⁾Contract-based intangibles, which are being amortized to cost of sales on a straight-line basis over their estimated useful lives, were expected to have a weighted average useful life of approximately 12 years from the acquisition date.

⁽²⁾The goodwill recognized from this acquisition is attributable primarily to future unidentified projects and products and the assembled workforce for Loxo and is not deductible for tax purposes.

Asset Acquisitions

The following table summarizes our asset acquisitions during the six months ended June 30, 2019 and June 30, 2018.



Counterparty	Compound(s) or Therapy	Acquisition Month	Phase of Development ⁽¹⁾	Acquired IPR&D Expense
AC Immune SA	Tau aggregation inhibitor small molecules for the potential treatment of Alzheimer's disease and other neurodegenerative diseases	January 2019	Pre-clinical	$	96.9
ImmuNext, Inc.	Novel immunometabolism target	March 2019	Pre-clinical	40.0
Avidity Biosciences, Inc.	Potential new medicines in immunology and other select indications	April 2019	Pre-clinical	25.0

Sigilon Therapeutics	Encapsulated cell therapies for the potential treatment of type 1 diabetes	April 2018	Pre-clinical	66.9
AurKa Pharma, Inc.	AK-01, an Aurora kinase A inhibitor	June 2018	Phase I	81.8
ARMO Biosciences, Inc.	Cancer therapy - pegilodecakin	June 2018	Phase III	1,475.8

⁽¹⁾The phase of development presented is as of the date of the arrangement and represents the phase of development of the most advanced asset acquired, where applicable.

In connection with these arrangements, our partners may be entitled to future royalties and/or commercial milestones based on sales should products be approved for commercialization and/or milestones based on the successful progress of compounds through the development process.

Divestiture

In April 2019, we announced an agreement to sell the rights in China for two legacy antibiotic medicines, as well as a manufacturing facility in Suzhou, China to Eddingpharm, a China-based specialty pharmaceutical company. Under terms of the agreement, we received a deposit of $75.0 million, and will receive a payment of $300.0 million upon successful closing of the transaction. The transaction is subject to customary closing conditions and regulatory approval.

Subsequent Event

In July 2019, we entered into a license agreement with Centrexion Therapeutics Corporation for CNTX-0290, a novel, small molecule somatostatin receptor type 4 agonist. CNTX-0290 is being studied in phase I clinical testing as a potential non-opioid treatment for chronic pain conditions. Under the terms of the agreement, we acquired worldwide rights for CNTX-0290 for an upfront payment of $47.5 million and success-based milestones and royalties. As a result of the transaction, we will record an acquired IPR&D charge of $47.5 million in the third quarter of 2019.

Collaborations and Other Arrangements

6 Months Ended

Jun. 30, 2019

Organization, Consolidation and Presentation of Financial Statements [Abstract]

Collaborations and Other Arrangements

We often enter into collaborative and other similar arrangements to develop and commercialize drug candidates. Collaborative activities may include research and development, marketing and selling (including promotional activities and physician detailing), manufacturing, and distribution. These arrangements often require milestone and royalty or profit-share payments, contingent upon the occurrence of certain future events linked to the success of the asset in development, as well as expense reimbursements or payments to the collaboration partner. See Note 2 for amounts of collaboration and other revenue recognized from these types of arrangements.

Operating expenses for costs incurred pursuant to these arrangements are reported in their respective expense line item, net of any payments due to or reimbursements due from our collaboration partners, with such reimbursements being recognized at the time the party becomes obligated to pay. Each collaboration is unique in nature, and our more significant arrangements are discussed below.

Boehringer Ingelheim Diabetes Collaboration

We and Boehringer Ingelheim have a global agreement to jointly develop and commercialize a portfolio of diabetes compounds. Currently included in the collaboration are Boehringer Ingelheim’s oral diabetes products: Trajenta, Jentadueto, Jardiance, Glyxambi, and Synjardy, as well as our basal insulin, Basaglar.

The table below summarizes significant milestones (deferred) capitalized for the compounds included in this collaboration:



Product Family	Milestones (Deferred) Capitalized ⁽¹⁾
Trajenta ⁽²⁾	$	446.4
Jardiance ⁽³⁾	289.0
Basaglar	(250.0		)

⁽¹⁾In connection with the regulatory approvals of Basaglar in the U.S., Europe, and Japan, milestone payments received were recorded as contract liabilities and are being amortized through the term of the collaboration (2029) to collaboration and other revenue. In connection with the regulatory approvals of Trajenta and Jardiance, milestone payments made were capitalized as intangible assets and are being amortized to cost of sales through the term of the collaboration. This represents the cumulative amounts that have been (deferred) or capitalized from the start of this collaboration through the end of the reporting period.

⁽²⁾Jentadueto is included in the Trajenta product family. The collaboration agreement with Boehringer Ingelheim for Trajenta ends upon expiration of the compound patent and any supplementary protection certificates or extensions thereto.

⁽³⁾Glyxambi and Synjardyare included in the Jardiance product family. The collaboration agreement with Boehringer Ingelheim for Jardiance ends upon expiration of the compound patent and any supplementary protection certificates or extensions thereto.

In the most significant markets, we and Boehringer Ingelheim share equally the ongoing development costs, commercialization costs, and agreed upon gross margin for any product resulting from the collaboration. We record our portion of the gross margin associated with Boehringer Ingelheim's products as collaboration and other revenue. We record our sales of Basaglar to third parties as net product revenue with the payments made to Boehringer Ingelheim for its portion of the gross margin recorded as cost of sales. For all compounds under this collaboration, we record our portion of the development and commercialization costs as research and development expense and marketing, selling, and administrative expense, respectively. Each company is entitled to potential performance payments depending on the sales of the molecules it contributes to the collaboration. These performance payments result in the owner of the molecule retaining a greater share of the agreed upon gross margin of that product. Subject to achieving these thresholds, in a given period, our reported revenue for Trajenta and Jardiance may be reduced by any performance payments we make related to these products. Similarly, performance payments we may receive related to Basaglar effectively reduce Boehringer Ingelheim's share of the gross margin, which reduces our cost of sales.

The following table summarizes our net product revenue recognized with respect to Basaglar and collaboration and other revenue recognized with respect to the Trajenta and Jardiance families of products:



	Three Months Ended June 30,				Six Months Ended June 30,
	2019		2018		2019		2018
Basaglar	$	290.7	$	201.8	$	542.1	$	367.8
Jardiance	231.9		147.2		435.5		298.2
Trajenta	153.9		141.7		285.9		282.8

Olumiant

We have a worldwide license and collaboration agreement with Incyte Corporation (Incyte), which provides us the development and commercialization rights to its Janus tyrosine kinase (JAK) inhibitor compound, now known as Olumiant, and certain follow-on compounds, for the treatment of inflammatory and autoimmune diseases. Incyte has the right to receive tiered, double-digit royalty payments on future global sales with rates ranging up to 20 percent. The agreement calls for payments by us to Incyte associated with certain development, success-based regulatory, and sales-based milestones.

The following table summarizes our significant milestones achieved:



Year	Event	Classification	Amount
2018	Regulatory approval in the U.S.	Intangible asset	$	100.0
2018	Began Phase III testing for systemic lupus erythematosus (SLE)	R&D Expense	20.0
2017	Regulatory approval in Europe	Intangible asset	65.0
	Regulatory approval in Japan	Intangible asset	15.0
	Began Phase III testing for atopic dermatitis	R&D expense	30.0
2016	Regulatory submissions in the U.S. and Europe	R&D expense	55.0

As of June 30, 2019, Incyte is eligible to receive up to $130.0 million of additional payments from us contingent upon certain development and success-based regulatory milestones. Incyte is also eligible to receive up to $150.0 million of potential sales-based milestones.

The agreement provided Incyte with options to co-develop these compounds on an indication-by-indication basis by funding 30 percent of the associated development costs from the initiation of a Phase IIb trial through regulatory approval in exchange for increased tiered royalties ranging up to percentages in the high twenties. Incyte previously exercised its option to co-develop Olumiant in rheumatoid arthritis, atopic dermatitis, alopecia areata, and SLE. Incyte opted-out of co-development of all indications as of January 1, 2019. As a result, we will solely fund all future development and pay a lower royalty rate to Incyte on future sales.

The following table summarizes our net product revenue recognized with respect to Olumiant:



	Three Months Ended June 30,				Six Months Ended June 30,
	2019		2018		2019		2018
Olumiant	$	102.4	$	44.7	$	184.5	$	76.9

Tanezumab

We have a collaboration agreement with Pfizer Inc. (Pfizer) to jointly develop and globally commercialize tanezumab for the treatment of osteoarthritis pain, chronic low back pain, and cancer pain. Under the agreement, the companies share equally the ongoing development costs and, if successful, in gross margins and certain commercialization expenses. As of June 30, 2019, Pfizer is eligible to receive up to $350.0 million in success-based regulatory milestones and up to $1.23 billion in a series of sales-based milestones, contingent upon the commercial success of tanezumab.

Discontinued Operations

6 Months Ended

Jun. 30, 2019

Discontinued Operations and Disposal Groups [Abstract]

Discontinued Operations

On March 11, 2019, we completed the disposition of our remaining 80.2 percent ownership of Elanco common stock through a tax-free exchange offer. As a result, we have included the financial results of Elanco through March 11, 2019 and have presented Elanco as discontinued operations in our consolidated condensed financial statements for all periods presented.



	Three Months Ended June 30,					Six Months Ended June 30,
	2019		2018			2019		2018
Revenue	$	—	$	770.2		$	580.0	$	1,506.4
Net income (loss) from discontinued operations	—		(28.3		)	3,680.5		21.9

The operating results of Elanco were reported as net income (loss) from discontinued operations in the consolidated condensed statements of operations through March 11, 2019, the date of disposition, and were not material for all periods presented. For the six months ended June 30, 2019, we recognized a gain related to the disposition of approximately $3.7 billion, which was also recorded in net income (loss) from discontinued operations in the consolidated condensed statement of operations.

In the consolidated condensed balance sheet as of December 31, 2018, the assets and liabilities associated with Elanco are classified as assets of discontinued operations and liabilities of discontinued operations, as appropriate. The following table presents the major classes of assets and liabilities from discontinued operations:



	December 31, 2018
Inventories	$	1,013.7
Other current assets	1,215.4
Current assets of discontinued operations	$	2,229.1

Goodwill	$	2,980.9
Other intangibles, net	2,453.0
Property and equipment, net	923.4
Other assets	126.8
Noncurrent assets of discontinued operations	$	6,484.1

Current liabilities of discontinued operations	$	692.8

Long-term debt	$	2,443.3
Other liabilities	299.0
Noncurrent liabilities of discontinued operations	$	2,742.3

The gain related to the disposition of Elanco in the consolidated condensed statement of cash flows includes the operating results of Elanco, which were not material. The net cash flows of our discontinued operations for operating and investing activities were not material for all periods presented.

We entered into a transitional services agreement (TSA) with Elanco that is designed to facilitate the orderly transfer of various services to Elanco. The TSA relates primarily to administrative services, which are generally to be provided over 24 months. This agreement is not material and does not confer upon us the ability to influence the operating and/or financial policies of Elanco subsequent to March 11, 2019, the full disposition date.

Asset Impairment, Restructuring, and Other Special Charges

6 Months Ended

Jun. 30, 2019

Restructuring and Related Activities [Abstract]

Asset Impairment, Restructuring, and Other Special Charges

The components of the charges included in asset impairment, restructuring, and other special charges in our consolidated condensed statements of operations are described below.



	Three Months Ended June 30,					Six Months Ended June 30,
	2019		2018			2019			2018
Severance	$	—	$	(24.6	)	$	(3.6	)	$	(17.3	)
Asset impairment and other special charges	—		(0.9		)	427.5			48.6
Total asset impairment, restructuring, and other special charges	$	—	$	(25.5	)	$	423.9		$	31.3

Our severance charges recognized in the second half of 2017 as part of planned restructuring activities were based upon estimates for the number of employees that either lost or were going to lose their then current roles and would ultimately leave the company. During the second quarter of 2018, we determined that more displaced employees than expected were able to find other roles within the company, resulting in a reduction in the actual severance costs incurred.

Asset impairment and other special charges recognized during the six months ended June 30, 2019 consisted of $400.7 million related to the acquisition of Loxo, substantially all of which is associated with the accelerated vesting of Loxo employee equity awards.

Financial Instruments

6 Months Ended

Jun. 30, 2019

Fair Value Disclosures [Abstract]

Financial Instruments

Financial instruments that potentially subject us to credit risk consist principally of trade receivables and interest-bearing investments. Wholesale distributors of life-science products account for a substantial portion of our trade receivables; collateral is generally not required. We seek to mitigate the risk associated with this concentration through our ongoing credit-review procedures and insurance. A large portion of our cash is held by a few major financial institutions. We monitor our exposures with these institutions and do not expect any of these institutions to fail to meet their obligations. Major financial institutions represent the largest component of our investments in corporate debt securities. In accordance with documented corporate risk-management policies, we monitor the amount of credit exposure to any one financial institution or corporate issuer. We are exposed to credit-related losses in the event of nonperformance by counterparties to risk-management instruments but do not expect any counterparties to fail to meet their obligations given their high credit ratings.

We consider all highly liquid investments with a maturity of three months or less from the date of purchase to be cash equivalents. The cost of these investments approximates fair value.

Our equity investments are accounted for using three different methods depending on the type of equity investment:


•	Investments in companies over which we have significant influence but not a controlling interest are accounted for using the equity method, with our share of earnings or losses reported in other-net, (income) expense.


•	For equity investments that do not have readily determinable fair values, we measure these investments at cost, less any impairment, plus or minus changes resulting from observable price changes in orderly transactions for the identical or similar investment of the same issuer. Any change in recorded value is recorded in other-net, (income) expense.


•	Our public equity investments are measured and carried at fair value. Any change in fair value is recognized in other-net, (income) expense.

We review equity investments other than public equity investments for indications of impairment and observable price changes on a regular basis.

Our derivative activities are initiated within the guidelines of documented corporate risk-management policies and are intended to offset losses and gains on the assets, liabilities, and transactions being hedged. Management reviews the correlation and effectiveness of our derivatives on a quarterly basis.

For derivative instruments that are designated and qualify as fair value hedges, the derivative instrument is marked to market, with gains and losses recognized currently in income to offset the respective losses and gains recognized on the underlying exposure. For derivative instruments that are designated and qualify as cash flow hedges, gains and losses are reported as a component of accumulated other comprehensive loss and reclassified into earnings in the same period the hedged transaction affects earnings. For derivative and non-derivative instruments that are designated and qualify as net investment hedges, the foreign currency translation gains or losses due to spot rate fluctuations are reported as a component of accumulated other comprehensive loss. Derivative contracts that are not designated as hedging instruments are recorded at fair value with the gain or loss recognized in earnings during the period of change.

We may enter into foreign currency forward or option contracts to reduce the effect of fluctuating currency exchange rates (principally the euro, British pound, and the Japanese yen). Foreign currency derivatives used for hedging are put in place using the same or like currencies and duration as the underlying exposures. Forward and option contracts are principally used to manage exposures arising from subsidiary trade and loan payables and receivables denominated in foreign currencies. These contracts are recorded at fair value with the gain or loss recognized in other–net, (income) expense. We may enter into foreign currency forward and option contracts and currency swaps as fair value hedges of firm commitments. Forward contracts generally have maturities not exceeding 12 months. At June 30, 2019, we had outstanding foreign currency forward commitments to purchase 605.3 million U.S. dollars and sell 535.9 million euro, commitments to purchase 1.14 billion euro and sell 1.28 billion U.S. dollars, commitments to purchase 279.4 million U.S. dollars and sell 30.22 billion Japanese yen, and commitments to purchase 237.6 million British pounds and sell 299.7 million U.S. dollars, which will all settle within 30 days.

Foreign currency exchange risk is also managed through the use of foreign currency debt and cross-currency interest rate swaps. Our foreign currency-denominated notes had carrying amounts of $3.38 billion and $3.40 billion as of June 30, 2019 and December 31, 2018, respectively, of which $2.36 billion and $2.38 billion have been designated as, and are effective as, economic hedges of net investments in certain of our euro-denominated foreign operations as of June 30, 2019 and December 31, 2018, respectively. At June 30, 2019, we had outstanding cross currency swaps with notional amounts of $1.93 billion swapping U.S. dollars to euro, $1.00 billion swapping Swiss francs to U.S. dollars, and $143.0 million swapping U.S. dollars to British pounds, which have settlement dates ranging through 2028. Our cross-currency interest rate swaps, for which a majority convert a portion of our U.S. dollar-denominated floating rate debt to foreign-denominated floating rate debt, have also been designated as, and are effective as, economic hedges of net investments.

In the normal course of business, our operations are exposed to fluctuations in interest rates which can vary the costs of financing, investing, and operating. We seek to address a portion of these risks through a controlled program of risk management that includes the use of derivative financial instruments. The objective of controlling these risks is to limit the impact of fluctuations in interest rates on earnings. Our primary interest-rate risk exposure results from changes in short-term U.S. dollar interest rates. In an effort to manage interest-rate exposures, we strive to achieve an acceptable balance between fixed- and floating-rate debt and investment positions and may enter into interest rate swaps or collars to help maintain that balance.

