Boehringer Ingelheim and Eli Lilly and Company submit new drug application to FDA for empagliflozin, an investigational type 2 diabetes treatment
Empagliflozin is a member of the SGLT2 inhibitor class of drugs being
investigated for the reduction of blood glucose levels in adults with T2D. The emerging SGLT2 inhibitor class removes excess glucose through the urine by blocking glucose re-absorption in the kidney.
"We are excited to have submitted an application for a potential new treatment option that may help patients better manage their type 2 diabetes mellitus," said
Empagliflozin is being investigated in adults with T2D in a Phase III clinical trial program that plans to enroll more than 14,500 patients.[1] In total, this program comprises 12 multinational clinical trials, including a large cardiovascular outcome trial. Boehringer Ingelheim and Lilly plan to present detailed data disclosures for many of these studies at scientific medical meetings and in publications in 2013 and 2014.
About Diabetes
Approximately 25.8 million Americans[2] and an estimated 371 million people worldwide[3] have type 1 or type 2 diabetes. T2D is the most common type, accounting for an estimated 90 percent of all diabetes cases.[2] Diabetes is a chronic disease that occurs when the body either does not properly produce, or use, the hormone insulin.[4] Diabetes was estimated to cost the U.S.
Boehringer Ingelheim and
In
About Boehringer Ingelheim
The Boehringer Ingelheim group is one of the world's 20 leading pharmaceutical companies. Headquartered in Ingelheim,
As a central element of its culture, Boehringer Ingelheim pledges to act socially responsibly. Involvement in social projects, caring for employees and their families, and providing equal opportunities for all employees form the foundation of the global operations. Mutual cooperation and respect, as well as environmental protection and sustainability are intrinsic factors in all of Boehringer Ingelheim's endeavors.
In 2011, Boehringer Ingelheim achieved net sales of about
For more information, please visit http://us.boehringer-ingelheim.com and follow us on Twitter at http://twitter.com/boehringerus.
About
Lilly, a leading innovation-driven corporation, is developing a growing portfolio of pharmaceutical products by applying the latest research from its own worldwide laboratories and from collaborations with eminent scientific organizations. Headquartered in
About Lilly Diabetes
Lilly has been a global leader in diabetes care since 1923, when we introduced the world's first commercial insulin. Today we work to meet the diverse needs of people with diabetes through research and collaboration, a broad and growing product portfolio and our continued commitment to providing real solutions — from medicines to support programs and more — to make lives better.
For more information, visit www.lillydiabetes.com.
This press release contains forward-looking statements about empagliflozin* for the treatment of type 2 diabetes. It reflects Lilly's current beliefs; however, as with any such undertaking, there are substantial risks and uncertainties in the process of drug development and commercialization. There is no guarantee that future study results and patient experience will be consistent with study findings to date or that empagliflozin* will prove to be commercially successful. For further discussion of these and other risks and uncertainties, please see Lilly's latest Forms 10-Q and 10-K filed with the
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CONTACT:
Catherine London
Associate Director, Communications and Public Relations
Email: usnews@boehringer-ingelheim.com
Phone: (203) 798-4638
Communications Manager
Lilly Diabetes
Email: hullta@lilly.com
Phone: (317) 651-9116
[1] Data on file,
[2]
[3]
[4]
http://www.idf.org/diabetesatlas/5e/what-is-diabetes. Accessed on:
[5]
*Empagliflozin is an investigational compound. Its safety and efficacy have not yet been fully established.
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