Survey Finds Half of Heart Stent Patients Don't Take Their Oral Antiplatelet Medication As Prescribed
To address this critical issue, the
"For people who have recently received a heart stent for ACS, changing, skipping or discontinuing OAP therapy increases the risk of serious heart problems or even death," said
To help ACS patients prevent recurrent heart events after an angioplasty procedure,
Annually, about 610,000 people with ACS, which includes heart attack and a type of chest pain called unstable angina (UA), undergo an angioplasty procedure to open a blocked coronary artery.[5][6][7] Clinical research shows that up to 16 percent of these patients stop taking their prescribed OAP therapy in the first 30 days,[1][8] which leaves them more vulnerable to another heart event and increases by 10-fold their risk of death at one year.[1]
"Patients may stop taking their OAP medication for a variety of reasons, such as mistakenly believing their heart condition is 'fixed' or not understanding why or how long they need to take the medication," said
To launch the "After the Stent: Follow Your Action PlanTM" campaign, PCNA and
Additionally, the groups have developed an OAP nonadherence risk Assessment for health care professionals to use with their patients. The Assessment includes the 8-question Morisky Medication Adherence Screener, widely used in other disease categories to assess medication adherence,[9][10][11][12] six questions specific to ACS patients who have undergone an angioplasty procedure, and a Conversation Guide to help health care professionals tailor conversations with individual patients based on the risk factors identified in the Assessment questionnaires.
Survey Reveals Education and Support Gap, Particularly for Younger Patients4
The survey also found that of the 296 respondents who visited a health care professional within the 12 months following their angioplasty procedure, 20 percent said they had questions about their prescribed OAP medication that were not addressed by their health care team. Most likely to have questions were those under age 65 (209 participants). Additionally, those under age 65 were less aware than those 65 years or older that not taking their OAP medication as prescribed could lead to future cardiac events (74 percent vs 88 percent of total respondents respectively)*. Moreover, only 54 percent of the total respondents overall said they remember being asked during a follow-up visit with their physician if they filled their OAP medication prescription.
"Coping with a heart event is an overwhelming experience for patients and their families, which makes it especially important that health care professionals take the time to explain what occurred and what needs to happen after the angioplasty procedure to help prevent another heart event," said
About Acute Coronary Syndrome (ACS)
ACS, which includes heart attack and a type of chest pain called unstable angina (UA), was responsible for the hospitalization of more than one million people in
Each year, approximately 610,000 people undergo PCI, which typically includes the implantation of a stent that restores blood flow to blocked arteries in the heart.[5][6][7] The number of UA or NSTEMI ACS patients worldwide who are managed without acute coronary interventions, such as PCI, has ranged from 32 percent to almost 60 percent over the last few years.[13][14]
ACS may result in heart attack, stroke and death, costing Americans more than
About the Survey
The survey was conducted online by Harris Poll on behalf of
About PCNA
About
About Mended Hearts
Mended Hearts is the largest heart patient support network in the world. 20,000 members operate through 300 chapters across the U.S. Recognized for its role in facilitating a positive patient-care experience, Mended Hearts partners with 460 hospitals and rehabilitation clinics and offers services to heart patients through visiting programs, support group meetings and educational forums. The Mended Hearts is dedicated to inspiring hope in heart disease patients and their families.
About Daiichi Sankyo
About
Lilly is a global healthcare leader that unites caring with discovery to make life better for people around the world. We were founded more than a century ago by a man committed to creating high-quality medicines that meet real needs, and today we remain true to that mission in all our work. Across the globe, Lilly employees work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to communities through philanthropy and volunteerism. To learn more about Lilly, please visit us at www.lilly.com, @LillyHealth on Twitter and newsroom.lilly.com/social-channels.
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*Finding is directional in nature as 65+ sample is < 100.
[1] Spertus JA, Kettelkamp R, Vance C, et al. Prevalence, predictors, and outcomes of premature discontinuation of thienopyridine therapy after drug-eluting stent placement: results from the PREMIER registry. Circulation. 2006;113:2803-2809.
[2] Rothberg MB, Sivalingam SK, Ashraf J, et al. Patients' and Cardiologists' Perceptions of the Benefits of Percutaneous Coronary Intervention for Stable Coronary Disease. Ann Intern Med. 2010;153:307-313.
[3] Levine GN, Bates ER, Blankenship JC, et al. 2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention: Executive Summary: A Report of the
[4]Study conducted online by Harris Poll on
behalf of
[5] Go AS, Mozaffarian D, Roger VL, et al. for the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics - 2014 update. Circulation. Published online
[6] Gibson CM, Pride YB, Frederick PD, et al. Trends in Reperfusion Strategies, Door-to-Needle and Door-to-Balloon Times, and In-Hospital Mortality Among Patients with ST-Segment Elevation Myocardial Infarction
Enrolled in the
[7] Roe MT, Chen AY, Cannon CP, et al. Temporal Changes in the Use of Drug-Eluting Stents for Patients with Non-ST-Segment-Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention from 2006 to 2008. Circulation: Cardiovascular Quality Outcomes. 2009;2:414-420.
[8] Quadros A, Welter D, Camozzatto F. Identifying Patients at Risk for Premature Discontinuation of Thienopyridine After Coronary Stent Implantation.
[9] Morisky DE, Ang A, Krousel-Wood M,
[10] Trindade AJ, Ehrlich A, Kornbluth A, Ullman T. Are Your Patients Taking Their Medicine? Validation of a New Adherence Scale in Patients with Inflammatory Bowel Disease and Comparison with Physician Perception of Adherence. Inflamm Bowel Dis. 2011;17:599-604.
[11] Reynolds K, Viswanathan HN, O'Malley CD, et al.
[12] Krousel-Wood MA, Islam T, Webber LS, Re RS, Morisky DE, Muntner P. New Medication Adherence Scale Versus Pharmacy Fill Rates in Seniors with Hypertension. Am J Manag Care. 2009;15(1):59-66.
[13] Fox KAA, Steg PG, Eagle KA, et al. Decline in rates of death and heart failure in acute coronary syndromes,
1999-2006.
[14] Chan MY, Mahaffey KW, Sun LJ, et al. Prevalence, predictors, and impact of conservative medical management for patients with non-ST-segment elevation acute coronary syndromes who have angiographically documented significant coronary disease. J Am Coll Cardiol. 2008;1:369-378.
[15] Kolansky DM. Acute coronary syndromes: Morbidity, mortality and pharmacoeconomic burden. Am J Manag Care. 2009;15:S36-S41.
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