Interest rate swaps or collars that convert our fixed-rate debt to a floating rate are designated as fair value hedges of the underlying instruments. Interest rate swaps or collars that convert floating-rate debt to a fixed rate are designated as cash flow hedges. Interest expense on the debt is adjusted to include the payments made or received under the swap agreements. Cash proceeds from or payments to counterparties resulting from the termination of interest rate swaps are classified as operating activities in our consolidated condensed statements of cash flows. At June 30, 2019, substantially all of our total long-term debt is at a fixed rate. We have converted approximately 15 percent of our long-term fixed-rate notes to floating rates through the use of interest rate swaps.

We also may enter into forward-starting interest rate swaps, which we designate as cash flow hedges, as part of any anticipated future debt issuances in order to reduce the risk of cash flow volatility from future changes in interest rates. The change in fair value of these instruments is recorded as part of other comprehensive income (loss), and upon completion of a debt issuance and termination of the swap, is amortized to interest expense over the life of the underlying debt.

In February 2019, we issued $1.15 billion of 3.38 percent fixed-rate notes due in March 2029, $850.0 million of 3.88 percent fixed-rate notes due in March 2039, $1.50 billion of 3.95 percent fixed-rate notes due in March 2049, and $1.00 billion of 4.15 percent fixed-rate notes due in March 2059, with interest to be paid semi-annually. We used the net proceeds of $4.45 billion from the sale of these notes to fund the acquisition of Loxo and for general corporate purposes.

The Effect of Risk-Management Instruments on the Consolidated Condensed Statements of Operations

The following effects of risk-management instruments were recognized in other–net, (income) expense:



	Three Months Ended June 30,						Six Months Ended June 30,
	2019			2018			2019			2018
Fair value hedges:
Effect from hedged fixed-rate debt	$	59.3		$	(19.7	)	$	98.5		$	(74.5	)
Effect from interest rate contracts	(59.3		)	19.7			(98.5		)	74.5
Cash flow hedges:
Effective portion of losses on interest rate contracts reclassified from accumulated other comprehensive loss	4.0			3.7			7.8			7.3
Net (gains) losses on foreign currency exchange contracts not designated as hedging instruments	(8.5		)	59.1			40.4			75.7
Total	$	(4.5	)	$	62.8		$	48.2		$	83.0

During the three and six months ended June 30, 2019 and 2018, the amortization of losses related to the portion of our risk management hedging instruments, fair value hedges, and cash flow hedges that was excluded from the assessment of effectiveness was not material.

The Effect of Risk-Management Instruments on Other Comprehensive Income (Loss)

The effective portion of risk-management instruments that was recognized in other comprehensive income (loss) is as follows:



	Three Months Ended June 30,					Six Months Ended June 30,
	2019			2018		2019			2018
Net investment hedges:
Foreign currency-denominated notes	$	(30.4	)	$	208.5	$	23.3		$	100.8
Cross-currency interest rate swaps	(4.3		)	69.1		34.0			37.6
Cash flow hedges:
Forward-starting interest rate swaps	—			—		(11.7		)	—
Cross-currency interest rate swaps	(7.4		)	—		(37.5		)	—

During the next 12 months, we expect to reclassify $16.2 million of pretax net losses on cash flow hedges from accumulated other comprehensive loss to other–net, (income) expense. During the three and six months ended June 30, 2019, the amounts excluded from the assessment of hedge effectiveness recognized in other comprehensive income (loss) were not material.

Fair Value of Financial Instruments

The following tables summarize certain fair value information at June 30, 2019 and December 31, 2018 for assets and liabilities measured at fair value on a recurring basis, as well as the carrying amount and amortized cost of certain other investments:



					Fair Value Measurements Using
	Carrying Amount		Cost ⁽¹⁾		Quoted Prices in Active Markets for Identical Assets (Level 1)		Significant Other Observable Inputs (Level 2)		Significant Unobservable Inputs (Level 3)		Fair Value
June 30, 2019
Cash equivalents	$	982.1	$	982.1	$	982.1	$	—	$	—	$	982.1

Short-term investments:
U.S. government and agency securities	$	3.9	$	3.9	$	3.9	$	—	$	—	$	3.9
Corporate debt securities	72.4		72.3		—		72.4		—		72.4
Other securities	1.4		1.4		—		1.4		—		1.4
Short-term investments	$	77.7

Noncurrent investments:
U.S. government and agency securities	$	82.3	$	81.6	$	82.3	$	—	$	—	$	82.3
Corporate debt securities	411.2		408.0		—		411.2		—		411.2
Mortgage-backed securities	95.1		94.4		—		95.1		—		95.1
Asset-backed securities	33.3		33.0		—		33.3		—		33.3
Other securities	82.1		40.0		—		—		82.1		82.1
Marketable equity securities	466.5		228.0		466.5		—		—		466.5
Equity investments without readily determinable fair values ⁽²⁾	398.6
Equity method investments ⁽²⁾	283.6
Noncurrent investments	$	1,852.7

December 31, 2018
Cash equivalents	$	5,727.1	$	5,727.1	$	5,727.1	$	—	$	—	$	5,727.1

Short-term investments:
U.S. government and agency securities	$	16.9	$	17.1	$	16.9	$	—	$	—	$	16.9
Corporate debt securities	62.2		62.6		—		62.2		—		62.2
Asset-backed securities	7.6		7.7		—		7.6		—		7.6
Other securities	1.5		1.5		—		1.5		—		1.5
Short-term investments	$	88.2

Noncurrent investments:
U.S. government and agency securities	$	149.1	$	153.6	$	149.1	$	—	$	—	$	149.1
Corporate debt securities	568.0		587.8		—		568.0		—		568.0
Mortgage-backed securities	111.4		114.5		—		111.4		—		111.4
Asset-backed securities	27.7		27.9		—		27.7		—		27.7
Other securities	87.8		29.7		—		—		87.8		87.8
Marketable equity securities	357.5		238.3		357.5		—		—		357.5
Equity investments without readily determinable fair values ⁽²⁾	414.7
Equity method investments ⁽²⁾	289.2
Noncurrent investments	$	2,005.4

⁽¹⁾For available-for-sale debt securities, amounts disclosed represent the securities' amortized cost.

⁽²⁾Fair value disclosures are not applicable for equity method investments and investments accounted for under the measurement alternative for equity investments.



				Fair Value Measurements Using
	Carrying Amount			Quoted Prices in Active Markets for Identical Assets (Level 1)		Significant Other Observable Inputs (Level 2)			Significant Unobservable Inputs (Level 3)		Fair Value
Short-term commercial paper borrowings
June 30, 2019	$	(2,058.3	)	$	—	$	(2,049.8	)	$	—	$	(2,049.8	)
December 31, 2018	(498.9		)	—		(497.6		)	—		(497.6		)
Long-term debt, including current portion
June 30, 2019	$	(13,727.9	)	$	—	$	(14,833.0	)	$	—	$	(14,833.0	)
December 31, 2018	(9,799.7		)	—		(9,970.0		)	—		(9,970.0		)



				Fair Value Measurements Using
	Carrying Amount			Quoted Prices in Active Markets for Identical Assets (Level 1)		Significant Other Observable Inputs (Level 2)			Significant Unobservable Inputs (Level 3)		Fair Value
June 30, 2019
Risk-management instruments:
Interest rate contracts designated as fair value hedges:
Sundry	$	82.4		$	—	$	82.4		$	—	$	82.4
Cross-currency interest rate contracts designated as net investment hedges:
Other receivables	16.9			—		16.9			—		16.9
Sundry	26.4			—		26.4			—		26.4
Other current liabilities	(3.6		)	—		(3.6		)	—		(3.6		)
Other noncurrent liabilities	(2.1		)	—		(2.1		)	—		(2.1		)
Cross-currency interest rate contracts designated as cash flow hedges:
Other noncurrent liabilities	(19.0		)	—		(19.0		)	—		(19.0		)
Foreign exchange contracts not designated as hedging instruments:
Other receivables	17.6			—		17.6			—		17.6
Other current liabilities	(11.7		)	—		(11.7		)	—		(11.7		)

December 31, 2018
Risk-management instruments:
Interest rate contracts designated as fair value hedges:
Sundry	4.5			—		4.5			—		4.5
Other current liabilities	(22.3		)	—		(22.3		)	—		(22.3		)
Other noncurrent liabilities	(19.0		)	—		(19.0		)	—		(19.0		)
Cross-currency interest rate contracts designated as net investment hedges:
Other receivables	69.2			—		69.2			—		69.2
Sundry	8.2			—		8.2			—		8.2
Other current liabilities	(9.2		)	—		(9.2		)	—		(9.2		)
Cross-currency interest rate contracts not designated as hedging instruments
Other noncurrent liabilities	(25.8		)	—		(25.8		)	—		(25.8		)
Foreign exchange contracts not designated as hedging instruments:
Other receivables	11.3			—		11.3			—		11.3
Other current liabilities	(16.3		)	—		(16.3		)	—		(16.3		)

Risk-management instruments above are disclosed on a gross basis. There are various rights of setoff associated with certain of the risk-management instruments above that are subject to an enforceable master netting arrangement or similar agreements. Although various rights of setoff and master netting arrangements or similar agreements may exist with the individual counterparties to the risk-management instruments above, individually, these financial rights are not material.

We determine our Level 1 and Level 2 fair value measurements based on a market approach using quoted market values, significant other observable inputs for identical or comparable assets or liabilities, or discounted cash flow analyses. Level 3 fair value measurements for other investment securities are determined using unobservable inputs, including the investments' cost adjusted for impairments and price changes from orderly transactions. The fair values of equity method investments and investments measured under the measurement alternative for equity investments that do not have readily determinable fair values are not readily available.

The table below summarizes the contractual maturities of our investments in debt securities measured at fair value as of June 30, 2019:



	Maturities by Period
	Total		Less Than 1 Year		1-5 Years		6-10 Years		More Than 10 Years
Fair value of debt securities	$	698.3	$	76.3	$	447.1	$	61.4	$	113.5

The net unrealized gains recognized in our consolidated condensed statements of operations for equity securities were $6.3 million and $156.0 million for the three and six months ended June 30, 2019, respectively, and $20.8 million and $38.6 million for the three and six months ended June 30, 2018, respectively.

We adjust our equity investments without readily determinable fair values based upon changes in the equity instruments' values resulting from observable price changes in orderly transactions for an identical or similar investment of the same issuer. Downward adjustments resulting from an impairment are recorded based upon impairment considerations, including the financial condition and near term prospects of the issuer, general market conditions, and industry specific factors. Adjustments recorded during the three and six months ended June 30, 2019 and 2018 were not material.

A summary of the fair value of available-for-sale securities in an unrealized gain or loss position and the amount of unrealized gains and losses (pretax) in accumulated other comprehensive loss follows:



	June 30, 2019		December 31, 2018
Unrealized gross gains	$	9.3	$	0.8
Unrealized gross losses	4.1		29.0
Fair value of securities in an unrealized gain position	441.9		84.3
Fair value of securities in an unrealized loss position	255.8		858.6

We periodically assess our investment in available-for-sale securities for other-than-temporary impairment losses. Other than temporary impairment losses were not material in the three and six months ended June 30, 2019. There were no other-than-temporary impairment losses in the three or six months ended June 30, 2018.

For debt securities, the amount of credit losses are determined by comparing the difference between the present value of future cash flows expected to be collected on these securities and the amortized cost. Factors considered in assessing credit losses include the position in the capital structure, vintage and amount of collateral, delinquency rates, current credit support, and geographic concentration.

As of June 30, 2019, the available-for-sale securities in an unrealized loss position include primarily fixed-rate debt securities of varying maturities, which are sensitive to changes in the yield curve and other market conditions. Approximately 40 percent of the fixed-rate debt securities in a loss position are investment-grade debt securities. As of June 30, 2019, we do not intend to sell, and it is not more likely than not that we will be required to sell the securities in a loss position before the market values recover or the underlying cash flows have been received, and there is no indication of default on interest or principal payments for any of our debt securities.

Activity related to our investment portfolio, substantially all of which related to equity and available-for-sale securities, was as follows:



	Three Months Ended June 30,				Six Months Ended June 30,
	2019		2018		2019		2018
Proceeds from sales	$	362.9	$	4,953.8	$	456.6	$	5,546.4
Realized gross gains on sales	13.0		5.6		15.5		7.7
Realized gross losses on sales	6.4		47.4		6.8		49.0

Realized gains and losses on sales of available-for-sale investments are computed based upon specific identification of the initial cost adjusted for any other-than-temporary declines in fair value that were recorded in earnings.

Accounts Receivable Factoring Arrangements

We have entered into accounts receivable factoring agreements with financial institutions to sell certain of our non-U.S. accounts receivable. These transactions are accounted for as sales and result in a reduction in accounts receivable because the agreements transfer effective control over and risk related to the receivables to the buyers. Our factoring agreements do not allow for recourse in the event of uncollectibility, and we do not retain any interest in the underlying accounts receivable once sold. We derecognized $696.4 million and $696.2 million of accounts receivable as of June 30, 2019 and December 31, 2018, respectively, under these factoring arrangements. The costs of factoring such accounts receivable on our consolidated condensed results of operations for the three and six months ended June 30, 2019 and 2018 were not material.

Defined Benefit Plans and Other Postretirement Benefit Plans Disclosures [Abstract]

The entire disclosure for the fair value of financial instruments (as defined), including financial assets and financial liabilities (collectively, as defined), and the measurements of those instruments as well as disclosures related to the fair value of non-financial assets and liabilities. Such disclosures about the financial instruments, assets, and liabilities would include: (1) the fair value of the required items together with their carrying amounts (as appropriate); (2) for items for which it is not practicable to estimate fair value, disclosure would include: (a) information pertinent to estimating fair value (including, carrying amount, effective interest rate, and maturity, and (b) the reasons why it is not practicable to estimate fair value; (3) significant concentrations of credit risk including: (a) information about the activity, region, or economic characteristics identifying a concentration, (b) the maximum amount of loss the entity is exposed to based on the gross fair value of the related item, (c) policy for requiring collateral or other security and information as to accessing such collateral or security, and (d) the nature and brief description of such collateral or security; (4) quantitative information about market risks and how such risks are managed; (5) for items measured on both a recurring and nonrecurring basis information regarding the inputs used to develop the fair value measurement; and (6) for items presented in the financial statement for which fair value measurement is elected: (a) information necessary to understand the reasons for the election, (b) discussion of the effect of fair value changes on earnings, (c) a description of [similar groups] items for which the election is made and the relation thereof to the balance sheet, the aggregate carrying value of items included in the balance sheet that are not eligible for the election; (7) all other required (as defined) and desired information.

+ References + Details

Leases

6 Months Ended

Jun. 30, 2019

Leases [Abstract]

Leases

We determine if an arrangement is a lease at inception. We have leases with terms up to 13 years for corporate offices, research and development facilities, vehicles, and equipment, including some of which have options to extend and/or early-terminate the leases. We determine the lease term by assuming the exercise of any renewal and/or early-termination options that are reasonably assured.

Beginning January 1, 2019, operating lease right-of-use assets have been presented in operating lease assets in our consolidated condensed balance sheet, and the current and long-term portions of operating lease liabilities are included in other current liabilities and noncurrent operating lease liabilities, respectively, in our consolidated condensed balance sheet. Short-term leases, which are deemed at inception to have a lease term of 12 months or less, are not recorded on the consolidated condensed balance sheet.

Operating lease assets represent our right to use an underlying asset for the lease term and operating lease liabilities represent our obligation to make lease payments arising from the lease. Operating lease assets and liabilities are recognized at commencement date based on the present value of lease payments over the lease term. As most of our leases do not provide an implicit rate, we use our incremental borrowing rate based on the information available at commencement date in determining the present value of lease payments.

Lease expense for operating lease assets, which is recognized on a straight-line basis over the lease term, was $34.0 million and $66.1 million, respectively, for the three and six months ended June 30, 2019. Variable lease payments, which represent non-lease components such as maintenance, insurance and taxes, and which vary due to changes in facts or circumstances occurring after the commencement date other than the passage of time, are expensed in the period in which the payment obligation is incurred and were not material during the three and six months ended June 30, 2019. Short-term lease expense was not material during the three and six months ended June 30, 2019.

Supplemental balance sheet information related to operating leases as of June 30, 2019 was as follows:




Weighted-average remaining lease term	8 years
Weighted-average discount rate	3.7	%

Supplemental cash flow information related to operating leases for the six months ended June 30, 2019 was as follows:




Operating cash flows from operating leases	$	72.7
Right-of-use assets obtained in exchange for new operating lease liabilities	46.2

The annual minimum lease payments of our operating lease liabilities as of June 30, 2019 were as follows:




Year 1	$	135.0
Year 2	113.9
Year 3	80.2
Year 4	67.6
Year 5	56.3
After Year 5	276.6
Total lease payments	729.6
Less imputed interest	(108.0		)
Total	$	621.6

Finance leases are included in property and equipment, short-term borrowings and current maturities of long-term debt, and long-term debt in our consolidated condensed balance sheets. Finance leases are not material to our consolidated condensed financial statements.

Leases

Supplemental balance sheet information related to operating leases as of June 30, 2019 was as follows:




Weighted-average remaining lease term	8 years
Weighted-average discount rate	3.7	%

Supplemental cash flow information related to operating leases for the six months ended June 30, 2019 was as follows:




Operating cash flows from operating leases	$	72.7
Right-of-use assets obtained in exchange for new operating lease liabilities	46.2

The annual minimum lease payments of our operating lease liabilities as of June 30, 2019 were as follows:




Year 1	$	135.0
Year 2	113.9
Year 3	80.2
Year 4	67.6
Year 5	56.3
After Year 5	276.6
Total lease payments	729.6
Less imputed interest	(108.0		)
Total	$	621.6

Income Taxes	6 Months Ended
Income Taxes	Jun. 30, 2019
Income Tax Disclosure [Abstract]
Income Taxes	Income Taxes The effective tax rates were 9.5 percent and 14.1 percent for the three and six months ended June 30, 2019, respectively. The effective tax rate for the three months ended June 30, 2019 reflects a net discrete tax benefit resulting from the resolution of certain global income tax audits. The effective tax rate for the six months ended June 30, 2019 reflects the non-deductibility of accelerated vesting of Loxo employee equity awards as part of the closing of the acquisition of Loxo, tax expenses associated with the suspension of promotion of Lartruvo^®, as well as the net discrete tax benefit resulting from the resolution of certain global income tax audits. During the three months ended June 30, 2018, we incurred $273.3 million of income tax expense, despite earning $41.7 million of income before income taxes, as a result of the non-deductible acquired IPR&D charges totaling $1.56 billion related to the acquisitions of ARMO and AurKa. The effective tax rate for the six months ended June 30, 2018 was 33.5 percent as it also reflected these non-deductible charges. In 2017, the U.S. enacted the Tax Cuts and Jobs Act (2017 Tax Act), which significantly revised U.S. tax law. Guidance related to the 2017 Tax Act, including Notices, Proposed Regulations, and Final Regulations, has been issued, and we expect additional guidance will be issued in the second half of 2019. This additional guidance could materially impact our assumptions and estimates used to record our U.S. federal and state income tax expense resulting from the 2017 Tax Act. The U.S. examination of tax years 2013-2015 began in 2016, and certain matters were effectively settled during the second quarter of 2019. As a result, our gross uncertain tax positions were reduced by approximately $200 million, we made a cash payment of approximately $125 million, and our consolidated condensed results of operations were benefited by an immaterial reduction in tax expense for three and six months ended June 30, 2019. The examination for tax year 2015 remains ongoing, and we believe it is reasonably possible that this examination could reach conclusion within the next 12 months. We currently estimate that gross uncertain tax positions may be reduced up to $100 million within the next 12 months.

Retirement Benefits

6 Months Ended

Jun. 30, 2019

Retirement Benefits

Net pension and retiree health benefit (income) cost included the following components:



	Defined Benefit Pension Plans						Defined Benefit Pension Plans
	Three Months Ended June 30,						Six Months Ended June 30,
	2019			2018			2019			2018
Components of net periodic benefit cost:
Service cost	$	63.5		$	74.9		$	125.4		$	152.5
Interest cost	122.6			111.4			243.3			223.3
Expected return on plan assets	(210.1		)	(210.0		)	(421.2		)	(420.9		)
Amortization of prior service cost	1.5			1.3			3.0			2.4
Recognized actuarial loss	73.1			91.1			142.7			181.1
Net periodic benefit cost	$	50.6		$	68.7		$	93.2		$	138.4



	Retiree Health Benefit Plans						Retiree Health Benefit Plans
	Three Months Ended June 30,						Six Months Ended June 30,
	2019			2018			2019			2018
Components of net periodic benefit income:
Service cost	$	9.4		$	10.9		$	18.2		$	21.6
Interest cost	14.4			13.5			29.0			27.4
Expected return on plan assets	(36.0		)	(43.9		)	(71.9		)	(87.8		)
Amortization of prior service benefit	(15.7		)	(20.4		)	(31.5		)	(40.9		)
Recognized actuarial loss	0.4			2.2			0.9			4.6
Net periodic benefit income	$	(27.5	)	$	(37.7	)	$	(55.3	)	$	(75.1	)

We contributed approximately $20 million required to satisfy minimum funding requirements to our defined benefit pension and retiree health benefit plans during the six months ended June 30, 2019. During the remainder of 2019, we expect to make contributions to our defined benefit pension and retiree health benefit plans of approximately $30 million to satisfy minimum funding requirements. There was no discretionary funding during the six months ended June 30, 2019, and none is planned for the remainder of 2019.

Contingencies	6 Months Ended
Contingencies	Jun. 30, 2019
Commitments and Contingencies Disclosure [Abstract]
Contingencies	Contingencies We are a party to various legal actions and government investigations. The most significant of these are described below. It is not possible to determine the outcome of these matters, and we cannot reasonably estimate the maximum potential exposure or the range of possible loss in excess of amounts accrued for any of these matters; however, we believe that, except as noted below with respect to the Alimta patent litigation and administrative proceedings, the resolution of all such matters will not have a material adverse effect on our consolidated financial position or liquidity, but could possibly be material to our consolidated results of operations in any one accounting period. Alimta Patent Litigation and Administrative Proceedings A number of generic manufacturers are seeking approvals in the U.S., a number of countries in Europe, and Japan to market generic forms of Alimta prior to the expiration of our vitamin regimen patents, alleging that those patents are invalid, not infringed, or both. We believe our Alimta vitamin regimen patents are valid and enforceable against these generic manufacturers. However, it is not possible to determine the ultimate outcome of the proceedings, and accordingly, we can provide no assurance that we will prevail. An unfavorable outcome in the U.S. could have a material adverse impact on our future consolidated results of operations, liquidity, and financial position. We expect that a loss of exclusivity for Alimta in any of the below jurisdictions would result in a rapid and severe decline in future revenue for the product in the relevant market. U.S. Patent Litigation and Administrative Proceedings In the U.S., more than 10 Abbreviated New Drug Applications (ANDAs) seeking approval to market generic versions of Alimta prior to the expiration of our vitamin regimen patent (expiring in 2021 plus pediatric exclusivity expiring in 2022) have been filed by a number of companies, including Teva Parenteral Medicines, Inc. (Teva) and APP Pharmaceuticals, LLC (APP) pursuant to procedures set out in the Drug Price Competition and Patent Term Restoration Act of 1984 (the Hatch-Waxman Act). We have received favorable decisions from the U.S. Court of Appeals for the Federal Circuit (affirming the U.S. District Court for the Southern District of Indiana's decisions finding our U.S. vitamin regimen patent valid and infringed) against Teva, APP, and two other defendants' proposed products, and similar favorable judgments have been entered by the U.S. District Court for the Southern District of Indiana against five other companies. In October 2017, the U.S. Patent and Trademark Office (USPTO) issued written decisions in our favor following inter partes review (IPR) of our U.S. vitamin regimen patent, finding that the generic company petitioners failed to show that the claims in our patent are unpatentable. In April 2019, the U.S. Court of Appeals for the Federal Circuit affirmed the written decisions of the USPTO IPR upholding our U.S. vitamin regimen patent. There are five remaining ANDA applicants who agreed to a preliminary injunction or stay pending the appeal of the IPR decision. In view of the Court of Appeals’ affirmance, we are re-engaging these remaining ANDA applicants to assess whether to reopen those cases or move for dismissal. We also currently have pending lawsuits in the U.S. District Court for the Southern District of Indiana alleging infringement against Actavis LLC (Actavis) and Apotex Inc. in response to their applications to market products using alternative forms of pemetrexed (the active ingredient in Alimta) products, and we filed a similar lawsuit in the U.S. District Court for the District of Delaware against Eagle Pharmaceuticals, Inc. In June 2018, the U.S. District Court for the Southern District of Indiana ruled in our favor in two similar cases, finding Dr. Reddy's Laboratories' (Dr. Reddy) and Hospira, Inc.'s (Hospira) proposed products would infringe our patent. Dr. Reddy and Hospira have appealed those rulings and the U.S. Court of Appeals for the Federal Circuit heard oral argument in June 2019. We expect a decision from the Court of Appeals in the third quarter of 2019. The lawsuit against Actavis has been stayed, pending a decision in the Dr. Reddy’s and Hospira’s appeals. European Patent Litigation and Administrative Proceedings In July 2017, the United Kingdom (U.K.) Supreme Court ruled that commercialization of certain salt forms of pemetrexed by Actavis Group ehf and other Actavis companies directly infringes our vitamin regimen patents in the U.K., Italy, France, and Spain. This litigation in the U.K. is now concluded. Hexal AG, Stada Arzneimittel AG (Stada), and Fresenius Kabi Deutschland GmbH have each challenged the validity of our German vitamin regimen patent before the German Federal Patent Court. At a hearing in July 2018, the German Federal Patent Court held that our German vitamin regimen patent is invalid. We have appealed this decision to the German Supreme Court. Under German law, the patent remains in force pending appeal. A number of generic competitors have received approval to market generic versions of pemetrexed in Germany. Some of these companies, including Stada, have launched at risk or may choose to launch at risk. We are seeking injunctions and/or contesting the lifting of previously granted injunctions against these companies while the appeal to the German Supreme Court is pending. Alimta revenue in Germany has steadily decreased over the last few quarters and is not material to our business. Additional legal proceedings are ongoing in various national courts throughout Europe. We are aware that several companies have received approval to market generic versions of pemetrexed in major European markets (including generics currently on the market at risk in France) and that additional generic competitors may choose to launch at risk. We will continue to seek to remove any generic pemetrexed products launched at risk in European markets, including Germany and France, seek damages with respect to such launches, and defend our patents against validity challenges. Japanese Administrative Proceedings Three separate sets of demands for invalidation of our two Japanese vitamin regimen patents, involving several companies, have been filed with the Japanese Patent Office (JPO). The JPO rejected a demand for invalidation by Sawai Pharmaceutical Co., Ltd., which was affirmed on appeal in 2017. In July 2018, the JPO issued written decisions dismissing demands brought by Nipro Corporation (Nipro) for invalidation of our two Japanese vitamin regimen patents. Nipro filed an appeal, and we anticipate decisions by the Japan Intellectual Property High Court in the fourth quarter of 2019. We also anticipate decisions by the JPO with respect to another set of demands, brought by Hospira, in the fourth quarter of 2019. If upheld through all challenges, these patents would provide intellectual property protection for Alimta until June 2021. Notwithstanding our patents, generic versions of Alimta received regulatory approval in Japan starting in February 2016. We do not currently anticipate that generic versions of Alimta will proceed to pricing approval. Cymbalta Product Liability Litigation We were named as a defendant in a purported class-action lawsuit in the U.S. District Court for the Central District of California (now called Strafford et al. v. Eli Lilly and Company) involving Cymbalta. The plaintiffs, purporting to represent a class of all persons within the U.S. who purchased and/or paid for Cymbalta, asserted claims under the consumer protection statutes of California, Massachusetts, Missouri, and New York, and sought declaratory, injunctive, and monetary relief for various alleged economic injuries arising from discontinuing treatment with Cymbalta. The district court denied the plaintiffs' motions for class certification and dismissed the suits. The plaintiffs subsequently appealed to the U.S. Court of Appeals for the Ninth Circuit. In November 2017, the U.S. Court of Appeals for the Ninth Circuit dismissed the suit. In July 2018, the U.S. District Court for the District of California denied plaintiffs’ motion to reopen the case. Plaintiffs’ appeal of this denial is currently pending before the U.S. Court of Appeals for the Ninth Circuit. Brazil Litigation – Cosmopolis Facility Our subsidiary in Brazil, Eli Lilly do Brasil Limitada (Lilly Brasil), is named in a lawsuit brought by the Labor Attorney for the 15th Region in the Labor Court of Paulinia, State of Sao Paulo, Brazil, alleging possible harm to employees and former employees caused by exposure to heavy metals at a former Lilly Brasil manufacturing facility in Cosmopolis, Brazil, operated by the company between 1977 and 2003. In May 2014, the labor court judge ruled against Lilly Brasil, ordering it to undertake several actions of unspecified financial impact, including paying lifetime medical insurance for the employees and contractors who worked at the Cosmopolis facility more than six months during the affected years and their children born during and after this period. We appealed this decision. In July 2018, the appeals court affirmed the labor court's ruling with the total financial impact of the ruling estimated to be approximately 500 million Brazilian real (approximately $130 million as of June 30, 2019). The appeals court restricted the broad health coverage awarded by the labor court to health problems that claimants could show arose from exposure to the alleged contamination. We strongly disagree with the appeals and labor court's decisions. Lilly Brasil has taken an initial step in the appeal process by filing a Motion for Clarification. In July 2019, the appeals court announced orally that it has ruled on our Motion for Clarification and we expect its written decision to be published in the third quarter of 2019. In June 2019, the Labor Attorney filed an application in the labor court for enforcement of the healthcare coverage granted by the appeals court in its July 2018 ruling and requested restrictions on Lilly Brasil’s assets in Brazil. In July 2019, the labor court issued a ruling requiring either a freeze of Lilly Brasil’s immovable property or, alternatively, a security deposit of 500 million Brazilian real (approximately $130 million as of June 30, 2019). We strongly disagree with this decision and plan to take steps to challenge it. The labor court stayed the Labor Attorney’s application to enforce the previous healthcare coverage ruling until after the appeals court rules on the various motions pending before it, including Lilly Brasil’s Motion for Clarification. We are also named in approximately 30 lawsuits filed in the same labor court by individual former employees making similar claims. These lawsuits are each at various stages in the litigation process, with judgments being handed down in approximately half of the lawsuits, nearly all of which are on appeal in the labor courts. Lilly Brasil and Elanco Quimica Ltda. have been named in two similar lawsuits in the same labor court involving approximately 410 individual plaintiffs. We agreed to indemnify Elanco Quimica Ltda. in this litigation as part of the divestiture of Elanco. In the first lawsuit (involving approximately 305 plaintiffs), plaintiffs alleged harm to employees, former employees, and their dependents. In the second lawsuit (involving approximately 105 plaintiffs), plaintiffs alleged harm to contractors and suppliers, and their dependents. The plaintiffs’ claims in these two lawsuits relate only to mental anguish attributable to the possibility of illness due to alleged exposure to heavy metals or other contaminants. In 2017, the labor court dismissed the claims brought by all but the first named plaintiff in each of the lawsuits. The plaintiffs in both lawsuits appealed. In April 2019, the court issued a written decision rejecting the plaintiff’s appeal in the second lawsuit. The court’s decision was procedurally based and was without a judgment on the merits, meaning that the plaintiffs are able to bring individual actions, notwithstanding the court’s decision. We believe all of these lawsuits are without merit and are defending against them vigorously. Adocia, S.A. We have been named as a respondent in an arbitration filed by Adocia, S.A. (Adocia), with which we entered into agreements for the co-development of an ultra-rapid insulin product. Adocia alleges that we misappropriated and misused Adocia's confidential information and intellectual property and is seeking approximately $1.39 billion in damages and other specific relief. We have asserted several counterclaims relating to fraudulent misrepresentation and are seeking approximately $188 million in damages. An arbitration hearing was held on Adocia’s claims and our counterclaims in December 2018, and we expect a decision in the third quarter of 2019. We believe Adocia's claims are without merit and have defended against them vigorously. Throughout the dispute process, Adocia has made statements alleging that Adocia employees should be listed as inventors on two of our patents related to our ultra-rapid insulin product currently in development. We strongly contest this allegation. While inventorship of these two patents was not at issue in the arbitration proceedings, in October 2018 we filed a declaratory judgment action against Adocia in the U.S. District Court for the Southern District of Indiana to confirm our inventorship. Insulin Pricing Litigation and Investigations We, along with Sanofi and Novo Nordisk, are named as defendants in a consolidated purported class action lawsuit, In re. Insulin Pricing Litigation, in the U.S. District Court of New Jersey relating to insulin pricing. Plaintiffs seek damages under various state consumer protection laws and the Federal Racketeer Influenced and Corrupt Organization Act (federal RICO Act). Separately, we, along with Sanofi and Novo Nordisk, are named as defendants in a purported class action lawsuit, MSP Recovery Claims, Series, LLC et al. v. Sanofi Aventis U.S. LLC et al., in the same court, seeking damages under various state consumer protection laws, common law fraud, unjust enrichment, and the federal RICO Act. In March 2019, the court dismissed, without prejudice, the plaintiffs' federal RICO Act, unjust enrichment, and certain state consumer protection law claims. Plaintiffs in that lawsuit filed a second amended complaint in April 2019 reasserting these claims. The Minnesota Attorney General’s Office filed a complaint against us, Sanofi, and Novo Nordisk, State of Minnesota v. Sanofi-Aventis U.S. LLC et al., in the U.S. District Court of New Jersey, alleging unjust enrichment, and violations of various Minnesota state consumer protection laws and the federal RICO Act. Additionally, the Kentucky Attorney General’s Office filed a complaint against us, Sanofi, and Novo Nordisk, Commonwealth of Kentucky v. Novo Nordisk, Inc. et al., in Kentucky state court, alleging violations of the Kentucky consumer protection law, false advertising, and unjust enrichment. We believe all of these claims are without merit and are defending against them vigorously. We have received a subpoena from the New York Attorney General’s Office and civil investigative demands from the Washington and New Mexico Attorney General Offices relating to the pricing and sale of our insulin products. The Offices of the Attorney General in Mississippi, Washington D.C., California, Florida, Hawaii, and Nevada have requested information relating to the pricing and sale of our insulin products. We received interrogatories from the California Attorney General's Office regarding our competition in the long-acting insulin market. Finally, we received and have complied with two requests from the House of Representatives’ Committee on Energy and Commerce and a request from the Senate’s Committee on Health, Education, Labor, and Pensions, seeking certain information related to the pricing of insulin products, among other issues. We also received a request from the House of Representatives’ Committee on Oversight and Reform and one from the Senate’s Committee on Finance, both of which seek detailed commercial information and business records. We are cooperating with all of these aforementioned requests and investigations. Product Liability Insurance Because of the nature of pharmaceutical products, it is possible that we could become subject to large numbers of additional product liability and related claims in the future. Due to a very restrictive market for product liability insurance, we are self-insured for product liability losses for all our currently and previously marketed products.

Other Comprehensive Income (Loss)

6 Months Ended

Jun. 30, 2019

Statement of Comprehensive Income [Abstract]

Other Comprehensive Income (Loss)

The following tables summarize the activity related to each component of other comprehensive income (loss) during the three months ended June 30, 2019 and 2018:



	Continuing Operations
(Amounts presented net of taxes)	Foreign Currency Translation Gains (Losses)			Unrealized Net Gains (Losses) on Securities			Defined Benefit Pension and Retiree Health Benefit Plans			Effective Portion of Cash Flow Hedges			Discontinued Operations		Accumulated Other Comprehensive Loss
Balance at April 1, 2019	$	(1,601.4	)	$	(3.6	)	$	(3,813.7	)	$	(268.8	)	$	—	$	(5,687.5	)

Other comprehensive income (loss) before reclassifications	31.4			8.4			3.4			(6.1		)	—		37.1
Net amount reclassified from accumulated other comprehensive loss	—			(0.3		)	47.0			3.2			—		49.9
Net other comprehensive income (loss)	31.4			8.1			50.4			(2.9		)	—		87.0

Balance at June 30, 2019	$	(1,570.0	)	$	4.5		$	(3,763.3	)	$	(271.7	)	$	—	$	(5,600.5	)



	Continuing Operations
(Amounts presented net of taxes)	Foreign Currency Translation Gains (Losses)			Unrealized Net Gains (Losses) on Securities			Defined Benefit Pension and Retiree Health Benefit Plans			Effective Portion of Cash Flow Hedges			Discontinued Operations			Accumulated Other Comprehensive Loss
Balance at April 1, 2018	$	(900.2	)	$	(51.0	)	$	(4,274.4	)	$	(231.5	)	$	19.6		$	(5,437.5	)

Other comprehensive income (loss) before reclassifications	(661.3		)	65.9			55.8			0.1			(160.9		)	(700.4		)
Net amount reclassified from accumulated other comprehensive loss	—			(33.0		)	58.6			2.9			0.7			29.2
Net other comprehensive income (loss)	(661.3		)	32.9			114.4			3.0			(160.2		)	(671.2		)

Balance at June 30, 2018	$	(1,561.5	)	$	(18.1	)	$	(4,160.0	)	$	(228.5	)	$	(140.6	)	$	(6,108.7	)

The following tables summarize the activity related to each component of other comprehensive income (loss) during the six months ended June 30, 2019 and 2018:



	Continuing Operations
(Amounts presented net of taxes)	Foreign Currency Translation Gains (Losses)			Unrealized Net Gains (Losses) on Securities			Defined Benefit Pension and Retiree Health Benefit Plans			Effective Portion of Cash Flow Hedges			Discontinued Operations			Accumulated Other Comprehensive Loss
Balance at January 1, 2019 ⁽¹⁾	$	(1,569.7	)	$	(22.1	)	$	(3,852.7	)	$	(238.9	)	$	(56.8	)	$	(5,740.2	)

Other comprehensive income (loss) before reclassifications	(0.3		)	25.2			(2.3		)	(39.0		)	(27.2		)	(43.6		)
Net amount reclassified from accumulated other comprehensive loss	—			1.4			91.7			6.2			84.0			183.3
Net other comprehensive income (loss)	(0.3		)	26.6			89.4			(32.8		)	56.8			139.7

Balance at June 30, 2019	$	(1,570.0	)	$	4.5		$	(3,763.3	)	$	(271.7	)	$	—		$	(5,600.5	)



	Continuing Operations
(Amounts presented net of taxes)	Foreign Currency Translation Gains (Losses)			Unrealized Net Gains (Losses) on Securities			Defined Benefit Pension and Retiree Health Benefit Plans			Effective Portion of Cash Flow Hedges			Discontinued Operations			Accumulated Other Comprehensive Loss
Balance at January 1, 2018 ⁽²⁾	$	(1,191.7	)	$	113.5		$	(4,311.3	)	$	(234.3	)	$	(71.1	)	$	(5,694.9	)

Reclassification due to adoption of new accounting standard ⁽³⁾	—			(128.9		)	—			—			—			(128.9		)
Other comprehensive income (loss) before reclassifications	(369.8		)	29.9			35.0			—			(70.9		)	(375.8		)
Net amount reclassified from accumulated other comprehensive loss	—			(32.6		)	116.3			5.8			1.4			90.9
Net other comprehensive income (loss)	(369.8		)	(2.7		)	151.3			5.8			(69.5		)	(284.9		)

Balance at June 30, 2018	$	(1,561.5	)	$	(18.1	)	$	(4,160.0	)	$	(228.5	)	$	(140.6	)	$	(6,108.7	)

⁽¹⁾Accumulated other comprehensive loss as of January 1, 2019 consists of $5.73 billion of accumulated other comprehensive loss attributable to controlling interest and $11.0 million of accumulated other comprehensive loss attributable to noncontrolling interest.

⁽²⁾Accumulated other comprehensive loss as of January 1, 2018 consists of $5.72 billion of accumulated other comprehensive loss attributable to controlling interest and $23.7 million of accumulated other comprehensive income attributable to noncontrolling interest.

⁽³⁾This reclassification consists of $105.2 million of accumulated other comprehensive loss attributable to controlling interest and $23.7 million of accumulated other comprehensive loss attributable to noncontrolling interest.

The tax effects on the net activity related to each component of other comprehensive income (loss) were as follows:



	Three Months Ended June 30,						Six Months Ended June 30,
Tax benefit (expense)	2019			2018			2019			2018
Foreign currency translation gains/losses	$	7.3		$	(58.3	)	$	(12.0	)	$	(18.2	)
Unrealized net gains/losses on securities	(2.1		)	(8.9		)	(6.9		)	1.3
Defined benefit pension and retiree health benefit plans	(13.4		)	(23.6		)	(24.8		)	(37.9		)
Effective portion of cash flow hedges	0.7			(0.7		)	8.7			(1.5		)
Benefit/(provision) for income taxes allocated to other comprehensive income (loss) items	$	(7.5	)	$	(91.5	)	$	(35.0	)	$	(56.3	)

Except for the tax effects of foreign currency translation gains and losses related to our foreign currency-denominated notes, cross-currency interest rate swaps, and other foreign currency exchange contracts designated as net investment hedges (see Note 7), income taxes were not provided for foreign currency translation. Generally, the assets and liabilities of foreign operations are translated into U.S. dollars using the current exchange rate. For those operations, changes in exchange rates generally do not affect cash flows; therefore, resulting translation adjustments are made in shareholders' equity rather than in the consolidated condensed statements of operations.

Reclassifications out of accumulated other comprehensive loss were as follows:



Details about Accumulated Other Comprehensive Loss Components	Three Months Ended June 30,						Six Months Ended June 30,						Affected Line Item in the Consolidated Condensed Statements of Operations
	Three Months Ended June 30,						Six Months Ended June 30,
	2019			2018			2019			2018
Amortization of retirement benefit items:
Prior service benefits, net	$	(14.2	)	$	(19.1	)	$	(28.5	)	$	(38.5	)	Other–net, (income) expense
Actuarial losses, net	73.5			93.3			143.6			185.7			Other–net, (income) expense
Total before tax	59.3			74.2			115.1			147.2
Tax benefit	(12.3		)	(15.6		)	(23.4		)	(30.9		)	Income taxes
Net of tax	47.0			58.6			91.7			116.3

Other, net of tax	2.9			(30.1		)	7.6			(26.8		)	Other–net, (income) expense
Reclassifications from continuing operations (net of tax)	49.9			28.5			99.3			89.5
Reclassifications from discontinued operations (net of tax)	—			0.7			84.0			1.4			Net income from discontinued operations
Total reclassifications for the period (net of tax)	$	49.9		$	29.2		$	183.3		$	90.9

Other–Net, (Income) Expense

6 Months Ended

Jun. 30, 2019

Nonoperating Income (Expense) [Abstract]

Other–Net, (Income) Expense

Other–net, (income) expense consisted of the following:



	Three Months Ended June 30,						Six Months Ended June 30,
	2019			2018			2019			2018
Interest expense	$	110.9		$	63.3		$	197.4		$	124.5
Interest income	(19.4		)	(41.2		)	(50.0		)	(86.7		)
Retirement benefit plans	(49.8		)	(54.8		)	(105.7		)	(110.8		)
Other income	(9.3		)	(13.9		)	(95.3		)	(43.1		)
Other–net, (income) expense	$	32.4		$	(46.6	)	$	(53.6	)	$	(116.1	)

Acquisitions and Divestiture (Policies)	6 Months Ended
Acquisitions and Divestiture (Policies)	Jun. 30, 2019
Business Combinations [Abstract]
Business Combinations Policy	Under this method, the assets acquired and liabilities assumed were recorded at their respective fair values as of the acquisition date in our consolidated condensed financial statements. The determination of estimated fair value required management to make significant estimates and assumptions. The excess of the purchase price over the fair value of the acquired net assets, where applicable, has been recorded as goodwill. The results of operations of this acquisition have been included in our consolidated condensed financial statements from the date of acquisition.Upon acquisition, the acquired in-process research and development (IPR&D) charges related to these products were immediately expensed because the products had no alternative future use.

Financial Instruments (Policies)	6 Months Ended
Financial Instruments (Policies)	Jun. 30, 2019
Fair Value Disclosures [Abstract]
Description of Derivative Risk Management Policy	Our derivative activities are initiated within the guidelines of documented corporate risk-management policies and are intended to offset losses and gains on the assets, liabilities, and transactions being hedged. Management reviews the correlation and effectiveness of our derivatives on a quarterly basis. For derivative instruments that are designated and qualify as fair value hedges, the derivative instrument is marked to market, with gains and losses recognized currently in income to offset the respective losses and gains recognized on the underlying exposure. For derivative instruments that are designated and qualify as cash flow hedges, gains and losses are reported as a component of accumulated other comprehensive loss and reclassified into earnings in the same period the hedged transaction affects earnings. For derivative and non-derivative instruments that are designated and qualify as net investment hedges, the foreign currency translation gains or losses due to spot rate fluctuations are reported as a component of accumulated other comprehensive loss. Derivative contracts that are not designated as hedging instruments are recorded at fair value with the gain or loss recognized in earnings during the period of change. We may enter into foreign currency forward or option contracts to reduce the effect of fluctuating currency exchange rates (principally the euro, British pound, and the Japanese yen). Foreign currency derivatives used for hedging are put in place using the same or like currencies and duration as the underlying exposures. Forward and option contracts are principally used to manage exposures arising from subsidiary trade and loan payables and receivables denominated in foreign currencies. These contracts are recorded at fair value with the gain or loss recognized in other–net, (income) expense. We may enter into foreign currency forward and option contracts and currency swaps as fair value hedges of firm commitments. Forward contracts generally have maturities not exceeding 12 months.

Revenue (Tables)

6 Months Ended

Jun. 30, 2019

Revenue from Contract with Customer [Abstract]

Schedule of disaggregation of revenue

The following table summarizes our revenue recognized in our consolidated condensed statements of operations:



	Three Months Ended June 30,				Six Months Ended June 30,
	2019		2018		2019		2018
Net product revenue	$	5,168.7	$	5,129.4	$	9,861.0	$	9,735.3
Collaboration and other revenue ⁽¹⁾	468.0		455.6		867.9		813.5
Revenue	$	5,636.7	$	5,585.0	$	10,728.9	$	10,548.8

The following table summarizes revenue by product:



	Three Months Ended June 30,
	2019						2018
	United States (U.S.) ⁽¹⁾		Outside U.S.		Total		U.S. ⁽¹⁾		Outside U.S.		Total
Revenue—to unaffiliated customers:
Endocrinology:
Trulicity^®	$	792.1	$	236.4	$	1,028.5	$	612.4	$	167.4	$	779.8
Humalog^{® (2)}	396.1		281.5		677.6		464.5		305.2		769.8
Forteo^®	172.8		188.0		360.8		225.1		209.4		434.5
Humulin^®	220.1		102.6		322.6		238.8		107.2		346.0
Basaglar^®	232.2		58.6		290.7		156.5		45.3		201.8
Jardiance ⁽³⁾	142.6		89.3		231.9		85.6		61.6		147.2
Trajenta ⁽⁴⁾	64.5		89.5		153.9		56.8		84.9		141.7
Other Endocrinology	81.6		59.3		141.2		61.5		72.8		134.1
Total Endocrinology	2,102.0		1,105.2		3,207.2		1,901.2		1,053.8		2,954.9

Oncology:
Alimta^®	341.7		236.1		577.8		281.3		274.6		555.9
Cyramza^®	89.8		152.0		241.8		75.4		143.3		218.8
Erbitux^®	136.9		22.4		159.3		140.0		26.4		166.4
Verzenio^®	105.2		28.7		133.9		57.7		—		57.7
Other Oncology	16.2		68.2		84.4		56.7		54.7		111.3
Total Oncology	689.8		507.4		1,197.2		611.1		499.0		1,110.1

Neuroscience:
Cymbalta^®	18.1		169.0		187.2		12.6		169.4		181.9
Zyprexa^®	9.3		95.1		104.3		11.8		116.2		128.0
Strattera^®	21.2		61.4		82.6		16.9		97.3		114.2
Emgality^®	33.8		0.5		34.3		—		—		—
Other Neuroscience	22.0		22.3		44.3		24.3		22.4		46.9
Total Neuroscience	104.4		348.3		452.7		65.6		405.3		471.0

Immunology:
Taltz^®	268.1		85.7		353.8		173.6		46.5		220.1
Olumiant^®	10.7		91.7		102.4		1.7		42.9		44.7
Total Immunology	278.8		177.3		456.1		175.3		89.4		264.7

Other:
Cialis^®	35.1		165.1		200.2		345.7		193.0		538.7
Other	42.4		80.8		123.3		143.4		102.2		245.6
Total Other	77.5		245.9		323.5		489.1		295.2		784.3
Revenue	$	3,252.5	$	2,384.2	$	5,636.7	$	3,242.3	$	2,342.7	$	5,585.0

Numbers may not add due to rounding.

⁽¹⁾U.S. revenue includes revenue in Puerto Rico.

⁽²⁾Humalog revenue includes Insulin Lispro.

⁽³⁾Jardiance revenue includes Glyxambi^®and Synjardy^®.

⁽⁴⁾Trajenta revenue includes Jentadueto^®.



	Six Months Ended June 30,
	2019						2018
	U.S. ⁽¹⁾		Outside U.S.		Total		U.S. ⁽¹⁾		Outside U.S.		Total
Revenue—to unaffiliated customers:
Endocrinology:
Trulicity	$	1,457.7	$	450.6	$	1,908.3	$	1,140.6	$	317.5	$	1,458.1
Humalog ⁽²⁾	844.8		563.7		1,408.4		968.7		592.8		1,561.5
Forteo	298.7		375.0		673.7		347.2		400.5		747.8
Humulin	421.3		199.0		620.3		460.4		211.5		671.9
Basaglar	430.3		111.8		542.1		283.2		84.6		367.8
Jardiance ⁽³⁾	267.8		167.7		435.5		180.6		117.6		298.2
Trajenta ⁽⁴⁾	111.8		174.0		285.9		110.9		171.9		282.8
Other Endocrinology	143.5		119.6		263.1		125.4		140.2		265.6
Total Endocrinology	3,975.9		2,161.4		6,137.3		3,617.0		2,036.6		5,653.7

Oncology:
Alimta	623.5		453.5		1,076.9		526.7		528.9		1,055.5
Cyramza	164.9		275.2		440.0		143.7		258.7		402.4
Erbitux	250.3		27.5		277.7		261.3		54.7		316.1
Verzenio	198.7		44.6		243.3		87.4		—		87.4
Other Oncology	46.3		125.5		172.1		102.3		103.0		205.3
Total Oncology	1,283.7		926.3		2,210.0		1,121.4		945.3		2,066.7

Neuroscience:
Cymbalta	28.4		322.9		351.3		24.8		326.7		351.5
Zyprexa	18.6		193.0		211.5		20.6		230.0		250.6
Strattera	22.7		126.1		148.8		63.9		181.0		244.9
Emgality	46.0		2.6		48.5		—		—		—
Other Neuroscience	39.8		45.7		85.8		48.5		48.2		96.7
Total Neuroscience	155.5		690.3		845.9		157.8		785.9		943.7

Immunology:
Taltz	449.0		157.4		606.3		284.7		81.8		366.5
Olumiant	17.1		167.4		184.5		1.7		75.2		76.9
Total Immunology	466.0		324.8		790.8		286.5		157.0		443.4

Other:
Cialis	178.4		330.0		508.4		659.1		375.0		1,034.1
Other	83.8		152.8		236.5		196.1		211.1		407.2
Total Other	262.2		482.9		744.9		855.2		586.1		1,441.3
Revenue	$	6,143.3	$	4,585.6	$	10,728.9	$	6,037.9	$	4,510.9	$	10,548.8

Numbers may not add due to rounding.

⁽¹⁾U.S. revenue includes revenue in Puerto Rico.

⁽²⁾Humalog revenue includes Insulin Lispro.

⁽³⁾Jardiance revenue includes Glyxambiand Synjardy.

⁽⁴⁾Trajenta revenue includes Jentadueto.

The following table summarizes revenue by geographical area:



	Three Months Ended June 30,				Six Months Ended June 30,
	2019		2018		2019		2018
Revenue—to unaffiliated customers ⁽¹⁾:
United States ⁽²⁾	$	3,252.5	$	3,242.3	$	6,143.3	$	6,037.9
Europe	928.2		941.0		1,828.5		1,834.8
Japan	653.2		640.4		1,196.9		1,177.2
Other foreign countries	802.8		761.2		1,560.2		1,498.8
Revenue	$	5,636.7	$	5,585.0	$	10,728.9	$	10,548.8

Numbers may not add due to rounding.

⁽¹⁾Revenue is attributed to the countries based on the location of the customer.

⁽²⁾U.S. revenue includes revenue in Puerto Rico.

Schedule of amounts recorded for contract liabilities

The following table summarizes contract liability balances:



	June 30, 2019		December 31, 2018
Contract liabilities	$	277.6	$	294.9

Acquisitions and Divestiture (Tables)

6 Months Ended

Jun. 30, 2019

Business Combinations [Abstract]

Schedule of the amounts recognized for assets acquired and liabilities assumed as of the acquisition date

The following table summarizes the preliminary amounts recognized for assets acquired and liabilities assumed as of the acquisition date:



Estimated Fair Value at February 15, 2019
Acquired in-process research and development	$	4,670.0
Definite-lived intangibles ⁽¹⁾	960.0
Deferred income taxes	(1,134.3		)
Other assets and liabilities - net	(31.4		)
Total identifiable net assets	4,464.3
Goodwill ⁽²⁾	2,453.4
Total consideration transferred - net of cash acquired	$	6,917.7

Schedule of asset acquisition

The following table summarizes our asset acquisitions during the six months ended June 30, 2019 and June 30, 2018.



Counterparty	Compound(s) or Therapy	Acquisition Month	Phase of Development ⁽¹⁾	Acquired IPR&D Expense
AC Immune SA	Tau aggregation inhibitor small molecules for the potential treatment of Alzheimer's disease and other neurodegenerative diseases	January 2019	Pre-clinical	$	96.9
ImmuNext, Inc.	Novel immunometabolism target	March 2019	Pre-clinical	40.0
Avidity Biosciences, Inc.	Potential new medicines in immunology and other select indications	April 2019	Pre-clinical	25.0

Sigilon Therapeutics	Encapsulated cell therapies for the potential treatment of type 1 diabetes	April 2018	Pre-clinical	66.9
AurKa Pharma, Inc.	AK-01, an Aurora kinase A inhibitor	June 2018	Phase I	81.8
ARMO Biosciences, Inc.	Cancer therapy - pegilodecakin	June 2018	Phase III	1,475.8

⁽¹⁾The phase of development presented is as of the date of the arrangement and represents the phase of development of the most advanced asset acquired, where applicable.

Collaborations and Other Arrangements (Tables)

6 Months Ended

Jun. 30, 2019

Organization, Consolidation and Presentation of Financial Statements [Abstract]

Schedule of significant milestones and revenue recognized

The following table summarizes our significant milestones achieved:



Year	Event	Classification	Amount
2018	Regulatory approval in the U.S.	Intangible asset	$	100.0
2018	Began Phase III testing for systemic lupus erythematosus (SLE)	R&D Expense	20.0
2017	Regulatory approval in Europe	Intangible asset	65.0
	Regulatory approval in Japan	Intangible asset	15.0
	Began Phase III testing for atopic dermatitis	R&D expense	30.0
2016	Regulatory submissions in the U.S. and Europe	R&D expense	55.0



	Three Months Ended June 30,				Six Months Ended June 30,
	2019		2018		2019		2018
Basaglar	$	290.7	$	201.8	$	542.1	$	367.8
Jardiance	231.9		147.2		435.5		298.2
Trajenta	153.9		141.7		285.9		282.8

The following table summarizes our net product revenue recognized with respect to Olumiant:



	Three Months Ended June 30,				Six Months Ended June 30,
	2019		2018		2019		2018
Olumiant	$	102.4	$	44.7	$	184.5	$	76.9

The table below summarizes significant milestones (deferred) capitalized for the compounds included in this collaboration:



Product Family	Milestones (Deferred) Capitalized ⁽¹⁾
Trajenta ⁽²⁾	$	446.4
Jardiance ⁽³⁾	289.0
Basaglar	(250.0		)

Discontinued Operations (Tables)

6 Months Ended

Jun. 30, 2019

Discontinued Operations and Disposal Groups [Abstract]

Summary of discontinued operations in consolidated condensed financial statements



	Three Months Ended June 30,					Six Months Ended June 30,
	2019		2018			2019		2018
Revenue	$	—	$	770.2		$	580.0	$	1,506.4
Net income (loss) from discontinued operations	—		(28.3		)	3,680.5		21.9

The following table presents the major classes of assets and liabilities from discontinued operations:



	December 31, 2018
Inventories	$	1,013.7
Other current assets	1,215.4
Current assets of discontinued operations	$	2,229.1

Goodwill	$	2,980.9
Other intangibles, net	2,453.0
Property and equipment, net	923.4
Other assets	126.8
Noncurrent assets of discontinued operations	$	6,484.1

Current liabilities of discontinued operations	$	692.8

Long-term debt	$	2,443.3
Other liabilities	299.0
Noncurrent liabilities of discontinued operations	$	2,742.3

Restructuring and Related Activities [Abstract]

Tabular disclosure of information related to a disposal group. Includes, but is not limited to, a discontinued operation, disposal classified as held-for-sale or disposed of by means other than sale or disposal of an individually significant component.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 360
-SubTopic 10
-Section 50
-Paragraph 3A
-URI http://asc.fasb.org/extlink&oid=109226691&loc=SL51724579-110230

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 3
-URI http://asc.fasb.org/extlink&oid=109222650&loc=d3e1474-107760

Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 5D
-URI http://asc.fasb.org/extlink&oid=109222650&loc=SL51721677-107760

Reference 4: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 45
-Paragraph 11
-URI http://asc.fasb.org/extlink&oid=109222160&loc=SL51721533-107759

Reference 5: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 3A
-URI http://asc.fasb.org/extlink&oid=109222650&loc=SL51721659-107760

Reference 6: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 4B
-URI http://asc.fasb.org/extlink&oid=109222650&loc=SL51721665-107760

Reference 7: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 360
-SubTopic 10
-Section 50
-Paragraph 3
-URI http://asc.fasb.org/extlink&oid=109226691&loc=d3e2941-110230

Reference 8: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 5C
-URI http://asc.fasb.org/extlink&oid=109222650&loc=SL51721675-107760

Reference 9: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 7
-URI http://asc.fasb.org/extlink&oid=109222650&loc=SL51721683-107760

Reference 10: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 1
-URI http://asc.fasb.org/extlink&oid=109222650&loc=d3e1361-107760

Reference 11: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 5A
-URI http://asc.fasb.org/extlink&oid=109222650&loc=SL51721671-107760

Reference 12: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 5B
-URI http://asc.fasb.org/extlink&oid=109222650&loc=SL51721673-107760

Reference 13: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 205
-SubTopic 20
-Section 50
-Paragraph 4A
-URI http://asc.fasb.org/extlink&oid=109222650&loc=SL51721663-107760

+ Details

Asset Impairment, Restructuring, and Other Special Charges (Tables)

6 Months Ended

Jun. 30, 2019

The components of the charges included in asset impairment, restructuring, and other special charges

The components of the charges included in asset impairment, restructuring, and other special charges in our consolidated condensed statements of operations are described below.



	Three Months Ended June 30,					Six Months Ended June 30,
	2019		2018			2019			2018
Severance	$	—	$	(24.6	)	$	(3.6	)	$	(17.3	)
Asset impairment and other special charges	—		(0.9		)	427.5			48.6
Total asset impairment, restructuring, and other special charges	$	—	$	(25.5	)	$	423.9		$	31.3

Financial Instruments (Tables)

6 Months Ended

Jun. 30, 2019

Fair Value Disclosures [Abstract]

Schedule of effects of risk-management instruments were recognized in other–net, (income) expense

The following effects of risk-management instruments were recognized in other–net, (income) expense:



	Three Months Ended June 30,						Six Months Ended June 30,
	2019			2018			2019			2018
Fair value hedges:
Effect from hedged fixed-rate debt	$	59.3		$	(19.7	)	$	98.5		$	(74.5	)
Effect from interest rate contracts	(59.3		)	19.7			(98.5		)	74.5
Cash flow hedges:
Effective portion of losses on interest rate contracts reclassified from accumulated other comprehensive loss	4.0			3.7			7.8			7.3
Net (gains) losses on foreign currency exchange contracts not designated as hedging instruments	(8.5		)	59.1			40.4			75.7
Total	$	(4.5	)	$	62.8		$	48.2		$	83.0

Schedule of effective portion of risk-management instruments that was recognized in other comprehensive income (loss)

The effective portion of risk-management instruments that was recognized in other comprehensive income (loss) is as follows:



	Three Months Ended June 30,					Six Months Ended June 30,
	2019			2018		2019			2018
Net investment hedges:
Foreign currency-denominated notes	$	(30.4	)	$	208.5	$	23.3		$	100.8
Cross-currency interest rate swaps	(4.3		)	69.1		34.0			37.6
Cash flow hedges:
Forward-starting interest rate swaps	—			—		(11.7		)	—
Cross-currency interest rate swaps	(7.4		)	—		(37.5		)	—

Summary certain fair value information



					Fair Value Measurements Using
	Carrying Amount		Cost ⁽¹⁾		Quoted Prices in Active Markets for Identical Assets (Level 1)		Significant Other Observable Inputs (Level 2)		Significant Unobservable Inputs (Level 3)		Fair Value
June 30, 2019
Cash equivalents	$	982.1	$	982.1	$	982.1	$	—	$	—	$	982.1

Short-term investments:
U.S. government and agency securities	$	3.9	$	3.9	$	3.9	$	—	$	—	$	3.9
Corporate debt securities	72.4		72.3		—		72.4		—		72.4
Other securities	1.4		1.4		—		1.4		—		1.4
Short-term investments	$	77.7

Noncurrent investments:
U.S. government and agency securities	$	82.3	$	81.6	$	82.3	$	—	$	—	$	82.3
Corporate debt securities	411.2		408.0		—		411.2		—		411.2
Mortgage-backed securities	95.1		94.4		—		95.1		—		95.1
Asset-backed securities	33.3		33.0		—		33.3		—		33.3
Other securities	82.1		40.0		—		—		82.1		82.1
Marketable equity securities	466.5		228.0		466.5		—		—		466.5
Equity investments without readily determinable fair values ⁽²⁾	398.6
Equity method investments ⁽²⁾	283.6
Noncurrent investments	$	1,852.7

December 31, 2018
Cash equivalents	$	5,727.1	$	5,727.1	$	5,727.1	$	—	$	—	$	5,727.1

Short-term investments:
U.S. government and agency securities	$	16.9	$	17.1	$	16.9	$	—	$	—	$	16.9
Corporate debt securities	62.2		62.6		—		62.2		—		62.2
Asset-backed securities	7.6		7.7		—		7.6		—		7.6
Other securities	1.5		1.5		—		1.5		—		1.5
Short-term investments	$	88.2

Noncurrent investments:
U.S. government and agency securities	$	149.1	$	153.6	$	149.1	$	—	$	—	$	149.1
Corporate debt securities	568.0		587.8		—		568.0		—		568.0
Mortgage-backed securities	111.4		114.5		—		111.4		—		111.4
Asset-backed securities	27.7		27.9		—		27.7		—		27.7
Other securities	87.8		29.7		—		—		87.8		87.8
Marketable equity securities	357.5		238.3		357.5		—		—		357.5
Equity investments without readily determinable fair values ⁽²⁾	414.7
Equity method investments ⁽²⁾	289.2
Noncurrent investments	$	2,005.4

⁽¹⁾For available-for-sale debt securities, amounts disclosed represent the securities' amortized cost.

⁽²⁾Fair value disclosures are not applicable for equity method investments and investments accounted for under the measurement alternative for equity investments.

Summary certain fair value information, liabilities



				Fair Value Measurements Using
	Carrying Amount			Quoted Prices in Active Markets for Identical Assets (Level 1)		Significant Other Observable Inputs (Level 2)			Significant Unobservable Inputs (Level 3)		Fair Value
Short-term commercial paper borrowings
June 30, 2019	$	(2,058.3	)	$	—	$	(2,049.8	)	$	—	$	(2,049.8	)
December 31, 2018	(498.9		)	—		(497.6		)	—		(497.6		)
Long-term debt, including current portion
June 30, 2019	$	(13,727.9	)	$	—	$	(14,833.0	)	$	—	$	(14,833.0	)
December 31, 2018	(9,799.7		)	—		(9,970.0		)	—		(9,970.0		)

Fair value, by balance sheet grouping



				Fair Value Measurements Using
	Carrying Amount			Quoted Prices in Active Markets for Identical Assets (Level 1)		Significant Other Observable Inputs (Level 2)			Significant Unobservable Inputs (Level 3)		Fair Value
June 30, 2019
Risk-management instruments:
Interest rate contracts designated as fair value hedges:
Sundry	$	82.4		$	—	$	82.4		$	—	$	82.4
Cross-currency interest rate contracts designated as net investment hedges:
Other receivables	16.9			—		16.9			—		16.9
Sundry	26.4			—		26.4			—		26.4
Other current liabilities	(3.6		)	—		(3.6		)	—		(3.6		)
Other noncurrent liabilities	(2.1		)	—		(2.1		)	—		(2.1		)
Cross-currency interest rate contracts designated as cash flow hedges:
Other noncurrent liabilities	(19.0		)	—		(19.0		)	—		(19.0		)
Foreign exchange contracts not designated as hedging instruments:
Other receivables	17.6			—		17.6			—		17.6
Other current liabilities	(11.7		)	—		(11.7		)	—		(11.7		)

December 31, 2018
Risk-management instruments:
Interest rate contracts designated as fair value hedges:
Sundry	4.5			—		4.5			—		4.5
Other current liabilities	(22.3		)	—		(22.3		)	—		(22.3		)
Other noncurrent liabilities	(19.0		)	—		(19.0		)	—		(19.0		)
Cross-currency interest rate contracts designated as net investment hedges:
Other receivables	69.2			—		69.2			—		69.2
Sundry	8.2			—		8.2			—		8.2
Other current liabilities	(9.2		)	—		(9.2		)	—		(9.2		)
Cross-currency interest rate contracts not designated as hedging instruments
Other noncurrent liabilities	(25.8		)	—		(25.8		)	—		(25.8		)
Foreign exchange contracts not designated as hedging instruments:
Other receivables	11.3			—		11.3			—		11.3
Other current liabilities	(16.3		)	—		(16.3		)	—		(16.3		)

Summary the contractual maturities of our investments in debt securities measured at fair value

The table below summarizes the contractual maturities of our investments in debt securities measured at fair value as of June 30, 2019:



	Maturities by Period
	Total		Less Than 1 Year		1-5 Years		6-10 Years		More Than 10 Years
Fair value of debt securities	$	698.3	$	76.3	$	447.1	$	61.4	$	113.5

Summary of the amount of unrealized gains and losses (pretax) recognized in our statement of operations for equity securities



	June 30, 2019		December 31, 2018
Unrealized gross gains	$	9.3	$	0.8
Unrealized gross losses	4.1		29.0
Fair value of securities in an unrealized gain position	441.9		84.3
Fair value of securities in an unrealized loss position	255.8		858.6

Activity related to our investment portfolio, substantially all of which related to equity and available-for-sale securities, was as follows:



	Three Months Ended June 30,				Six Months Ended June 30,
	2019		2018		2019		2018
Proceeds from sales	$	362.9	$	4,953.8	$	456.6	$	5,546.4
Realized gross gains on sales	13.0		5.6		15.5		7.7
Realized gross losses on sales	6.4		47.4		6.8		49.0

Leases (Tables)

6 Months Ended

Jun. 30, 2019

Leases [Abstract]

Schedule of impact of leases to consolidated condensed financial statements

Supplemental balance sheet information related to operating leases as of June 30, 2019 was as follows:




Weighted-average remaining lease term	8 years
Weighted-average discount rate	3.7	%

Supplemental cash flow information related to operating leases for the six months ended June 30, 2019 was as follows:




Operating cash flows from operating leases	$	72.7
Right-of-use assets obtained in exchange for new operating lease liabilities	46.2

Schedule of maturities of operating lease liabilities

he annual minimum lease payments of our operating lease liabilities as of June 30, 2019 were as follows:




Year 1	$	135.0
Year 2	113.9
Year 3	80.2
Year 4	67.6
Year 5	56.3
After Year 5	276.6
Total lease payments	729.6
Less imputed interest	(108.0		)
Total	$	621.6

Retirement Benefits (Tables)

6 Months Ended

Jun. 30, 2019

Defined Benefit Plans and Other Postretirement Benefit Plans Disclosures [Abstract]

Schedule of net pension and retiree health benefit (income) cost

Net pension and retiree health benefit (income) cost included the following components:



	Defined Benefit Pension Plans						Defined Benefit Pension Plans
	Three Months Ended June 30,						Six Months Ended June 30,
	2019			2018			2019			2018
Components of net periodic benefit cost:
Service cost	$	63.5		$	74.9		$	125.4		$	152.5
Interest cost	122.6			111.4			243.3			223.3
Expected return on plan assets	(210.1		)	(210.0		)	(421.2		)	(420.9		)
Amortization of prior service cost	1.5			1.3			3.0			2.4
Recognized actuarial loss	73.1			91.1			142.7			181.1
Net periodic benefit cost	$	50.6		$	68.7		$	93.2		$	138.4



	Retiree Health Benefit Plans						Retiree Health Benefit Plans
	Three Months Ended June 30,						Six Months Ended June 30,
	2019			2018			2019			2018
Components of net periodic benefit income:
Service cost	$	9.4		$	10.9		$	18.2		$	21.6
Interest cost	14.4			13.5			29.0			27.4
Expected return on plan assets	(36.0		)	(43.9		)	(71.9		)	(87.8		)
Amortization of prior service benefit	(15.7		)	(20.4		)	(31.5		)	(40.9		)
Recognized actuarial loss	0.4			2.2			0.9			4.6
Net periodic benefit income	$	(27.5	)	$	(37.7	)	$	(55.3	)	$	(75.1	)

Other Comprehensive Income (Loss) (Tables)

6 Months Ended

Jun. 30, 2019

Statement of Comprehensive Income [Abstract]

Schedule of components of other comprehensive income (loss)

The tax effects on the net activity related to each component of other comprehensive income (loss) were as follows:



	Three Months Ended June 30,						Six Months Ended June 30,
Tax benefit (expense)	2019			2018			2019			2018
Foreign currency translation gains/losses	$	7.3		$	(58.3	)	$	(12.0	)	$	(18.2	)
Unrealized net gains/losses on securities	(2.1		)	(8.9		)	(6.9		)	1.3
Defined benefit pension and retiree health benefit plans	(13.4		)	(23.6		)	(24.8		)	(37.9		)
Effective portion of cash flow hedges	0.7			(0.7		)	8.7			(1.5		)
Benefit/(provision) for income taxes allocated to other comprehensive income (loss) items	$	(7.5	)	$	(91.5	)	$	(35.0	)	$	(56.3	)

The following tables summarize the activity related to each component of other comprehensive income (loss) during the three months ended June 30, 2019 and 2018:



	Continuing Operations
(Amounts presented net of taxes)	Foreign Currency Translation Gains (Losses)			Unrealized Net Gains (Losses) on Securities			Defined Benefit Pension and Retiree Health Benefit Plans			Effective Portion of Cash Flow Hedges			Discontinued Operations		Accumulated Other Comprehensive Loss
Balance at April 1, 2019	$	(1,601.4	)	$	(3.6	)	$	(3,813.7	)	$	(268.8	)	$	—	$	(5,687.5	)

Other comprehensive income (loss) before reclassifications	31.4			8.4			3.4			(6.1		)	—		37.1
Net amount reclassified from accumulated other comprehensive loss	—			(0.3		)	47.0			3.2			—		49.9
Net other comprehensive income (loss)	31.4			8.1			50.4			(2.9		)	—		87.0

Balance at June 30, 2019	$	(1,570.0	)	$	4.5		$	(3,763.3	)	$	(271.7	)	$	—	$	(5,600.5	)



	Continuing Operations
(Amounts presented net of taxes)	Foreign Currency Translation Gains (Losses)			Unrealized Net Gains (Losses) on Securities			Defined Benefit Pension and Retiree Health Benefit Plans			Effective Portion of Cash Flow Hedges			Discontinued Operations			Accumulated Other Comprehensive Loss
Balance at April 1, 2018	$	(900.2	)	$	(51.0	)	$	(4,274.4	)	$	(231.5	)	$	19.6		$	(5,437.5	)

Other comprehensive income (loss) before reclassifications	(661.3		)	65.9			55.8			0.1			(160.9		)	(700.4		)
Net amount reclassified from accumulated other comprehensive loss	—			(33.0		)	58.6			2.9			0.7			29.2
Net other comprehensive income (loss)	(661.3		)	32.9			114.4			3.0			(160.2		)	(671.2		)

Balance at June 30, 2018	$	(1,561.5	)	$	(18.1	)	$	(4,160.0	)	$	(228.5	)	$	(140.6	)	$	(6,108.7	)

The following tables summarize the activity related to each component of other comprehensive income (loss) during the six months ended June 30, 2019 and 2018:



	Continuing Operations
(Amounts presented net of taxes)	Foreign Currency Translation Gains (Losses)			Unrealized Net Gains (Losses) on Securities			Defined Benefit Pension and Retiree Health Benefit Plans			Effective Portion of Cash Flow Hedges			Discontinued Operations			Accumulated Other Comprehensive Loss
Balance at January 1, 2019 ⁽¹⁾	$	(1,569.7	)	$	(22.1	)	$	(3,852.7	)	$	(238.9	)	$	(56.8	)	$	(5,740.2	)

Other comprehensive income (loss) before reclassifications	(0.3		)	25.2			(2.3		)	(39.0		)	(27.2		)	(43.6		)
Net amount reclassified from accumulated other comprehensive loss	—			1.4			91.7			6.2			84.0			183.3
Net other comprehensive income (loss)	(0.3		)	26.6			89.4			(32.8		)	56.8			139.7

Balance at June 30, 2019	$	(1,570.0	)	$	4.5		$	(3,763.3	)	$	(271.7	)	$	—		$	(5,600.5	)



	Continuing Operations
(Amounts presented net of taxes)	Foreign Currency Translation Gains (Losses)			Unrealized Net Gains (Losses) on Securities			Defined Benefit Pension and Retiree Health Benefit Plans			Effective Portion of Cash Flow Hedges			Discontinued Operations			Accumulated Other Comprehensive Loss
Balance at January 1, 2018 ⁽²⁾	$	(1,191.7	)	$	113.5		$	(4,311.3	)	$	(234.3	)	$	(71.1	)	$	(5,694.9	)

Reclassification due to adoption of new accounting standard ⁽³⁾	—			(128.9		)	—			—			—			(128.9		)
Other comprehensive income (loss) before reclassifications	(369.8		)	29.9			35.0			—			(70.9		)	(375.8		)
Net amount reclassified from accumulated other comprehensive loss	—			(32.6		)	116.3			5.8			1.4			90.9
Net other comprehensive income (loss)	(369.8		)	(2.7		)	151.3			5.8			(69.5		)	(284.9		)

Balance at June 30, 2018	$	(1,561.5	)	$	(18.1	)	$	(4,160.0	)	$	(228.5	)	$	(140.6	)	$	(6,108.7	)

Schedule of reclassifications out of accumulated other comprehensive loss

Reclassifications out of accumulated other comprehensive loss were as follows:



Details about Accumulated Other Comprehensive Loss Components	Three Months Ended June 30,						Six Months Ended June 30,						Affected Line Item in the Consolidated Condensed Statements of Operations
	Three Months Ended June 30,						Six Months Ended June 30,
	2019			2018			2019			2018
Amortization of retirement benefit items:
Prior service benefits, net	$	(14.2	)	$	(19.1	)	$	(28.5	)	$	(38.5	)	Other–net, (income) expense
Actuarial losses, net	73.5			93.3			143.6			185.7			Other–net, (income) expense
Total before tax	59.3			74.2			115.1			147.2
Tax benefit	(12.3		)	(15.6		)	(23.4		)	(30.9		)	Income taxes
Net of tax	47.0			58.6			91.7			116.3

Other, net of tax	2.9			(30.1		)	7.6			(26.8		)	Other–net, (income) expense
Reclassifications from continuing operations (net of tax)	49.9			28.5			99.3			89.5
Reclassifications from discontinued operations (net of tax)	—			0.7			84.0			1.4			Net income from discontinued operations
Total reclassifications for the period (net of tax)	$	49.9		$	29.2		$	183.3		$	90.9

Other–Net, (Income) Expense (Tables)

6 Months Ended

Jun. 30, 2019

Nonoperating Income (Expense) [Abstract]

Schedule of other–net, (income) expense

Other–net, (income) expense consisted of the following:



	Three Months Ended June 30,						Six Months Ended June 30,
	2019			2018			2019			2018
Interest expense	$	110.9		$	63.3		$	197.4		$	124.5
Interest income	(19.4		)	(41.2		)	(50.0		)	(86.7		)
Retirement benefit plans	(49.8		)	(54.8		)	(105.7		)	(110.8		)
Other income	(9.3		)	(13.9		)	(95.3		)	(43.1		)
Other–net, (income) expense	$	32.4		$	(46.6	)	$	(53.6	)	$	(116.1	)

Basis of Presentation and Implementation of New Financial Accounting Standards (Details) - USD ($) $ in Millions	Jun. 30, 2019	Mar. 11, 2019	Jan. 01, 2019	Dec. 31, 2018
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Operating lease assets	$ 545.5		$ 530.0	$ 0.0
Reclassification of deferred rent net of prepaid rent, as a component of the operating lease asset	(277.6)			$ (294.9)
Operating lease liabilities	$ 621.6		595.0
Accounting Standards Update 2016-02
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Reclassification of deferred rent net of prepaid rent, as a component of the operating lease asset			$ 65.0
Discontinued Operations, Disposed of by Sale \| Elanco Animal Health Incorporated
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Noncontrolling interest, ownership percentage by parent		80.20%

Revenue (Summary of Revenue Recognized) (Details) - USD ($) $ in Millions	3 Months Ended		6 Months Ended
	Jun. 30, 2019	Jun. 30, 2018	Jun. 30, 2019	Jun. 30, 2018
Disaggregation of Revenue [Line Items]
Revenue	$ 5,636.7	$ 5,585.0	$ 10,728.9	$ 10,548.8
Net product revenue
Disaggregation of Revenue [Line Items]
Revenue	5,168.7	5,129.4	9,861.0	9,735.3
Collaboration and other revenue
Disaggregation of Revenue [Line Items]
Revenue	468.0	455.6	867.9	813.5
Royalty
Disaggregation of Revenue [Line Items]
Revenue	$ 59.6	$ 133.6	$ 95.1	$ 183.7

Revenue (Disaggregation of Revenue by Product) (Details) - USD ($) $ in Millions	3 Months Ended		6 Months Ended
	Jun. 30, 2019	Jun. 30, 2018	Jun. 30, 2019	Jun. 30, 2018
Disaggregation of Revenue [Line Items]
Revenue	$ 5,636.7	$ 5,585.0	$ 10,728.9	$ 10,548.8
U.S.
Disaggregation of Revenue [Line Items]
Revenue	3,252.5	3,242.3	6,143.3	6,037.9
Outside U.S.
Disaggregation of Revenue [Line Items]
Revenue	2,384.2	2,342.7	4,585.6	4,510.9
Endocrinology
Disaggregation of Revenue [Line Items]
Revenue	3,207.2	2,954.9	6,137.3	5,653.7
Endocrinology \| U.S.
Disaggregation of Revenue [Line Items]
Revenue	2,102.0	1,901.2	3,975.9	3,617.0
Endocrinology \| Outside U.S.
Disaggregation of Revenue [Line Items]
Revenue	1,105.2	1,053.8	2,161.4	2,036.6
Trulicity®
Disaggregation of Revenue [Line Items]
Revenue	1,028.5	779.8	1,908.3	1,458.1
Trulicity® \| U.S.
Disaggregation of Revenue [Line Items]
Revenue	792.1	612.4	1,457.7	1,140.6
Trulicity® \| Outside U.S.
Disaggregation of Revenue [Line Items]
Revenue	236.4	167.4	450.6	317.5
Humalog®
Disaggregation of Revenue [Line Items]
Revenue	677.6	769.8	1,408.4	1,561.5
Humalog® \| U.S.
Disaggregation of Revenue [Line Items]
Revenue	396.1	464.5	844.8	968.7
Humalog® \| Outside U.S.
Disaggregation of Revenue [Line Items]
Revenue	281.5	305.2	563.7	592.8
Forteo®
Disaggregation of Revenue [Line Items]
Revenue	360.8	434.5	673.7	747.8
Forteo® \| U.S.
Disaggregation of Revenue [Line Items]
Revenue	172.8	225.1	298.7	347.2
Forteo® \| Outside U.S.
Disaggregation of Revenue [Line Items]
Revenue	188.0	209.4	375.0	400.5
Humulin®
Disaggregation of Revenue [Line Items]
Revenue	322.6	346.0	620.3	671.9
Humulin® \| U.S.
Disaggregation of Revenue [Line Items]
Revenue	220.1	238.8	421.3	460.4
Humulin® \| Outside U.S.
Disaggregation of Revenue [Line Items]
Revenue	102.6	107.2	199.0	211.5
Basaglar®
Disaggregation of Revenue [Line Items]
Revenue	290.7	201.8	542.1	367.8
Basaglar® \| U.S.
Disaggregation of Revenue [Line Items]
Revenue	232.2	156.5	430.3	283.2
Basaglar® \| Outside U.S.
Disaggregation of Revenue [Line Items]
Revenue	58.6	45.3	111.8	84.6
Jardiance
Disaggregation of Revenue [Line Items]
Revenue	231.9	147.2	435.5	298.2
Jardiance \| U.S.
Disaggregation of Revenue [Line Items]
Revenue	142.6	85.6	267.8	180.6
Jardiance \| Outside U.S.
Disaggregation of Revenue [Line Items]
Revenue	89.3	61.6	167.7	117.6
Trajenta
Disaggregation of Revenue [Line Items]
Revenue	153.9	141.7	285.9	282.8
Trajenta \| U.S.
Disaggregation of Revenue [Line Items]
Revenue	64.5	56.8	111.8	110.9
Trajenta \| Outside U.S.
Disaggregation of Revenue [Line Items]
Revenue	89.5	84.9	174.0	171.9
Other Endocrinology
Disaggregation of Revenue [Line Items]
Revenue	141.2	134.1	263.1	265.6
Other Endocrinology \| U.S.
Disaggregation of Revenue [Line Items]
Revenue	81.6	61.5	143.5	125.4
Other Endocrinology \| Outside U.S.
Disaggregation of Revenue [Line Items]
Revenue	59.3	72.8	119.6	140.2
Oncology
Disaggregation of Revenue [Line Items]
Revenue	1,197.2	1,110.1	2,210.0	2,066.7
Oncology \| U.S.
Disaggregation of Revenue [Line Items]
Revenue	689.8	611.1	1,283.7	1,121.4
Oncology \| Outside U.S.
Disaggregation of Revenue [Line Items]
Revenue	507.4	499.0	926.3	945.3
Alimta®
Disaggregation of Revenue [Line Items]
Revenue	577.8	555.9	1,076.9	1,055.5
Alimta® \| U.S.
Disaggregation of Revenue [Line Items]
Revenue	341.7	281.3	623.5	526.7
Alimta® \| Outside U.S.
Disaggregation of Revenue [Line Items]
Revenue	236.1	274.6	453.5	528.9
Cyramza®
Disaggregation of Revenue [Line Items]
Revenue	241.8	218.8	440.0	402.4
Cyramza® \| U.S.
Disaggregation of Revenue [Line Items]
Revenue	89.8	75.4	164.9	143.7
Cyramza® \| Outside U.S.
Disaggregation of Revenue [Line Items]
Revenue	152.0	143.3	275.2	258.7
Erbitux®
Disaggregation of Revenue [Line Items]
Revenue	159.3	166.4	277.7	316.1
Erbitux® \| U.S.
Disaggregation of Revenue [Line Items]
Revenue	136.9	140.0	250.3	261.3
Erbitux® \| Outside U.S.
Disaggregation of Revenue [Line Items]
Revenue	22.4	26.4	27.5	54.7
Verzenio®
Disaggregation of Revenue [Line Items]
Revenue	133.9	57.7	243.3	87.4
Verzenio® \| U.S.
Disaggregation of Revenue [Line Items]
Revenue	105.2	57.7	198.7	87.4
Verzenio® \| Outside U.S.
Disaggregation of Revenue [Line Items]
Revenue	28.7	0.0	44.6	0.0
Other Oncology
Disaggregation of Revenue [Line Items]
Revenue	84.4	111.3	172.1	205.3
Other Oncology \| U.S.
Disaggregation of Revenue [Line Items]
Revenue	16.2	56.7	46.3	102.3
Other Oncology \| Outside U.S.
Disaggregation of Revenue [Line Items]
Revenue	68.2	54.7	125.5	103.0
Neuroscience
Disaggregation of Revenue [Line Items]
Revenue	452.7	471.0	845.9	943.7
Neuroscience \| U.S.
Disaggregation of Revenue [Line Items]
Revenue	104.4	65.6	155.5	157.8
Neuroscience \| Outside U.S.
Disaggregation of Revenue [Line Items]
Revenue	348.3	405.3	690.3	785.9
Cymbalta®
Disaggregation of Revenue [Line Items]
Revenue	187.2	181.9	351.3	351.5
Cymbalta® \| U.S.
Disaggregation of Revenue [Line Items]
Revenue	18.1	12.6	28.4	24.8
Cymbalta® \| Outside U.S.
Disaggregation of Revenue [Line Items]
Revenue	169.0	169.4	322.9	326.7
Zyprexa®
Disaggregation of Revenue [Line Items]
Revenue	104.3	128.0	211.5	250.6
Zyprexa® \| U.S.
Disaggregation of Revenue [Line Items]
Revenue	9.3	11.8	18.6	20.6
Zyprexa® \| Outside U.S.
Disaggregation of Revenue [Line Items]
Revenue	95.1	116.2	193.0	230.0
Strattera®
Disaggregation of Revenue [Line Items]
Revenue	82.6	114.2	148.8	244.9
Strattera® \| U.S.
Disaggregation of Revenue [Line Items]
Revenue	21.2	16.9	22.7	63.9
Strattera® \| Outside U.S.
Disaggregation of Revenue [Line Items]
Revenue	61.4	97.3	126.1	181.0
Emgality®
Disaggregation of Revenue [Line Items]
Revenue	34.3	0.0	48.5	0.0
Emgality® \| U.S.
Disaggregation of Revenue [Line Items]
Revenue	33.8	0.0	46.0	0.0
Emgality® \| Outside U.S.
Disaggregation of Revenue [Line Items]
Revenue	0.5	0.0	2.6	0.0
Other Neuroscience
Disaggregation of Revenue [Line Items]
Revenue	44.3	46.9	85.8	96.7
Other Neuroscience \| U.S.
Disaggregation of Revenue [Line Items]
Revenue	22.0	24.3	39.8	48.5
Other Neuroscience \| Outside U.S.
Disaggregation of Revenue [Line Items]
Revenue	22.3	22.4	45.7	48.2
Immunology
Disaggregation of Revenue [Line Items]
Revenue	456.1	264.7	790.8	443.4
Immunology \| U.S.
Disaggregation of Revenue [Line Items]
Revenue	278.8	175.3	466.0	286.5
Immunology \| Outside U.S.
Disaggregation of Revenue [Line Items]
Revenue	177.3	89.4	324.8	157.0
Taltz®
Disaggregation of Revenue [Line Items]
Revenue	353.8	220.1	606.3	366.5
Taltz® \| U.S.
Disaggregation of Revenue [Line Items]
Revenue	268.1	173.6	449.0	284.7
Taltz® \| Outside U.S.
Disaggregation of Revenue [Line Items]
Revenue	85.7	46.5	157.4	81.8
Olumiant®
Disaggregation of Revenue [Line Items]
Revenue	102.4	44.7	184.5	76.9
Olumiant® \| U.S.
Disaggregation of Revenue [Line Items]
Revenue	10.7	1.7	17.1	1.7
Olumiant® \| Outside U.S.
Disaggregation of Revenue [Line Items]
Revenue	91.7	42.9	167.4	75.2
Other
Disaggregation of Revenue [Line Items]
Revenue	323.5	784.3	744.9	1,441.3
Other \| U.S.
Disaggregation of Revenue [Line Items]
Revenue	77.5	489.1	262.2	855.2
Other \| Outside U.S.
Disaggregation of Revenue [Line Items]
Revenue	245.9	295.2	482.9	586.1
Cialis®
Disaggregation of Revenue [Line Items]
Revenue	200.2	538.7	508.4	1,034.1
Cialis® \| U.S.
Disaggregation of Revenue [Line Items]
Revenue	35.1	345.7	178.4	659.1
Cialis® \| Outside U.S.
Disaggregation of Revenue [Line Items]
Revenue	165.1	193.0	330.0	375.0
Other
Disaggregation of Revenue [Line Items]
Revenue	123.3	245.6	236.5	407.2
Other \| U.S.
Disaggregation of Revenue [Line Items]
Revenue	42.4	143.4	83.8	196.1
Other \| Outside U.S.
Disaggregation of Revenue [Line Items]
Revenue	$ 80.8	$ 102.2	$ 152.8	$ 211.1

Revenue (Disaggregation of Revenue by Geographical Area) (Details) - USD ($) $ in Millions	3 Months Ended		6 Months Ended
	Jun. 30, 2019	Jun. 30, 2018	Jun. 30, 2019	Jun. 30, 2018
Disaggregation of Revenue [Line Items]
Revenue	$ 5,636.7	$ 5,585.0	$ 10,728.9	$ 10,548.8
U.S.
Disaggregation of Revenue [Line Items]
Revenue	3,252.5	3,242.3	6,143.3	6,037.9
Europe
Disaggregation of Revenue [Line Items]
Revenue	928.2	941.0	1,828.5	1,834.8
Japan
Disaggregation of Revenue [Line Items]
Revenue	653.2	640.4	1,196.9	1,177.2
Other foreign countries
Disaggregation of Revenue [Line Items]
Revenue	$ 802.8	$ 761.2	$ 1,560.2	$ 1,498.8

Revenue (Narrative) (Details)	3 Months Ended		6 Months Ended
Revenue (Narrative) (Details)	Jun. 30, 2019	Jun. 30, 2018	Jun. 30, 2019	Jun. 30, 2018
U.S. \| Sales returns, rebates, and discounts
Change in Accounting Estimate [Line Items]
Revenue, information used to determine revenue recognized, change in accounting estimate, percent	4.00%	1.00%	3.00%	2.00%

Revenue (Contract Liabilities) (Details) - USD ($) $ in Millions	Jun. 30, 2019	Dec. 31, 2018
Revenue from Contract with Customer [Abstract]
Contract liabilities	$ 277.6	$ 294.9

Acquisitions and Divestiture (Narrative) (Details) $ in Millions	1 Months Ended			3 Months Ended		6 Months Ended
	Jul. 31, 2019 USD ($)	Apr. 30, 2019 USD ($) medicine	Feb. 28, 2019 USD ($)	Jun. 30, 2019 USD ($)	Jun. 30, 2018 USD ($)	Jun. 30, 2019 USD ($)	Jun. 30, 2018 USD ($)
Business Acquisition [Line Items]
Acquired in-process research and development				$ 25.0	$ 1,624.5	$ 161.9	$ 1,624.5
Loxo Oncology, Inc.
Business Acquisition [Line Items]
Purchase price			$ 6,920.0
Centrexion Therapeutics Corporation \| CNTX-0290 \| Subsequent Event
Business Acquisition [Line Items]
Acquired in-process research and development	$ 47.5
License and research collaboration agreement, upfront fee	$ 47.5
Legacy Antibiotic Medicines and Manufacturing Facility in Suzhou, China \| Disposal Group, Held-for-sale, Not Discontinued Operations \| Eddingpharm
Business Acquisition [Line Items]
Number of medicines, rights to, agreed to be sold \| medicine		2
Disposal group, not discontinued operation, deposit to be received		$ 75.0
Disposal group, not discontinued operation, payment to be received		$ 300.0

Acquisitions and Divestiture (Assets Acquired and Liabilities Assumed) (Details) - USD ($) $ in Millions	Feb. 15, 2019	Jun. 30, 2019	Dec. 31, 2018
Business Acquisition [Line Items]
Goodwill		$ 3,820.1	$ 1,366.6
Loxo Oncology, Inc.
Business Acquisition [Line Items]
Acquired in-process research and development	$ 4,670.0
Definite-lived intangibles	960.0
Deferred income taxes	(1,134.3)
Other assets and liabilities - net	(31.4)
Total identifiable net assets	4,464.3
Goodwill	2,453.4
Total consideration transferred - net of cash acquired	$ 6,917.7
Contract-Based Intangible Assets \| Loxo Oncology, Inc.
Business Acquisition [Line Items]
Useful life	12 years

Acquisitions and Divestiture (Asset Acquisitions) (Details) - USD ($) $ in Millions	1 Months Ended					3 Months Ended		6 Months Ended
	Apr. 30, 2019	Mar. 31, 2019	Jan. 31, 2019	Jun. 30, 2018	Apr. 30, 2018	Jun. 30, 2019	Jun. 30, 2018	Jun. 30, 2019	Jun. 30, 2018
Business Acquisition [Line Items]
Acquired in-process research and development						$ 25.0	$ 1,624.5	$ 161.9	$ 1,624.5
AC Immune SA
Business Acquisition [Line Items]
Acquired in-process research and development			$ 96.9
ImmuNext, Inc.
Business Acquisition [Line Items]
Acquired in-process research and development		$ 40.0
Avidity Biosciences, Inc.
Business Acquisition [Line Items]
Acquired in-process research and development	$ 25.0
Sigilon Therapeutics
Business Acquisition [Line Items]
Acquired in-process research and development					$ 66.9
AurKa Pharma, Inc.
Business Acquisition [Line Items]
Acquired in-process research and development				$ 81.8
ARMO Biosciences, Inc.
Business Acquisition [Line Items]
Acquired in-process research and development				$ 1,475.8

Collaborations and Other Arrangements (Details) - USD ($) $ in Millions	3 Months Ended		6 Months Ended		12 Months Ended
	Jun. 30, 2019	Jun. 30, 2018	Jun. 30, 2019	Jun. 30, 2018	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2016
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue	$ 5,636.7	$ 5,585.0	$ 10,728.9	$ 10,548.8
R&D expense	1,402.2	1,271.0	2,632.7	2,378.5
U.S.
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue	3,252.5	3,242.3	6,143.3	6,037.9
Europe
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue	928.2	941.0	1,828.5	1,834.8
Japan
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue	653.2	640.4	1,196.9	1,177.2
Basaglar
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue	290.7	201.8	542.1	367.8
Basaglar \| U.S.
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue	232.2	156.5	430.3	283.2
Jardiance
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue	231.9	147.2	435.5	298.2
Jardiance \| U.S.
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue	142.6	85.6	267.8	180.6
Trajenta
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue	153.9	141.7	285.9	282.8
Trajenta \| U.S.
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue	64.5	56.8	111.8	110.9
Olumiant®
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue	102.4	44.7	184.5	76.9
Olumiant® \| U.S.
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Revenue	$ 10.7	$ 1.7	17.1	$ 1.7
Milestone Payments, Development and Regulatory, Capitalized, Cumulative \| Basaglar
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestones (deferred) capitalized			(250.0)
Milestone Payments, Development and Regulatory, Capitalized, Cumulative \| Jardiance
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestones (deferred) capitalized			289.0
Milestone Payments, Development and Regulatory, Capitalized, Cumulative \| Trajenta
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestones (deferred) capitalized			$ 446.4
Royalty Agreement Terms \| Olumiant®
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaborative arrangement, rights and obligations, percentage			20.00%
Milestone Payments, Development and Regulatory, Capitalized (Deferred) \| Olumiant® \| U.S.
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestones (deferred) capitalized					$ 100.0
Milestone Payments, Development and Regulatory, Capitalized (Deferred) \| Olumiant® \| Europe
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestones (deferred) capitalized						$ 65.0
Milestone Payments, Development and Regulatory, Capitalized (Deferred) \| Olumiant® \| Japan
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestones (deferred) capitalized						15.0
Milestone Payments, Development and Regulatory, Expensed \| Olumiant®
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
R&D expense					$ 20.0	$ 30.0	$ 55.0
Milestone Payments, Development and Regulatory \| Olumiant®
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestones (deferred) capitalized			$ 130.0
Milestone Payments, Development and Regulatory \| Tanezumab
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestones (deferred) capitalized			350.0
Milestone Payments, Sales-based \| Olumiant®
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestones (deferred) capitalized			150.0
Milestone Payments, Sales-based \| Tanezumab
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Milestones (deferred) capitalized			$ 1,230.0
Research and Development Exp \| Olumiant®
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaborative arrangement, rights and obligations, percentage			30.00%

Discontinued Operations (Narrative) (Details) - USD ($) $ in Millions		6 Months Ended
	Mar. 11, 2019	Jun. 30, 2019	Jun. 30, 2018
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Gain on disposition of business		$ 3,680.5	$ 0.0
Elanco Animal Health Incorporated \| Discontinued Operations, Disposed of by Sale
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Noncontrolling interest, ownership percentage by parent	80.20%
Gain on disposition of business		$ 3,700.0
Transitional services agreement, term	24 months

Discontinued Operations (Discontinued Operations in Financial Statements) (Details) - USD ($) $ in Millions	3 Months Ended		6 Months Ended
	Jun. 30, 2019	Jun. 30, 2018	Jun. 30, 2019	Jun. 30, 2018
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Revenue	$ 5,636.7	$ 5,585.0	$ 10,728.9	$ 10,548.8
Net income (loss) from discontinued operations	0.0	(28.3)	3,680.5	21.9
Elanco Animal Health Incorporated \| Discontinued Operations, Disposed of by Sale
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Revenue	$ 0.0	$ 770.2	$ 580.0	$ 1,506.4

AOCI Including Portion Attributable to Noncontrolling Interest, Net of Tax [Roll Forward]

Amount after tax of income (loss) from a discontinued operation including the portion attributable to the noncontrolling interest. Includes, but is not limited to, the income (loss) from operations during the phase-out period, gain (loss) on disposal, gain (loss) for reversal of write-down (write-down) to fair value, less cost to sell, and adjustments to a prior period gain (loss) on disposal.

+ References + Details

Discontinued Operations (Major Classes of Assets and Liabilities) (Details) - USD ($) $ in Millions	Jun. 30, 2019	Dec. 31, 2018
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Current assets of discontinued operations	$ 0.0	$ 2,229.1
Noncurrent assets of discontinued operations	0.0	6,484.1
Current liabilities of discontinued operations	0.0	692.8
Noncurrent liabilities of discontinued operations	$ 0.0	2,742.3
Elanco Animal Health Incorporated \| Discontinued Operations, Disposed of by Sale
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Inventories		1,013.7
Other current assets		1,215.4
Current assets of discontinued operations		2,229.1
Goodwill		2,980.9
Other intangibles, net		2,453.0
Property and equipment, net		923.4
Other assets		126.8
Noncurrent assets of discontinued operations		6,484.1
Current liabilities of discontinued operations		692.8
Long-term debt		2,443.3
Other liabilities		299.0
Noncurrent liabilities of discontinued operations		$ 2,742.3

Asset Impairment, Restructuring, and Other Special Charges (Details) - USD ($) $ in Millions	3 Months Ended		6 Months Ended
	Jun. 30, 2019	Jun. 30, 2018	Jun. 30, 2019	Jun. 30, 2018
Business Acquisition [Line Items]
Severance	$ 0.0	$ (24.6)	$ (3.6)	$ (17.3)
Asset impairment and other special charges	0.0	(0.9)	427.5	48.6
Total asset impairment, restructuring, and other special charges	$ 0.0	$ (25.5)	423.9	$ 31.3
Loxo Oncology, Inc.
Business Acquisition [Line Items]
Asset impairment and other special charges			$ 400.7

Financial Instruments (Narrative) (Details) € in Millions, ¥ in Millions, £ in Millions, $ in Millions	1 Months Ended	3 Months Ended		6 Months Ended
	Feb. 28, 2019 USD ($)	Jun. 30, 2019 USD ($)	Jun. 30, 2018 USD ($)	Jun. 30, 2019 USD ($)	Jun. 30, 2018 USD ($)	Jun. 30, 2019 EUR (€)	Jun. 30, 2019 GBP (£)	Jun. 30, 2019 JPY (¥)	Dec. 31, 2018 USD ($)
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Maximum remaining maturity of foreign currency derivatives				30 days
Derivatives used in net investment hedge, net of tax		$ 2,360.0		$ 2,360.0					$ 2,380.0
Percentage of long-term fixed-rate notes to floating rates through the use of interest rate swaps converted		15.00%		15.00%		15.00%	15.00%	15.00%
Interest rate cash flow hedge losses to be reclassified during next 12 months		$ 16.2		$ 16.2
Equity securities, net unrealized gains and (losses)		6.3	$ 20.8	$ 156.0	$ 38.6
OTTI recognized			$ 0.0		$ 0.0
Available-for-sale, percentage of nonperforming assets				40.00%
Amount of receivable derecognized		696.4		$ 696.4					696.2
Buy U.S. Dollars Sell Euros
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Derivative liability, notional amount		605.3		605.3
Derivative asset, notional amount \| €						€ 535.9
Buy Euros Sell U.S. Dollars
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Derivative liability, notional amount \| €						€ 1,140.0
Derivative asset, notional amount		1,280.0		1,280.0
Buy U.S. Dollars Sell Japanese Yen
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Derivative liability, notional amount		279.4		279.4
Derivative asset, notional amount \| ¥								¥ 30,220
Buy British Pounds and Sell U.S. Dollars
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Derivative liability, notional amount \| £							£ 237.6
Derivative asset, notional amount		299.7		299.7
Swap U.S. Dollars to Euro
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Derivative, notional amount		1,930.0		1,930.0
Swap Swiss Francs to U.S. Dollars
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Derivative, notional amount		1,000.0		1,000.0
Swap U.S. Dollars to British Pounds
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Derivative, notional amount		143.0		143.0
Foreign Currency Denominated Debt
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Long-term debt, including current portion		$ 3,380.0		$ 3,380.0					$ 3,400.0
Senior Notes
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Proceeds from issuance of notes	$ 4,450.0
Senior Notes Due March 2029 \| Senior Notes
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Debt instrument, face amount	$ 1,150.0
Stated interest rate	3.38%
Senior Notes Due March 2039 \| Senior Notes
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Debt instrument, face amount	$ 850.0
Stated interest rate	3.88%
Senior Notes Due March 2049 \| Senior Notes
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Debt instrument, face amount	$ 1,500.0
Stated interest rate	3.95%
Senior Notes Due March 2059 \| Senior Notes
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Debt instrument, face amount	$ 1,000.0
Stated interest rate	4.15%

Financial Instruments (Effect of Risk-Management Instruments) (Details) - USD ($) $ in Millions	3 Months Ended		6 Months Ended
	Jun. 30, 2019	Jun. 30, 2018	Jun. 30, 2019	Jun. 30, 2018
Cash flow hedges:
Total	$ (4.5)	$ 62.8	$ 48.2	$ 83.0
Foreign currency-denominated notes \| Net investment hedges
Cash flow hedges:
Effective portion of risk-management instruments that was recognized in other comprehensive income (loss)	(30.4)	208.5	23.3	100.8
Cross-currency interest rate swaps \| Net investment hedges
Cash flow hedges:
Effective portion of risk-management instruments that was recognized in other comprehensive income (loss)	(4.3)	69.1	34.0	37.6
Cross-currency interest rate swaps \| Cash flow hedges
Cash flow hedges:
Effective portion of risk-management instruments that was recognized in other comprehensive income (loss)	(7.4)	0.0	(37.5)	0.0
Forward-starting interest rate swaps \| Cash flow hedges
Cash flow hedges:
Effective portion of risk-management instruments that was recognized in other comprehensive income (loss)	0.0	0.0	(11.7)	0.0
Designated as Hedging Instrument \| Foreign currency-denominated notes
Fair value hedges:
Effect from hedged fixed-rate debt	59.3	(19.7)	98.5	(74.5)
Designated as Hedging Instrument \| Interest rate contracts
Fair value hedges:
Effect from interest rate contracts	(59.3)	19.7	(98.5)	74.5
Cash flow hedges:
Effective portion of losses on interest rate contracts reclassified from accumulated other comprehensive loss	4.0	3.7	7.8	7.3
Not Designated as Hedging Instrument \| Foreign currency exchange contracts
Cash flow hedges:
Net (gains) losses on foreign currency exchange contracts not designated as hedging instruments	$ (8.5)	$ 59.1	$ 40.4	$ 75.7

Financial Instruments (Contractual Maturities) (Details) $ in Millions	Jun. 30, 2019 USD ($)
Debt Securities Contractual Maturities
Total	$ 698.3
Less Than 1 Year	76.3
1-5 Years	447.1
6-10 Years	61.4
More Than 10 Years	$ 113.5

Financial Instruments (Unrealized Gains and Losses) (Details) - USD ($) $ in Millions	Jun. 30, 2019	Dec. 31, 2018
Fair Value Disclosures [Abstract]
Unrealized gross gains	$ 9.3	$ 0.8
Unrealized gross losses	4.1	29.0
Fair value of securities in an unrealized gain position	441.9	84.3
Fair value of securities in an unrealized loss position	$ 255.8	$ 858.6

Financial Instruments (Realized Gains and Losses) (Details) - USD ($) $ in Millions	3 Months Ended		6 Months Ended
	Jun. 30, 2019	Jun. 30, 2018	Jun. 30, 2019	Jun. 30, 2018
Fair Value Disclosures [Abstract]
Proceeds from sales	$ 362.9	$ 4,953.8	$ 456.6	$ 5,546.4
Realized gross gains on sales	13.0	5.6	15.5	7.7
Realized gross losses on sales	$ 6.4	$ 47.4	$ 6.8	$ 49.0

Leases (Narrative) (Details) - USD ($) $ in Millions	3 Months Ended	6 Months Ended
Leases (Narrative) (Details) - USD ($) $ in Millions	Jun. 30, 2019	Jun. 30, 2019
Leases [Abstract]
Lessee, lease, remaining lease term (up to)		13 years
Operating lease cost	$ 34.0	$ 66.1

Leases (Impact of Leases to Consolidated Condensed Financial Statements) (Details) $ in Millions	6 Months Ended
	Jun. 30, 2019 USD ($)
Leases [Abstract]
Weighted-average remaining lease term	8 years
Weighted-average discount rate	3.70%
Operating cash flows from operating leases	$ 72.7
Right-of-use assets obtained in exchange for new operating lease liabilities	$ 46.2

Leases (Maturities of Operating Lease Liabilities) (Details) - USD ($) $ in Millions	Jun. 30, 2019	Jan. 01, 2019
Leases [Abstract]
Year 1	$ 135.0
Year 2	113.9
Year 3	80.2
Year 4	67.6
Year 5	56.3
After Year 5	276.6
Total lease payments	729.6
Less imputed interest	(108.0)
Total	$ 621.6	$ 595.0

Income Taxes (Details) - USD ($) $ in Millions	3 Months Ended		6 Months Ended
Income Taxes (Details) - USD ($) $ in Millions	Jun. 30, 2019	Jun. 30, 2018	Jun. 30, 2019	Jun. 30, 2018
Operating Loss Carryforwards [Line Items]
Effective income tax rate, percentage	9.50%		14.10%	33.50%
Income tax expense	$ 138.7	$ 273.3	$ 308.7	$ 471.8
Income before income taxes	1,465.9	41.7	$ 2,197.0	$ 1,407.4
Tax Year 2013
Operating Loss Carryforwards [Line Items]
Income tax year under examination			2013
Tax Year 2015
Operating Loss Carryforwards [Line Items]
Income tax year under examination			2015
Decrease in unrecognized tax benefits is reasonably possible	100.0		$ 100.0
Tax Years 2013 to 2015
Operating Loss Carryforwards [Line Items]
Decrease in unrecognized tax benefits is reasonably possible	200.0		$ 200.0
Income tax settlement payment	$ 125.0
ARMO and AurKa
Operating Loss Carryforwards [Line Items]
Nondeductible expense, research and development, amount		$ 1,560.0

Retirement Benefits (Narrative) (Details) $ in Millions	6 Months Ended
Retirement Benefits (Narrative) (Details) $ in Millions	Jun. 30, 2019 USD ($)
Defined Benefit Plans and Other Postretirement Benefit Plans Disclosures [Abstract]
Pension contributions	$ 20
Estimated future employer contributions in current fiscal year	30
Payment for additional discretionary funding	$ 0

Retirement Benefits (Components of Net Periodic Benefit Cost) (Details) - USD ($) $ in Millions	3 Months Ended		6 Months Ended
	Jun. 30, 2019	Jun. 30, 2018	Jun. 30, 2019	Jun. 30, 2018
Defined Benefit Pension Plans
Defined Benefit Plan Disclosure [Line Items]
Service cost	$ 63.5	$ 74.9	$ 125.4	$ 152.5
Interest cost	122.6	111.4	243.3	223.3
Expected return on plan assets	(210.1)	(210.0)	(421.2)	(420.9)
Amortization of prior service cost	1.5	1.3	3.0	2.4
Recognized actuarial loss	73.1	91.1	142.7	181.1
Net periodic benefit cost	50.6	68.7	93.2	138.4
Retiree Health Benefit Plans
Defined Benefit Plan Disclosure [Line Items]
Service cost	9.4	10.9	18.2	21.6
Interest cost	14.4	13.5	29.0	27.4
Expected return on plan assets	(36.0)	(43.9)	(71.9)	(87.8)
Amortization of prior service cost	(15.7)	(20.4)	(31.5)	(40.9)
Recognized actuarial loss	0.4	2.2	0.9	4.6
Net periodic benefit cost	$ (27.5)	$ (37.7)	$ (55.3)	$ (75.1)

Contingencies (Details) R$ in Millions, $ in Millions		1 Months Ended		6 Months Ended
Contingencies (Details) R$ in Millions, $ in Millions	Jun. 30, 2019 USD ($) company request patent demand application	Jul. 31, 2019 BRL (R$)	Jul. 31, 2018 BRL (R$)	Jun. 30, 2019 USD ($) case company request patent lawsuit plaintiff demand defendant application
Dr Reddy's Lab
Loss Contingencies [Line Items]
Claims settled and dismissed \| case				2
Japanese Administrative Proceedings
Loss Contingencies [Line Items]
Number of demands \| demand	3			3
Number of patents \| patent	2			2
Adocia S.A
Loss Contingencies [Line Items]
Number of patents \| patent	2			2
Amount of claim \| $	$ 1,390			$ 1,390
Gain contingency, unrecorded amount \| $	$ 188			$ 188
Insulin Pricing Litigation and Proceedings
Loss Contingencies [Line Items]
Number of requests for information from Committee on Energy and Commerce \| request	2			2
U.S. \| Alimta®
Loss Contingencies [Line Items]
Number of new application \| application	10			10
Number of defendants \| defendant				2
Number of companies \| company	5			5
Brazil \| Employee Litigation
Loss Contingencies [Line Items]
Damages awarded, value	$ 130		R$ 500
Number of lawsuits \| lawsuit				30
Plaintiff Appealing Decision of Court \| Brazil \| Employee Litigation
Loss Contingencies [Line Items]
Number of similar lawsuits \| lawsuit				2
Number of individuals				410
Plaintiff Appealing Decision of Court \| Brazil \| Employee Litigation, Similar Lawsuit One
Loss Contingencies [Line Items]
Number of individuals				305
Plaintiff Appealing Decision of Court \| Brazil \| Employee Litigation, Similar Lawsuit Two
Loss Contingencies [Line Items]
Number of individuals				105
Subsequent Event \| Brazil \| Employee Litigation
Loss Contingencies [Line Items]
Damages awarded, value \| R$		R$ 500

Other Comprehensive Income (Loss) (AOCI) (Details) - USD ($)
$ in Millions

3 Months Ended

6 Months Ended

Jun. 30, 2019

Jun. 30, 2018

Jun. 30, 2019

Jun. 30, 2018

Jan. 01, 2018

Reclassification due to adoption of new accounting standard

$ 10,909.1

$ (128.9)

Other comprehensive income (loss) before reclassifications

$ 37.1

$ (700.4)

(43.6)

$ (375.8)

Net amount reclassified from accumulated other comprehensive loss

49.9

29.2

183.3

90.9

87.0

^[1]

(671.2)

^[1]

139.7

(284.9)

Accumulated Other Comprehensive Loss

2,857.3

AOCI Including Portion Attributable to Noncontrolling Interest, Net of Tax [Roll Forward]

(5,687.5)

(5,437.5)

(5,740.2)

(5,694.9)

AOCI Attributable to Parent

(5,600.5)

(6,108.7)

(5,600.5)

(6,108.7)

AOCI Including Portion Attributable to Noncontrolling Interest, Net of Tax [Roll Forward]

Reclassification due to adoption of new accounting standard

(5,687.5)

(5,437.5)

(5,729.2)

(5,718.6)

(105.2)

AOCI Attributable to Noncontrolling Interest

(5,600.5)

(6,108.7)

(5,600.5)

(6,108.7)

AOCI Including Portion Attributable to Noncontrolling Interest, Net of Tax [Roll Forward]

Reclassification due to adoption of new accounting standard

11.0

23.7

(23.7)

Continuing Operations

AOCI Including Portion Attributable to Noncontrolling Interest, Net of Tax [Roll Forward]

Continuing Operations | Foreign Currency Translation Gains (Losses)

87.0

(511.0)

82.9

(215.4)

AOCI Including Portion Attributable to Noncontrolling Interest, Net of Tax [Roll Forward]

Reclassification due to adoption of new accounting standard

(1,601.4)

(900.2)

(1,569.7)

(1,191.7)

0.0

Other comprehensive income (loss) before reclassifications

31.4

(661.3)

(0.3)

(369.8)

Net amount reclassified from accumulated other comprehensive loss

0.0

31.4

(661.3)

(0.3)

(369.8)

Continuing Operations | Unrealized Net Gains (Losses) on Securities

(1,570.0)

(1,561.5)

(1,570.0)

(1,561.5)

AOCI Including Portion Attributable to Noncontrolling Interest, Net of Tax [Roll Forward]

Reclassification due to adoption of new accounting standard

(3.6)

(51.0)

(22.1)

113.5

(128.9)

Other comprehensive income (loss) before reclassifications

8.4

65.9

25.2

29.9

Net amount reclassified from accumulated other comprehensive loss

(0.3)

(33.0)

1.4

(32.6)

8.1

32.9

26.6

(2.7)

Continuing Operations | Defined Benefit Pension and Retiree Health Benefit Plans

4.5

(18.1)

4.5

(18.1)

AOCI Including Portion Attributable to Noncontrolling Interest, Net of Tax [Roll Forward]

Reclassification due to adoption of new accounting standard

(3,813.7)

(4,274.4)

(3,852.7)

(4,311.3)

0.0

Other comprehensive income (loss) before reclassifications

3.4

55.8

(2.3)

35.0

Net amount reclassified from accumulated other comprehensive loss

47.0

58.6

91.7

116.3

50.4

114.4

89.4

151.3

Continuing Operations | Effective Portion of Cash Flow Hedges

(3,763.3)

(4,160.0)

(3,763.3)

(4,160.0)

AOCI Including Portion Attributable to Noncontrolling Interest, Net of Tax [Roll Forward]

Reclassification due to adoption of new accounting standard

(268.8)

(231.5)

(238.9)

(234.3)

0.0

Other comprehensive income (loss) before reclassifications

(6.1)

0.1

(39.0)

0.0

Net amount reclassified from accumulated other comprehensive loss

3.2

2.9

6.2

5.8

(2.9)

3.0

(32.8)

5.8

AOCI Including Portion Attributable to Noncontrolling Interest, Net of Tax [Roll Forward]

(271.7)

(228.5)

(271.7)

(228.5)

Discontinued Operations

Discontinued Operations | Accumulated Other Comprehensive Loss

^[1]

0.0

(160.2)

56.8

(69.5)

AOCI Including Portion Attributable to Noncontrolling Interest, Net of Tax [Roll Forward]

Reclassification due to adoption of new accounting standard

0.0

19.6

(56.8)

(71.1)

$ 0.0

Other comprehensive income (loss) before reclassifications

0.0

(160.9)

(27.2)

(70.9)

Net amount reclassified from accumulated other comprehensive loss

0.0

0.7

84.0

1.4

0.0

(160.2)

56.8

(69.5)

Discontinued Operations | AOCI Attributable to Parent

0.0

$ (140.6)

0.0

$ (140.6)

AOCI Including Portion Attributable to Noncontrolling Interest, Net of Tax [Roll Forward]

Discontinued Operations | AOCI Attributable to Noncontrolling Interest

45.8

AOCI Including Portion Attributable to Noncontrolling Interest, Net of Tax [Roll Forward]